Auswahl der wissenschaftlichen Literatur zum Thema „C - hetero“

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Zeitschriftenartikel zum Thema "C - hetero"

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Zhao, Yating, und Wujiong Xia. „Photochemical C–H bond coupling for (hetero)aryl C(sp2)–C(sp3) bond construction“. Organic & Biomolecular Chemistry 17, Nr. 20 (2019): 4951–63. http://dx.doi.org/10.1039/c9ob00244h.

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This review highlights the recent advances in photochemical (hetero)aryl C(sp2)–C(sp3) bond construction via C–H bond coupling such as (hetero)arylation of C(sp3)–H bonds and alkylation of (hetero)aryl C(sp2)–H bonds.
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Hucthagowder, Vishwanathan, Chelsea D. Mullins, Rekha Meyer, Rakesh Nagarajan, John F. DiPersio, Ravi Vij, Michael H. Tomasson und Shashikant Kulkarni. „Resequencing Analysis of the Human Candidate Ras and Receptor Tyrosine Kinase Gene Family In Multiple Myeloma“. Blood 116, Nr. 21 (19.11.2010): 301. http://dx.doi.org/10.1182/blood.v116.21.301.301.

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Abstract Abstract 301 Multiple myeloma (MM) is an incurable B-cell malignancy characterized by the clonal proliferation and accumulation of malignant plasma cells in the bone marrow. Despite the growing number of sequencing studies, the comprehensive view of somatic mutations in multiple myeloma is far from clear. One of the most frequently altered gene families in most human cancer is the Ras and the tyrosine kinase (TK) genes, which encode for important regulators of various signal transduction pathways. To uncover the somatic mutation profile of Ras gene and TKs in myeloma, we performed a systematic mutation screening from a selected group of 10 candidate genes in 42 primary myeloma patients. The candidate gene selections were based on the highly altered genes extracted from GEO data sets using Function Express, a data mining and viewer for microarray data. The sequencing of the entire gene region including the promoter and the 3`UTR was performed in the Genome sequencing center at Washington University medical center using the standard resequencing pipeline, from the design of the primers to data output. These data were analyzed with a clinical resequencing pipeline and visualized using the Mutation Viewer software (MV v5.1). We identified 24 nonsynonymous alterations in five genes (KRAS2, PIK3CA, INSR, LTK and MERTK) in our myeloma cohort (Table 1). In particular, we identified the previously reported pathogenic mutation in a KRAS gene and novel somatic mutations in the Kinase family (PIK3CA) that would be expected to cause structural changes. We assessed the frequency plots of the known variants and most but not all are significantly different from the normal data set. The overall results suggest that the germline genetic background besides the somatically acquired mutations may exert an important influence on the prognosis and outcome of the myeloma patient. Our genome-wide resequencing approach thus revealed previously known and novel oncogenic mutations in multiple myeloma, but its relevance needs to be considered in the context of other genetic abnormalities. Table 1: DNA alterations in candidate ras and TK genes in primary multiple myeloma Gene Gene IDa Nucleotide changeb Amino acid change Zygosityc PolyPhen COSMIC KRAS2 3845 c.35 G>A p.G12D Hetero P. Dam Yes KRAS2 3845 c.34 G>T, c.33 T>C p.G12C, A11A Hetero Benign Yes KRAS2 3845 c.183 A>C p.Q61H Hetero P. Dam Yes KRAS2 3845 c.186_194 del p.E62_Y64 Homo PIK3CA 5290 c.928 C>T p.R310C Hetero Yes PIK3CA 5290 c.1173 A>G p.I391M Hetero Benign INSR 3643 c.356 C>T p.A119V Hetero INSR 3643 c.2243 C>T p.S748L Hetero INSR 3643 c.3034 G>A p.V1012M Hetero P. Dam LTK 4058 c.125 G>A p.R42Q Hetero Benign LTK 4058 c.680 C>T p.P227L Hetero LTK 4058 c.728 G>A p.R243Q Hetero LTK 4058 c.1603 G>A p.D535N Hetero MERTK 10461 c.60 A>T p.R20S Hetero Benign MERTK 10461 c.1552 A>G p.I518V Hetero, Homo Benign MERTK 10461 c.1397 G>A p.R466K Hetero, Homo Benign MERTK 10461 c.353 G>A p.S118N Hetero, Homo Benign MERTK 10461 c.2608 G>A p.V870I Hetero Benign MERTK 10461 c.844 G>A p.A282T Hetero Benign MERTK 10461 c.1493 A>G, c.1494 C>T p.N498S Hetero Benign MERTK 10461 c.878 G>A p.R293H Hetero Benign MERTK 10461 c.2593 C>T p.R865W Hetero P. Dam MERTK 10461 c.2069 C>T p.T690I Hetero Benign MERTK 10461 c.2467 G>C p.E823Q Hetero Benign a Gene ID at National center for biotechnology information (http://www.ncbi.nlm.nih.gov/sites/entrez) b del., deletion c Homo, homozygous; hetero, heterozygous Disclosures: No relevant conflicts of interest to declare.
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Choy, Pui Ying, Shun Man Wong, Anant Kapdi und Fuk Yee Kwong. „Recent developments in palladium-catalysed non-directed coupling of (hetero)arene C–H bonds with C–Z (Z = B, Si, Sn, S, N, C, H) bonds in bi(hetero)aryl synthesis“. Organic Chemistry Frontiers 5, Nr. 2 (2018): 288–321. http://dx.doi.org/10.1039/c7qo00693d.

