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1

Camara, NLY, A. Barry, O. Koulibaly, HZ Maomy, LT Soumaoro, B. Traoré und A. Touré. „Epidémiologie des cancers du tube digestif au service de chirurgie générale de l’hôpital national Ignace Deen“. Journal Africain des Cas Cliniques et Revues 9, Nr. 1 (13.01.2025): 1–7. https://doi.org/10.70065/2591.jaccrafri.001l011301.

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Introduction : Les cancers digestifs sont des tumeurs malignes qui se développent au niveau du tube digestif et ses annexes. Le but de notre étude était de déterminer le profil sociodémographique, clinique, thérapeutique des cancers digestifs dans le service de Chirurgie Générale de l’hôpital National Ignace Deen. Méthodologie : IL s’agit d’une étude observationnelle rétrospective monocentrique d’une durée de 10 ans allant du 1er janvier 2013 au 31 décembre 2022 portant sur l’ensemble des malades admis et pris en charge dans le service de chirurgie générale pour un cancer du tube digestif. Résultats : Les cancers digestifs représentaient ainsi 3,87% de l’ensemble des activités du service. L’âge moyen de nos patients était de 52,4 ans avec un sex-ratio de 1,77. La symptomatologie clinique est dominée par la douleur abdominale (38,34%), l'amaigrissement (32,70%). L'adénocarcinome était le type histologique le plus fréquent (64,7%).45,5% des patientes se présentent dans un stade métastatique au moment de diagnostic. Le traitement est basé sur la chirurgie Conclusion : Les cancers digestifs étaient relativement fréquents dans notre contexte, dominés par les cancers colo-rectaux (30,7%). Les circonstances de découverte était dominé par la douleur abdominale accompagné d’une altération de l’état général. Sur le plan histologique, il s’agissait le plus souvent d’un adénocarcinome chez 172 patients (64,7%). La chirurgie a été le seul moyen utilisé, 168 patients (63,1%) ont été opérés dont 69 patients opérés en urgence et 99 en chirurgie réglée. Mots-clés : Cancers digestifs, épidémiologie, CHU Ignace Deen.
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2

Bouvier, A. M., C. Lepage und J. Faivre. „Épidémiologie des cancers du tube digestif“. EMC - Gastro-entérologie 4, Nr. 2 (Januar 2009): 1–8. http://dx.doi.org/10.1016/s1155-1968(09)50903-0.

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3

Benhamiche-Bouvier, Anne-Marie, François Clinard, Vincent Dancourt und Jean Faivre. „Épidémiologie des cancers du tube digestif“. EMC - Gastro-entérologie 18, Nr. 3 (2001): 1–7. https://doi.org/10.1016/s1155-1968(01)00042-6.

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4

Cottet, V., C. Bonithon-Kopp und J. Faivre. „Prévention primaire des cancers du tube digestif“. EMC - Gastro-entérologie 1, Nr. 1 (Januar 2006): 1–9. http://dx.doi.org/10.1016/s1155-1968(06)74157-8.

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5

Cottet, V., C. Bonithon-Kopp und J. Faivre. „Prévention primaire des cancers du tube digestif“. EMC - Chirurgie 1, Nr. 1 (Februar 2004): 32–46. http://dx.doi.org/10.1016/j.emcchi.2003.10.002.

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6

Cottet, V., C. Bonithon-Kopp und J. Faivre. „Prévention primaire des cancers du tube digestif“. EMC - Gastro-entérologie 21, Nr. 1 (2004): 1–10. https://doi.org/10.1016/s1155-1968(04)27457-0.

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7

Bentefouet, TL, MD Fall, A. Sow, MM Diop und I. Thiam. „C36: Profil épidémiologique et anatomopathologique des polypes du tube digestif à Thiès (Sénégal) : A propos de 56 cas“. African Journal of Oncology 2, Nr. 1 Supplement (01.03.2022): S16. http://dx.doi.org/10.54266/ajo.2.1s.c36.wf4yqvyw4k.