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This review article describes the palladium-catalysed non-directed coupling of (hetero)arene C–H bonds with C(Ar)–Z (Z = B, Si, Sn, S, N, C, H) bonds for facile bi(hetero)aryl synthesis in the past 10 years.
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Xiao, Fang, Jin-Hong Lin, Fei Hao, Xing Zheng, Yu Guo und Ji-Chang Xiao. „Visible light mediated C–H trifluoromethylation of (hetero)arenes“. Organic Chemistry Frontiers 9, Nr. 7 (2022): 1982–85. http://dx.doi.org/10.1039/d2qo00067a.

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Described herein is an efficient visible light mediated trifluoromethylation of (hetero)arenes using TFSP as a CF3 source. Various aromatic (hetero)cycles could undergo this protocol to give the corresponding trifluoromethylation products.
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Ran, You, Yudong Yang, Huansha You und Jingsong You. „RhCl3-Catalyzed Oxidative C–H/C–H Cross-Coupling of (Hetero)aromatic Sulfonamides with (Hetero)arenes“. ACS Catalysis 8, Nr. 3 (30.01.2018): 1796–801. http://dx.doi.org/10.1021/acscatal.7b04298.

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Verrier, Cécile, Pierrik Lassalas, Laure Théveau, Guy Quéguiner, François Trécourt, Francis Marsais und Christophe Hoarau. „Recent advances in direct C–H arylation: Methodology, selectivity and mechanism in oxazole series“. Beilstein Journal of Organic Chemistry 7 (29.11.2011): 1584–601. http://dx.doi.org/10.3762/bjoc.7.187.

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Catalytic direct (hetero)arylation of (hetero)arenes is an attractive alternative to traditional Kumada, Stille, Negishi and Suzuki–Miyaura cross-coupling reactions, notably as it avoids the prior preparation and isolation of (hetero)arylmetals. Developments of this methodology in the oxazole series are reviewed in this article. Methodologies, selectivity, mechanism and future aspects are presented.
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Liu, Yahu, Xuebin Liao und Lu Hu. „Recent Progress in Methylation of (Hetero)Arenes by Cross-Coupling or C–H Activation“. Synlett 29, Nr. 04 (05.02.2018): 375–82. http://dx.doi.org/10.1055/s-0037-1609093.

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Owing to the ‘magic methyl effect’ on a compound’s physical and biological properties, methylation is a strategy frequently used by medicinal chemists in structure–activity relationship studies or in lead optimization. This article highlights the most recent reported methods for the direct methylation of (hetero)arenes, which mainly involve either C–H functionalization or cross-coupling of methylating reagents with (hetero)aryl halides. Methylation of C–H bonds of (hetero)-arenes, which is atom economical, has been explored by several research groups in recent years. Given the unmatchable availability of (hetero)aryl halides, we believe that Ni-catalyzed methylation using iodomethane or deuterated iodomethane as the methyl source is one of the most convenient methods.
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Pahovnik, David, Uroš Uršič, Uroš Grošelj, Anton Meden, Jurij Svete und Branko Stanovnik. „Synthesis of Dimethyl 1-(Hetero)aryl-4-oxo-1,4-dihydropyridazine- 3,5-dicarboxylates from Dimethyl 3-Oxopentane-1,5-dioates“. Zeitschrift für Naturforschung B 63, Nr. 4 (01.04.2008): 407–14. http://dx.doi.org/10.1515/znb-2008-0407.

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AbstractDimethyl 3-oxopentane-1,5-dioate (dimethyl acetone-1,3-dicarboxylate) (1) was transformed first with (hetero)arenediazonium salts 3a - j into dimethyl 2-[(hetero)arylhydrazono]pentane-1,5-dioates 4a - j followed by reaction with N,N-dimethylformamide dimethylacetal (DMFDMA) to afford, without isolation of intermediates 5a - j, dimethyl 1-(hetero)aryl-4-oxo-1,4-dihydropyridazine-3,5- dicarboxylates 6a - j. An alternative method represents transformation of 1 with DMFDMA into dimethyl 2-[(dimethylamino)methylidene]-3-oxopentane-1,5-dioate (7) followed by treatment with (hetero)arenediazonium salts 3a - c, j to give pyridazine derivatives 6a - c,j.
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Arani, A. Ghorbanpour, und R. Kolahchi. „Exact solution for nonlocal axial buckling of linear carbon nanotube hetero-junctions“. Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science 228, Nr. 2 (25.03.2013): 366–77. http://dx.doi.org/10.1177/0954406213483647.

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CNT hetero-junctions offer the possibility of being used in micro-electromechanical systems and nano-electromechanical systems. However, in the present work, nonlocal axial buckling analysis of linear CNT hetero-junctions based on Euler–Bernoulli beam (EBB) model is investigated. In order to mathematically model a linear CNT hetero-junction, a CNT with two segments is considered. The constitutive equations are derived based on the Eringen's theory for various boundary conditions, namely clamped–clamped (C–C), clamped–pinned (C–P) and pinned–pinned (P–P). An analytical approach is applied to obtain the dimensionless buckling load of the CNT hetero-junctions. A detailed parametric study is conducted to elucidate the influences of the small-scale coefficient, homogeneity parameter, boundary conditions and CNT length of each segment on the axial buckling of the linear CNT hetero-junctions. The results indicate that the length of each segment and homogeneity parameter have a significant effect on the buckling load of the CNT hetero-junctions and should therefore be considered in its optimum design. Furthermore, the results are in good agreement with the previous researches.
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Gui, Yong-Yuan, Li-Li Liao, Liang Sun, Zhen Zhang, Jian-Heng Ye, Guo Shen, Zhi-Peng Lu, Wen-Jun Zhou und Da-Gang Yu. „Coupling of C(sp3)–H bonds with C(sp2)–O electrophiles: mild, general and selective“. Chemical Communications 53, Nr. 6 (2017): 1192–95. http://dx.doi.org/10.1039/c6cc09685a.

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Dissertationen zum Thema "C - hetero"

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Devaraj, Karthik. „Ruthenium-catalyzed C-H Functionalization of (Hetero)arenes“. Doctoral thesis, Uppsala universitet, Organisk kemi, 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-310998.

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This thesis concerned about the Ru-catalyzed C-H functionalizations on the synthesis of 2-arylindole unit, silylation of heteroarenes and preparation of aryne precursor. In the first project, we developed the Ru-catalyzed C2-H arylation of N-(2-pyrimidyl) indoles and pyrroles with nucleophilic arylboronic acids under oxidative conditions. Wide variety of arylboronic acids afforded the desired product in excellent yield regardless of the substituents or functional group electronic nature. Electron-rich heteroarenes are well suited for this method than electron-poor heteroarenes. Halides such as bromide and iodide also survived, further derivatisation of the halide is shown by Heck alkenylation. In order to find catalytic on-cycle intermediate extensive mechanistic experiments have been carried out by preparing presumed ruthenacyclic complexes and C-H/D exchange reactions. It suggested that para-cymene ligand is not present in the catalytic on-cycle intermediate and we suspect that metalation occurs with electrophilic ruthenium center via SEAr mechanism. In the second project, we developed the Ru-catalyzed silylation of gramine, tryptamine and their congeners using silanes as coupling partner. The transformation worked well with many different silanes. Regarding directing group, nitrogen atom containing directing groups are more favoured than the oxygen containing directing groups. Wide range of gramines and tryptamines also yielded the desired product in poor to excellent yield. At higher temperature, albeit in low yield, undirected silylation occurred. In order to get some insights about the reaction pathway of the silylation C-H/D exchange experiments were performed, and it revealed the possibility of C4-H activation of gramines by an electron rich metal- Si-H/D experiments showed Si-H activation by Ru is easy. In the final project, we presented the closely related aryne precursors from arylboronic acids via Ru-catalyzed C-H silylation of arylboronates and their selective oxidation. Worthy of note, the aryne capture products obtained from arylboronic acids in a single purification.
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Subba, Raju. „Studies on the reactions of C - hetero bond formation“. Thesis, University of North Bengal, 2015. http://ir.nbu.ac.in/handle/123456789/1854.