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INTRODUCTION : Le polype correspond à des lésions en relief dans la lumière du tube digestif. Certains polypes classés comme bénins peuvent évoluer vers des lésions dysplasiques, puis vers un cancer. L’objectif de ce travail était d’étudier les aspects épidémiologiques et anatomopathologiques des polypes du tube digestif à Thiès et d’évaluer la fréquence et le degré de dysplasie dans les différentes lésions observées. MATERIELS ET METHODES : Il s’agit d’une étude rétrospective sur une période de cinq ans (2016 à 2020). Les données ont été collectés à partir des dossiers des patients au niveau du laboratoire d’Anatomie Pathologique de la région de Thiès. Pour chaque patient, nous avons établi une fiche d’exploitation comportant l’âge, le sexe, les circonstances de découverte, le siège du polype, le nombre de polype, l’aspect macroscopique, et le type histologique. Les données ont été saisies et analysées par le logiciel Excel© 2010 et SPSS© 20. RESULTATS : Nous avons colligé au total 56 cas de polypes du tube digestif. Le sex-ratio était d’un. L’âge moyen était de 38 ± 24 ans (trois à 84 ans). Les épigastralgies et les rectorragies, constituaient les principales circonstances de découverte. Les polypes siégeaient préférentiellement au niveau de l’estomac et du colon. Les autres localisations étaient rares dans l’ensemble du tube digestif à des proportions variables. Il s’agissait le plus souvent de polypes uniques avec dans la majorité des cas, une taille supérieure ou égale à 10 mm (48% des cas). Les types histologiques étaient variés et les lésions dysplasiques étaient retrouvées dans six cas (10,7%). CONCLUSION : Le dépistage précoce des polypes dysplasiques permet de prévenir la survenue de certains cancers digestifs gastriques et colorectaux.
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8

Barret, M., B. Terris und S. Chaussade. „Recommandations concernant les cancers superficiels du tube digestif. Partie 1 : règles générales de la prise en charge des cancers superficiels du tube digestif“. Acta Endoscopica 47, Nr. 4 (25.04.2017): 164–67. http://dx.doi.org/10.1007/s10190-017-0595-4.

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9

Terris, Benoit, Bertrand Brieau und Stanislas Chaussade. „Recommandations pour les cancers superficiels du tube digestif : cancer du côlon (CCR superficiels)“. Acta Endoscopica 47, Nr. 4 (03.06.2017): 168–73. http://dx.doi.org/10.1007/s10190-017-0596-z.

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10

Lecomte, T., B. Godart und G. Rahmi. „Recommandations : cancers superficiels du tube digestif. Prise en charge endoscopique des cancers superficiels de l’estomac“. Acta Endoscopica 47, Nr. 4 (20.06.2017): 180–86. http://dx.doi.org/10.1007/s10190-017-0599-9.

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11

Ionescu, Vlad-Alexandru, Gina Gheorghe, Ruxandra Oprita, Madalina Stan-Ilie, Raluca-Ioana Dascalu, Ondin Zaharia, Viorel Jinga, Camelia Cristina Diaconu und Gabriel Constantinescu. „The Outcomes of Nutritional Support Techniques in Patients with Gastrointestinal Cancers“. Gastroenterology Insights 13, Nr. 3 (05.08.2022): 245–57. http://dx.doi.org/10.3390/gastroent13030025.

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Gastrointestinal cancers represent a major cause of morbidity and mortality worldwide. A significant issue regarding the therapeutic management of these patients consists of metabolic disturbances and malnutrition. Nutritional deficiencies have a negative impact on both the death rates of these patients and the results of surgical or oncological treatments. Thus, current guidelines recommend the inclusion of a nutritional profile in the therapeutic management of patients with gastrointestinal cancers. The development of digestive endoscopy techniques has led to the possibility of ensuring the enteral nutrition of cancer patients without oral feeding through minimally invasive techniques and the avoidance of surgeries, which involve more risks. The enteral nutrition modalities consist of endoscopy-guided nasoenteric tube (ENET), percutaneous endoscopic gastrostomy (PEG), percutaneous endoscopic gastrostomy with jejunal tube extension (PEG-J), direct percutaneous endoscopic jejunostomy (DPEJ) or endoscopic ultrasound (EUS)-guided gastroenterostomy.
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12

K, Ghebouli, Bendjoudi K, Larkem H, Kecir MA und Belbekri M. „Video Assisted Thoracoscopy Talc Pleurodesis in the Management of Metastatic Pleural Effusion“. EAS Journal of Medicine and Surgery 5, Nr. 10 (24.11.2023): 197–201. http://dx.doi.org/10.36349/easjms.2023.v05i10.005.