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Saha, Bittu. „Development of Novel methodologies for the construction of c-hetero bond“. Thesis, University of North Bengal, 2018. http://ir.nbu.ac.in/handle/123456789/2823.

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Li, Haoran. „Pd-catalyzed C-H bond functionalizations of (hetero)arenes and alkenes : A one step access to poly(hetero)aromatics and styrene derivatives“. Thesis, Rennes, Ecole nationale supérieure de chimie, 2020. http://www.theses.fr/2020ENCR0068.

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Afin d'expliquer le contexte de mon travail de recherche, j'ai résumé dans le premier chapitre des informations mécanistiques générales sur l'arylation des liaisons C-H catalysée par le palladium et j'ai détaillé certains travaux sur l'arylation directe en relation avec mes travaux. Mes objectifs étaient d'étudier la réactivité de nouvelles unités synthétiques permettant l'accès direct à des composés bi-(hétéro)aryls ou à des dérivés du styrène. Ensuite, dans les chapitres 2 à 6, j'ai résumé mes travaux de recherche. J'ai étudié l’arylation directes en C2 du Methoxsalen par des chlorures de benzènesulfonyle, ainsi que la diarylation en C2,C3 en utilisant des bromures d'aryle catalysée par le palladium. Ces résultats sont résumés dans le chapitre 2. Ensuite, j'ai montré que la réaction d'arylation directe catalysée par le palladium permet d'accéder facilement à des dérivés de la Ticlopidine arylés en position C5 du cycle thiényle en une seule étape. Ces résultats sont décrits dans le chapitre 3. Dans le chapitre 4, nous avons étudié la réactivité du Diflufénican qui contient un cycle 1,3- difluorobenzène et une unité pyridine en utilisant la catalyse au ruthénium et au palladium. Dans des conditions appropriées, deux liaisons C-H différentes du Diflufénican peuvent être arylées. Dans le chapitre 5, j'ai utilisé différentes sources d’aryle pour fonctionnaliser les positions C10 et C11 des dibenzo[b,f]azépines. Grâce à ces réactions, une grande diversité de groupes fonctionnels a été introduite sur les dérivés de dibenzo[b,f]azépines. Enfin, dans le chapitre 6, j’ai décrit la première méthode permettant de préparer des dérivés de la Cyproheptadine C10-arylés
In order to explain the background of my research work, in the first chapter, I summarized general mechanistic information on palladium-catalyzed C-H bond arylation and detailed some literature on direct arylation related to my research work. My objectives were to study the reactivity of new synthetic units allowing the straightforward access to bi-(hetero)aryls compounds or styrene derivatives using aryl halides or benzenesulfonyl chloride derivatives as the aryl-sources. Then, in the chapters 2-6, I summarized my research work. I studied the regiocontrolled palladium-catalyzed direct C2-arylations of Methoxsalen using benzenesulfonyl chlorides and C2,C3-diarylations using aryl bromides as the aryl sources. These results are summarized in the chapter 2. Then, I found that Pd-catalyzed direct arylation reaction allows the easy access to Ticlopidine derivatives arylated at the C5-position of the thienyl ring in one step. These results are reported in the chapter 3. In the chapter 4, we studied the reactivity of Diflufenican which contains a 1,3-difluorobenzene ring and a pyridine unit using Ru and Pd catalysis. Under appropriate conditions, two different C-H bonds of Diflufenican could be arylated. In the chapter 5, I employed different aryl sources to functionalize the C10- and C11-positions of dibenzo[b,f]azepines, and obtained asymmetric products. Through these reactions, a wide diversity of functional group were introduced on the dibenzo[b,f]azepine derivatives. Finally, in the Chapter 6, I report the first method allowing to prepare C10-arylated Cyproheptadine derivatives
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Zhao, Liqin. „Palladium-catalyzed direct arylation via sp² and sp³ C-H activation of hetero(aromatics) and hydrocarbons for C-C bond formation“. Thesis, Rennes 1, 2014. http://www.theses.fr/2014REN1S038/document.

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Au cours de cette thèse, nous nous sommes intéressés à l'activation de liaisons sp² et sp³ C-H catalysée par le palladium pour la préparation d'(hétéro)aryl-aryles et de biaryles. Cette méthode est considérée comme attractive pour l'environnement par rapport aux méthodes classiques, tels que Suzuki, Heck, ou Negishi. Tout d'abord, nous avons décrit que la C2-arylation directe de benzothiophènes peut être effectuée par un catalyseur du palladium en l'absence de ligand phosphine avec une grande sélectivité. Nous avons également démontré qu'il est possible d'activer les positions C2 et C5 de pyrroles pour accéder en une seule étape a des 2,5-diarylpyrroles. Des 2,5-diarylpyrroles non-symétriques ont été formés par arylation séquentielle en C2 suivie par une arylation en C5. Nous avons également étudié la réactivité de polychlorobenzenes pour l'activation de liaisons C-H catalysé au palladium. Nous avons finalement étudié l'activation sp² et sp³ sélective catalysé au palladium de liaisons C-H du guaiazulene. La sélectivité de la réaction dépend du solvant et de la base : C2-arylation (KOAc en éthylbenzène), C3-arylation (KOAc dans le DMAc) et C4-Me arylation (CsOAc/K₂CO₃ dans le DMAc). Grâce à cette méthode, une liaison sp³ C-H peu réactive a été activée
During this thesis, we were interested in the sp² and sp³ C-H bond activation catalyzed by palladium catalysts for the preparation of (hetero)aryl-aryls and biaryls. This method is considered as cost effective and environmentally attractive compared to the classical couplings such as Suzuki, Heck, or Negishi. First we described the palladium-catalyzed direct C2-arylation of benzothiophene in the absence of phosphine ligand with high selectivity. We also demonstrated that it is possible to active both C2 and C5 C-H bonds for access to 2,5-diarylated compounds in one step, and also to non-symmetrically substituted 2,5-diarylpyrroles via sequential C2 arylation followed by C5 arylation. We also studied the reactivity of polychlorobenzenes via palladium-catalyzed C-H activation. We finally examined the palladium-catalysed selective sp² and sp³ C-H bond activation of guaiazulene. The selectivity depends on the solvent and base: sp² C2-arylation (KOAc in ethylbenzene), sp² C3-arylation (KOAc in DMAc) and sp³ C4-Me arylation (CsOAc/K₂CO₃ in DMAc). Through this method, a challenging sp³ C-H bond was activated
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Öhlenschläger, Kim K. [Verfasser], und C. [Akademischer Betreuer] Barner-Kowollik. „Hetero Diels-Alder Reactions in Material Science / Kim K. Öhlenschläger. Betreuer: C. Barner-Kowollik“. Karlsruhe : KIT-Bibliothek, 2014. http://d-nb.info/1082294411/34.

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Kirchberg, Sylvia [Verfasser]. „Palladium-katalysierte C-H-Arylierungen von (Hetero)-Arenen mit Arylboronsäuren und TEMPO / Sylvia Kirchberg“. München : Verlag Dr. Hut, 2011. http://d-nb.info/1017353379/34.

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Sala, Fernanda Angélica. „Estudo da interação entre domínios C-terminais de septinas humanas: implicação na formação e estabilidade do filamento“. Universidade de São Paulo, 2015. http://www.teses.usp.br/teses/disponiveis/75/75133/tde-10082015-140053/.