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Introduction: Metastatic pleural effusion complicates many cancers and impairs patients' quality of life. In a palliative situation, the decision between thoracoscopy talc pleurodesis, tube chest, iterative punctures or abstention is difficult and often operator dependent. Materials and methods: We report a study of 87 patients with metastatic pleural effusion treated by video assisted thoracoscopy talc pleurodesis. Results: Breast cancer constitutes the primary site causing metastatic pleural effusion in approximately half of cases, followed by bronchopulmonary cancers and finally digestive cancers. The complete response rate in the short and medium term is very satisfactory. We did not report any complications apart from one case of empyema. Conclusion: video assisted thoracoscopy talc pleurodesis constitutes an interesting treatment for recurrence of metastatic pleural effusion.
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Vella-Boucaud, J., D. Papathanassiou, O. Bouche, A. Prevost, T. Lestra, J. Nardi, J. M. Perotin et al. „Fixations du tube digestif de découverte fortuite en TEP-TDM chez les patients suivis pour un cancer bronchopulmonaire“. Revue des Maladies Respiratoires 32 (Januar 2015): A123. http://dx.doi.org/10.1016/j.rmr.2014.10.639.

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14

Canard, J. M. „Prévention des complications des traitements endoscopiques des cancers superficiels du tube digestif supérieur et nécessité d’une surveillance étroite au-delà de cinq ans après la fin du traitement“. Acta Endoscopica 45, Nr. 4 (Juni 2015): 193–94. http://dx.doi.org/10.1007/s10190-015-0477-2.

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15

Seneviratne, Lasika, Steven Evans, Juvairiya Pulicharam, Nadir Arber und Jacob Kuint. „Discovery of a core-panel of markers for a blood-assay for cancer detection utilizing cfDNA methylation changes.“ Journal of Clinical Oncology 38, Nr. 15_suppl (20.05.2020): 1522. http://dx.doi.org/10.1200/jco.2020.38.15_suppl.1522.

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1522 Background: Cancer screening is limited to several cancers despite improved outcome A screening test should be acceptable, safe, and relatively inexpensive1 Tumors shed cfDNA to the blood where abundant tumor-specific methylation changes can be detected 1https://www.who.int/cancer/detection/variouscancer/en/. Methods: This is a prospective, multicenter, observational study under two protocols NCT04264767, NCT04264754. Plasma was collected from 1,255 subjects: 586 treatment-naïve cancer patients and 639 controls, in 21 sites and biobanks. Training set I (211 cases/99 controls) was used to select the 6 final markers for the core panel, training set II (200 controls) was used to lock the algorithm, and set the threshold to a score yielding specificity of 95%. The validation set (342 cases/310 controls) was performed utilizing the pre-specified algorithm and threshold. Plasma was separated from a single EDTA tube within 4 hours of blood draw. EpiCheck’s reagents and methylation-sensitive enzymes (Nucleix, Israel) were used for DNA extraction, digestion, and amplification in real-time PCR (ABI 7500 Fast Dx, Applied Biosystems). Results: Age was comparable but sex and smoking history were different (more women in cases, more smokers in controls). In the validation cohort twelve cancer types were included, with prominent representation of major cancer types (19% Breast, 14% colorectal and 21% lung) and stages I&II (56%). Specificity and sensitivity were maintained high at 94% and 62%. Highest sensitivity was demonstrated in GI cancers (77% colorectal, 83% esophageal, 100% gastric) and non-solid malignancies (83%). Sensitivity in early stage cancers (stages I, II & IIIA) was 71%, led by Sarcoma (83%) esophageal (76%) and colorectal (61%). Conclusions: This 6-marker blood-based methylation assay is a promising initial component in a future cancer screening test, generating significant signal in early cancers and utilizing simple and inexpensive PCR technology. Clinical trial information: NCT04264767, NCT04264754. [Table: see text]
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16

Boudghène-Stambouli, Frank, Gérard Schmutz und Denis Régent. „Tube digestif“. Journal de Radiologie 85, Nr. 9 (September 2004): 1280. http://dx.doi.org/10.1016/s0221-0363(04)76909-7.