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Septinas compreendem uma conservada família de proteínas de ligação a nucleotídeo de guanina e formação de heterofilamentos. Em termos estruturais, elas possuem uma organização comum: um domínio GTPase central, uma região N-terminal e um domínio C-terminal, este último é predito para formar estruturas em coiled coil. Atualmente, o heterocomplexo de septinas humanas (SEPT2/SEPT6/SEPT7) mais bem caracterizado revela a importância do domínio GTPase na formação do filamento, todavia a ausência de densidade eletrônica para os domínios C-terminais faz com que sua função permaneça obscura. Estudos com septinas de mamíferos, e de outros organismos como C. elegans e S. cerevisea sugerem que alguns grupos de septinas (por exemplo, II e IV em mamíferos) interagem através de seus domínios C-terminais, e estes poderiam atuar de modo determinante para a montagem correta do filamento. Assim, o presente projeto objetivou estudar a afinidade homo/heterotípicas para os domínios C-terminais das septinas humanas dos grupos II (SEPT6C/8C/10C/11C) e IV (SEPT7C), investigando se esses domínios contribuem para preferência das septinas interagirem com proteínas de grupos distintos durante a formação do heterofilamento. Os domínios C-terminais foram expressos em E. coli e purificados. Foram conduzidos estudos de ultracentrifugação analítica e espectropolarimetria de dicroísmo circular, que permitiram identificar maior afinidade e estabilidade da associação heterotípica comparada à homotípica. Foram obtidas constantes de dissociação aparente para homodímeros em torno de baixo µM, enquanto que para heterodímeros os dados já existentes no grupo revelaram constante de dissociação na ordem de nM. Para entender os fatores no nível atômico responsáveis pela significativa predileção na interação entre os domínios C-terminais dos grupos II e IV foram realizados estudos utilizando modelagem e análise das sequências primárias. As análises sugerem a presença de um alto número de resíduos carregados na posição a do coiled coil como responsável pela seletividade. Consequentemente, o heterodímero seria favorecido em virtude do menor efeito repulsivo proveniente do intercalamento dos resíduos carregados em a. Desse modo, os resultados indicaram a atuação decisiva ou cooperativa dos domínios C-terminais na organização preferencial das septinas durante a formação do filamento, favorecendo a interface NC entre septinas dos grupos II e IV.
Septins comprise a conserved protein family that binds guanidine nucleotide and forms heterofilaments. In structural terms they have a common organization: a central GTPase domain, a N-terminal domain and a C-terminal domain, this last one is predicted to form coiled coil structures. Currently, the human septin heterocomplex best characterized (SEPT2/SEPT6/SEPT7) reveals the importance of the GTPase domain in filament assembly, however the absence of electron density for the C-terminal domains makes its function still unknown. Studies with mammals septins, and of others organisms like C. elegans and S. cerevisea suggests that some septins groups (e.g. II e IV in mammals) interact via its C-terminal domains and this could act in a determinative way to correct filament assembly. In this way, this project aimed to study the homo/heterotypical affinity for the C-terminal domains of human septins belonging to groups II (SEPT6C/8C/10C/11C) e IV (SEPT7C), investigating whether this domain contributes with the preference of septins to interact with proteins of different groups during assembly of the heterofilament. The C-terminal domains were expressed in E. coli and purificated. It was carried out studies using analytical ultracentrifugation and circular dichroism spectropolarimetry tecniques which allowed identification of major affinity and stability in the heterotypical association compared to homotypical. It was measured apparent dissociation constants for homodimers of low µM range while for heterodimers our group\'s data shows dissociation constants in the nM range. To understand at atomic level the factors responsible for this significant preference in the C-terminal domains interaction between groups II and IV was performed molecular modelling studies and analysis of the primary sequence. These analysis suggests the presence of a high number of charged residues in position a of the coiled coil as responsible for selectivity. Consequently, the heterodimer would be therefore favoured because of the minor repulsive effect coming from the staggered of charged residues in a. Thus, these results indicate the crucial or cooperative action of C-terminal domains in preferential organization of septins during filament assembly, favouring the NC interface between septins of groups II and IV.
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Clouston, Laurel L. „The design and synthesis of C¦3 symmetric ligands for lanthanide Lewis acid catalysis of the inverse demand hetero Diels-Alder reaction“. Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk2/ftp02/NQ37336.pdf.

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O'Connor, Sean M. J. „Application of Tridentate Schiff Base Chromium (III) Complex Catalysts Towards the Total Synthesis of (-)- Lasonolide A and C-Disaccharide Mimics“. Thesis, Griffith University, 2012. http://hdl.handle.net/10072/366217.

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This thesis describes the synthetic studies performed utilizing tridentate Schiff base Cr(III) complex catalysts towards the total synthesis of ()-lasonolide A resulting in the completion of synthetic efforts towards the C17-C25 segment. Further summarization is also given on completion of the C7-C16 segment and an overview of future directions toward to the total synthesis of ()-lasonolide A. Both tetrahydropyrans C7-C11 and C19-C23 were to be constructed utilising an asymmetric hetero-Diels–Alder protocol involving Jacobsen’s hetero-Diels–Alder catalyst providing a means to generate a number of the desired stereocentres simultaneously in each ring system, followed by novel macrolide formation using ruthenium catalysts for metathesis olefination and Alder-ene chemistry. Jacobsen's hetero-Diels–Alder catalyst has also been utilised to generate C-disacharide linked precursors under diastereolective control in an effort to generate stereospecific 13 linked disaccharides.
Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
School of Biomolecular and Physical Sciences
Science, Environment, Engineering and Technology
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Bücher zum Thema "C - hetero"

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Rodd, E. H. Rodd's Chemistry of Carbon Compounds: Heterocyclic Compounds, Part C 5 Membered Heterocyclic Compounds With 2 Hetero Atoms in the Ring (Rodd's Chemistry of Carbon Compounds 2nd Edition). 2. Aufl. Elsevier Science Ltd, 1986.

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2

Ansell, Martin F. Supplements to the 2nd Edition of Rodd's Chemistry of Carbon Compounds : Heterocyclic Compounds : Part C: Five-Membered Heterocyclic Compounds with Two Hetero-Atoms in the Ring from Groups V and/or VI of the Periodic Table. Part D: Five-Membered Heterocyclic Compounds with More than Two Hetero-Atoms in the Ring. Not Avail, 1994.

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Buchteile zum Thema "C - hetero"

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Vopsaroiu, M., V. Kuncser, J. Bartolome, V. M. Meriacre, K. I. Turta, I. Prisecaru und G. Filoti. „Mössbauer and magnetic evidence for spin frustration in hetero-trinuclear clusters“. In Hyperfine Interactions (C), 213–16. Dordrecht: Springer Netherlands, 2002. http://dx.doi.org/10.1007/978-94-010-0281-3_53.

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Gang, Peng, Wang Xiaojing, Tang Pengju, Zhou Wenli und Yu Jun. „Simulation and Optimization of A-Si:H/C-Si Hetero-Junction Solar Cells“. In Proceedings of ISES World Congress 2007 (Vol. I – Vol. V), 1159–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2008. http://dx.doi.org/10.1007/978-3-540-75997-3_230.

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3

Gupta, Aniket, Sreedhar Gundekari und Sukalyan Bhadra. „C(sp3)–H Bond Hetero-functionalization of Aliphatic Carboxylic Acid Equivalents Enabled by Transition Metals“. In Catalysis for Clean Energy and Environmental Sustainability, 383–427. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-65017-9_13.

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4

Deka, Himangshu, Arun Kumar Sunaniya und Pratima Agarwal. „A Numerical Study on a c-Si(P) Substrate-Based Homo-Hetero Junction Solar Cell“. In Sustainable Energy Generation and Storage, 91–99. Singapore: Springer Nature Singapore, 2023. http://dx.doi.org/10.1007/978-981-99-2088-4_7.

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Cabezas-Gómez, Luben, Hélio Aparecido Navarro und José Maria Saíz-Jabardo. „Computational Code HETE (Standard C Programming Language)“. In SpringerBriefs in Applied Sciences and Technology, 63–67. Cham: Springer International Publishing, 2014. http://dx.doi.org/10.1007/978-3-319-09671-1_5.

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Hemingway, Richard W., Seiji Ohara, Jan P. Steynberg, E. Vincent Brandt und Daneel Ferreira. „C-H Hetcor NMR Studies of Proanthocyanidins and their Derivatives“. In Plant Polyphenols, 321–37. Boston, MA: Springer US, 1992. http://dx.doi.org/10.1007/978-1-4615-3476-1_18.

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Liu, B., C. Renaud, J. Kowynia, K. K. Nelson, E. Roudachevski, D. Snyder, J. Timar und K. V. Honn. „Activation Of Protein Kinase C by 12(S)-HETE: Role in Tumor Cell Metastasis“. In Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury, 629–34. Boston, MA: Springer US, 1993. http://dx.doi.org/10.1007/978-1-4615-3520-1_123.