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17

Boudghène, Franck, Jean-Michel Bruel und Catherine Ridereau-Zins. „Tube digestif“. Journal de Radiologie 86, Nr. 10 (Oktober 2005): 1295. http://dx.doi.org/10.1016/s0221-0363(05)75338-5.

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18

Piva, MT, V. Sieso, A. Christopoulou, S. Lumbroso, P. Perney, H. Mion und F. Blanc. „Intérêt de la phosphatase alcaline et de sa fraction H2 dans le diagnostic de métastases hépatiques d'un cancer du tube digestif“. La Revue de Médecine Interne 15 (Januar 1994): 140s. http://dx.doi.org/10.1016/s0248-8663(05)82728-6.

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19

Landolsi, A., I. Chabchoub, S. Limem, O. Gharbi, R. Chaafai, M. Hochlef, L. B. Fatma et al. „Les lymphomes primitifs du tube digestif (LPTD) dans le centre tunisien : étude anatomoclinique et résultats thérapeutiques à propos de 153 cas“. Bulletin du Cancer 97, Nr. 4 (April 2010): 435–43. http://dx.doi.org/10.1684/bdc.2010.1085.

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20

Verduijn, Peter G. „Late Health Effects of Radiation for Eustachian Tube Dysfunction: Previous Results and Ongoing Study in the Netherlands“. Otolaryngology–Head and Neck Surgery 115, Nr. 5 (November 1996): 417–21. http://dx.doi.org/10.1177/019459989611500510.

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To study the late health effects of nasopharyngeal radium irradiation, a nonconcurrent prospective study was conducted in The Netherlands. Exposed subjects ( n = 2510) were treated unilaterally with nasopharyngeal radium irradiation at five ear, nose, and throat clinics between 1945 and 1965 and followed up through February 1, 1985. Unexposed subjects ( n = 2199) were matched to treated patients according to clinic, year of birth, and first consultation within 5 years. No overall significant increase in cancer mortality was found. A statistically significant difference was noted only for cumulative all-site cancer incidence, with the exposed having twice as many verified cancers as the nonexposed. This excess risk was caused mainly by head and neck tumors and other tumors flung, digestive tract, and urogenital system). The relative risk for these specific sites, however, was not significantly different from 1.00. These findings corroborate the hypothesis that there is some risk of tumor induction involved with nasopharyngeal radium irradiation at the dose level applied to this population. Because of ongoing interest in this subject, I plan to extend the follow-up of the cohort through December 31, 1995, and I am studying the possibility of expanding the study population.
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21

Buscarini, Elisabetta. „Tube digestif: pour“. Acta Endoscopica 33, Nr. 1 (Februar 2003): 1–5. http://dx.doi.org/10.1007/bf03023666.

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22

Stines, Joseph. „Tube digestif irradié“. EMC - Radiologie et imagerie médicale - Abdominale - Digestive 15, Nr. 3 (1997): 1. https://doi.org/10.1016/s0246-0610(97)33315-5.

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23

Shrotriya, Shiva, Calvin Abro, Fawzi Abu Rous, Rosemary Trimmer, Mukta Sharma, Supratik Rayamajhi, Bassam N. Estfan und Declan Walsh. „Swallow screen and test in cancer patients.“ Journal of Clinical Oncology 37, Nr. 15_suppl (20.05.2019): e18288-e18288. http://dx.doi.org/10.1200/jco.2019.37.15_suppl.e18288.

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e18288 Background: Swallowing is a complex process with four phases. It initiates digestion and is essential for proper nutrition. Difficulty swallowing independently correlated with cancer survival. We retrospectively evaluated the prevalence and incidence of difficulty swallowing in an acute care palliative medicine unit. BMI and survival were also examined. Methods: Electronic Medical Records (EMR) 2010-2012 was reviewed. Assessment comprised of 3 steps: nurse survey on patient condition (coma, intubation, PEG/feeing tube, respiratory distress), screening questionnaire and clinical swallowing test. Change in BMI from the day of admission to discharge calculated. Survival calculated from EMR and Social Security Death Index. Results: N = 261 with cancer identified; 47% known metastases. The mean age (± SD) was 68 ± 13 years. 55% females. 71% Caucasians and 25% African Americans. It was common in lung, gastrointestinal (GI) and genitourinary (GU) cancers. Clinical swallowing test was indicated in 94%. Prevalence of difficulty swallowing = 6%. Incidence of difficulty swallowing = 21%. Change in Body Mass Index (BMI) from 26 ± 7 (Mean ± SD) to 26 ± 6 on admission to discharge respectively. Median (25th, 75th percentile) survival: 25(13, 62) days. Conclusions: Difficulty swallowing was common in lung, GI and GU cancers. The incidence of difficulty swallowing in acute care palliative medicine unit was 21% and prevalence 6%. 75% with difficulty swallowing identified by nurse’s initial survey, 19% through screening questionnaires and 6% clinical swallowing test. Pneumonia/respiratory and GI problems were common. Swallowing evaluation critical for comprehensive cancer care.
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Quilliot, Didier, Niasha Michot, Lucie Germain, Justine Krier, Anthony Lopez, Laurent Bresler, Ahmet Ayav, Aurélie Malgras und Phi-Linh Nguyen-Thi. „Feasibility, acceptability of enteral tube feeding and self-insertion of a nasogastric tube in the nutritional management of digestive cancers, impact on quality of life“. Clinical Nutrition 39, Nr. 6 (Juni 2020): 1785–92. http://dx.doi.org/10.1016/j.clnu.2019.07.017.

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Costache, M. I., Mihai Ioana, Sevastiţa Iordache, D. Ene, Cornelia Alexandra Costache und A. Săftoiu. „VEGF expression in pancreatic cancer and other malignancies: a review of the literature“. Romanian Journal Of Internal Medicine 53, Nr. 3 (01.09.2015): 199–208. http://dx.doi.org/10.1515/rjim-2015-0027.

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Abstract Angiogenesis is a crucial event for tumor growth and it is regulated predominantly by several different growth factors. Vascular endothelial growth factor protein family (VEGF) and its receptors are probably the most important tissue factors responsible for angioblast differentiation and tube formation. VEGF protein family currently comprises several members: VEGF (or VEGF-A), VEGF-B, VEGF-C and VEGF-D, VEGF-F, placental growth factor (PlGF), and their receptors VEGFR-1, VEGFR-2 and VEGFR-3. VEGF is a key angiogenic growth factor and its level of expression is a critical marker for detection of the angiogenic diseases. The potent role of VEGF in tumor angiogenesis has been widely described in the past decade, being expressed in most types of nondigestive and digestive cancers. VEGF family members play an important role in the development of pancreatic cancer (especially VEGF-A, VEGF-C, VEGF-D, VEGFR-1 and VEGFR-2). VEGF-A is the most specific and prominent angiogenic factor among all family members and VEGFR-2 is the most important receptor in evaluating the angiogenesis in pancreatic cancer. Thus, VEGF overexpression may be considered as a diagnostic marker and as a poor prognostic factor of the disease.
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Bogomoletz, Wladimir V. „Histopathologie du Tube Digestif“. American Journal of Surgical Pathology 12, Nr. 10 (Oktober 1988): 812. http://dx.doi.org/10.1097/00000478-198810000-00025.

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Faivre, Jamila, Christian Bréchot und Nicolas Moniaux. „Communication foie/tube digestif“. médecine/sciences 29, Nr. 11 (November 2013): 954–56. http://dx.doi.org/10.1051/medsci/20132911008.

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Gallix, Benoît. „IRM du tube digestif“. Journal de Radiologie 88, Nr. 10 (Oktober 2007): 1274. http://dx.doi.org/10.1016/s0221-0363(07)80656-1.