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Tang, Dean G., und Kenneth V. Honn. „Role of Protein Kinase C and Phosphatases in 12(S)-Hete-Induced Tumor Cell Cytoskeletal Reorganization“. In Advances in Experimental Medicine and Biology, 349–61. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4615-5325-0_48.

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9

Ishihara, K., und A. Sakakura. „Hetero-Diels–Alder Reactions“. In Stereoselective Pericyclic Reactions, Cross Coupling, and C—H and C—X Activation, 1. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-203-00060.

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Ishihara, K., und A. Sakakura. „Enantioselective Hetero-Diels–Alder Reactions of Carbonyl Compounds“. In Stereoselective Pericyclic Reactions, Cross Coupling, and C—H and C—X Activation, 1. Georg Thieme Verlag KG, 2011. http://dx.doi.org/10.1055/sos-sd-203-00061.

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Konferenzberichte zum Thema "C - hetero"

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Hun-Soo Kim, Chang-Ho Lee, Doo-Bong Lee, Se-Young Oh und Jeong-Woo Choi. „Bio electroluminescent device composed of cytochrome c/chlorophyll a hetero-structure“. In 2006 IEEE Nanotechnology Materials and Devices Conference. IEEE, 2006. http://dx.doi.org/10.1109/nmdc.2006.4388762.

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Kunishima, I., K. Suguro, T. Aoyama und J. Matsunaga. „Homogeneous Hetero-Epitaxial NiSi2 Formation on (100)Si“. In 1990 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 1990. http://dx.doi.org/10.7567/ssdm.1990.c-10-7.

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Choi, Sang H., und Adam J. Duzik. „Rhombohedral super hetero epitaxy of cubic SiGe on trigonal c-plane sapphire“. In 2017 IEEE Photonics Society Summer Topical Meeting Series (SUM). IEEE, 2017. http://dx.doi.org/10.1109/phosst.2017.8012670.

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Jeong-Woo Choi, Doo-Bong Lee und Bumhwan Lee. „Rectified photocurrent of biophodiode composed of cytochrome c/chlorophyll a hetero-structure“. In 2006 IEEE Nanotechnology Materials and Devices Conference. IEEE, 2006. http://dx.doi.org/10.1109/nmdc.2006.4388761.

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Tagmatarchis, Nikos. „Hetero- and homo- [70] fullerene dimers: (C[sub 69]N)[sub 2] and (C[sub 70])[sub 2]“. In ELECTRONIC PROPERTIES OF MOLECULAR NANOSTRUCTURES: XV International Winterschool/Euroconference. AIP, 2001. http://dx.doi.org/10.1063/1.1426814.

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Schmidt, M., H. Angermann, E. Conrad, L. Korte, A. Laades, K. Maydell, Ch Schubert und R. Stangl. „Physical and Technological Aspects of a-Si:H/c-Si Hetero-Junction Solar Cells“. In 2006 IEEE 4th World Conference on Photovoltaic Energy Conference. IEEE, 2006. http://dx.doi.org/10.1109/wcpec.2006.279722.

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Rusop, M., Mohamad Rusop und Tetsuo Soga. „Photovoltaic Characteristics of Fabricated Carbon Based P-C∕N-Si Hetero-Junction Solar Cells“. In NANOSCIENCE AND NANOTECHNOLOGY: International Conference on Nanoscience and Nanotechnology—2008. AIP, 2009. http://dx.doi.org/10.1063/1.3160226.

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Ueda, Koji, Yuichiro Ando, Mamoru Kumano, Taizoh Sadoh, Kazumasa Narumi, Yoshihito Maeda und Masanobu Miyao. „Atomically Controlled Hetero-Epitaxy of DO3-type Fe3Si on Ge(111) Substrate“. In 2007 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 2007. http://dx.doi.org/10.7567/ssdm.2007.c-2-1.

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Shen, G. D., D. X. Xu, M. Willander und G. V. Hansson. „Multi-step Bidirectional NDR Characteristics in Si/Si1-xGex/Si Double Hetero-Structures“. In 1988 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 1988. http://dx.doi.org/10.7567/ssdm.1988.c-3-2.

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10

Zhang, G., K. Tateno, H. Gotoh und T. Sogawa. „InAsP-InAs-InAsP hetero-nanowires grown via the self-assisted vapor-liquid-solid mode“. In 2012 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 2012. http://dx.doi.org/10.7567/ssdm.2012.c-2-2.

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