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Aubé, Christophe. „Imagerie du tube digestif“. Journal de Radiologie 88, Nr. 10 (Oktober 2007): 1449. http://dx.doi.org/10.1016/s0221-0363(07)81382-5.

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Adell, J. F., und S. Aufort. „Tumeur du tube digestif“. Journal de Radiologie 89, Nr. 10 (Oktober 2008): 1285. http://dx.doi.org/10.1016/s0221-0363(08)75827-x.

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Carbonnel, Franck. „Tube digestif et pancréas“. Gastroentérologie Clinique et Biologique 28, Nr. 3 (März 2004): 215–17. http://dx.doi.org/10.1016/s0399-8320(04)94885-3.

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Blayac, Paul-Marie, Nicolas Kessler, Alvian Lesnik, Patrice Taourel, Franc¸ois-Michel Lopez und Jean-Michel Bruel. „Traumatismes du tube digestif“. EMC - Radiologie et imagerie médicale - Abdominale - Digestive 1, Nr. 1 (Januar 2006): 1–7. http://dx.doi.org/10.1016/s1879-8527(06)74702-5.

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Regent, D., C. Balaj, F. Jausset, A. Oliver, C. Sellal-Aubriot und V. Croise-Laurent. „Perforations du tube digestif“. EMC - Radiologie et imagerie médicale - Abdominale - Digestive 7, Nr. 4 (Dezember 2012): 1–21. http://dx.doi.org/10.1016/s1879-8527(12)59309-3.

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Descos, L. „Cytomegalovirus et tube digestif“. Médecine et Maladies Infectieuses 18 (März 1988): 42–43. http://dx.doi.org/10.1016/s0399-077x(88)80092-1.

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Descos, L. „Cytomegalovirus et tube digestif“. Médecine et Maladies Infectieuses 18, Nr. 12 (Dezember 1988): 863–68. http://dx.doi.org/10.1016/s0399-077x(88)80242-7.

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Ruskoné-Fourmestraux, A. „Lymphomes du tube digestif“. EMC - Traité de médecine AKOS 8, Nr. 2 (April 2013): 1–7. http://dx.doi.org/10.1016/s1634-6939(13)62156-0.

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Adell, J. F., und S. Aufort. „Tumeur du tube digestif“. Journal de Radiologie 90, Nr. 10 (Oktober 2009): 1364. http://dx.doi.org/10.1016/s0221-0363(09)75391-0.

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Ruskoné-Fourmestraux, A., B. Fabiani und C. Thieblemont. „Lymphomes du tube digestif“. EMC - Gastro-entérologie 8, Nr. 1 (Januar 2013): 1–13. http://dx.doi.org/10.1016/s1155-1968(12)46614-7.

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Ruskoné-Fourmestraux, A., C. Thieblemont und B. Fabiani. „Lymphomes du tube digestif“. EMC - Hématologie 8, Nr. 2 (Mai 2013): 1–13. http://dx.doi.org/10.1016/s1155-1984(13)60050-3.

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Valette, P. J., und Y. Menard. „Tomodensitométrie du tube digestif“. Acta Endoscopica 27, Nr. 4 (Juli 1997): 351–53. http://dx.doi.org/10.1007/bf02968706.

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Regent, Denis, Clémence Balaj, François Jausset, Alexandre Oliver, Caroline Sellal-Aubriot und Valérie Croise-Laurent. „Perforations du tube digestif“. Feuillets de Radiologie 54, Nr. 1 (Februar 2014): 9–31. http://dx.doi.org/10.1016/j.frad.2014.01.002.

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Amatore, F., und E. Delaporte. „Peau et tube digestif“. EMC - Dermatologie 25, Nr. 2 (Mai 2023): 1–10. https://doi.org/10.1016/s0246-0319(22)43968-9.

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43

Blayac, Paul-Marie, Nicolas Kessler, Alvian Lesnik, Patrice Taourel, François-Michel Lopez und Jean-Michel Bruel. „Traumatismes du tube digestif“. EMC - Radiologie et imagerie médicale - Abdominale - Digestive 20, Nr. 4 (2002): 1–8. https://doi.org/10.1016/s0246-0610(02)00045-2.

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44

Palazzo, Laurent, Gilles Roseau, Jean Vitaux und Joseph-Antoine Paolaggi. „Endosonographie du tube digestif“. EMC - Gastro-entérologie 12, Nr. 2 (1995): 1. https://doi.org/10.1016/s1155-1968(95)09677-5.

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45

Agarwal, Shashi K. „Lifestyles and their Close Relationship with Gastrointestinal Diseases (Part I: Diet)“. East African Scholars Journal of Medical Sciences 5, Nr. 2 (18.02.2022): 49–57. http://dx.doi.org/10.36349/easms.2022.v05i02.005.

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The gastrointestinal tract (GI) is a continuous hollow twisting tube from the mouth to the anus. Its hollow organs include the mouth, esophagus, stomach, small intestine, large intestine, and anus. The liver, pancreas, and gallbladder (solid organs) are also considered part of the GI tract. The principal functions of the GI tract are digestion, absorption, excretion, and protection. Digestion and absorption occur primarily in the stomach and small intestine. Desiccation and compaction of waste occur in the large intestine. The waste products are then stored in the sigmoid colon and rectum before their elimination. The GI tract is influenced by several lifestyles, including the amount and the composition of the diet. The macronutrients and micronutrients in the diet, if prudent, are important for maintaining good GI health. However, unhealthy choices may cause or influence the development of GI pathology (such as esophageal reflux, peptic ulcer, inflammatory bowel disease, dietary intolerance, or even GI cancers). The lifestyle GI connection is reviewed in this two-part manuscript.
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Zarin, Bahare, Laleh Rafiee, Parnaz Daneshpajouhnejad und Shaghayegh Haghjooy Javanmard. „A review on the role of CAFs and CAF-derived exosomes in progression and metastasis of digestive system cancers“. Tumor Biology 43, Nr. 1 (18.08.2021): 141–57. http://dx.doi.org/10.3233/tub-200075.

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Cancers evolve as a result of the accelerated proliferation of cancer cells in a complicated, enriched, and active microenvironment. Tumor microenvironment (TME) components are the master regulators of any step of cancer development. The tumor microenvironment is composed of many cellular and noncellular components that contribute to the evolution of cancer cells. Cancer-associated fibroblasts (CAFs) are activated fibroblasts in the TME that implicate in tumor progression and metastasis dissemination through secretion of oncogenic factors which are carried to the secondary metastatic sites through exosomes. In this review, we aimed to assess the role of CAF-derived exosomes in TME construction and pre-metastatic niche formation in different cancers of the digestive system in order to better understand some important mechanisms of metastasis and provide possible targets for clinical intervention. This review article is divided into two thematic parts explaining the general mechanisms of pre-metastatic niche formation and metastasis and the role of CAF-derived exosomes in different digestive system cancers including colorectal, gastric, esophageal, pancreatic, and liver cancers.
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47

Maunoury, Vincent, Caroline Degrugillier-Chopinet und Brigitte Jude. „Malformations vasculaires du tube digestif“. Sang thrombose vaisseaux 22, Nr. 7 (September 2010): 383–88. http://dx.doi.org/10.1684/stv.2010.0506.

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48

Molkhou, P. „Allergie alimentaire et tube digestif“. Revue Française d'Allergologie 55, Nr. 7 (November 2015): 436–37. http://dx.doi.org/10.1016/j.reval.2015.10.002.

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49

Nahon, S., und Y. Bouhnik. „Vascularites, collagénoses et tube digestif“. EMC - Gastro-entérologie 1, Nr. 1 (Januar 2006): 1–6. http://dx.doi.org/10.1016/s1155-1968(04)27492-2.

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50

Baju, Alice, Xavier Causse, Xavier Coutouly, Fréderic Maitre, Patrick Michenet, Bernadette Berland-dai und Pascal Potier. „Schwannomes multiples du tube digestif“. Gastroentérologie Clinique et Biologique 30, Nr. 4 (April 2006): 632–35. http://dx.doi.org/10.1016/s0399-8320(06)73247-x.

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