Auswahl der wissenschaftlichen Literatur zum Thema „BML Home Set“

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Zeitschriftenartikel zum Thema "BML Home Set"

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Tay, Noel Nuo Wi, János Botzheim und Naoyuki Kubota. „Weighted Constraint Satisfaction for Smart Home Automation and Optimization“. Advances in Artificial Intelligence 2016 (23.11.2016): 1–15. http://dx.doi.org/10.1155/2016/2959508.

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Automation of the smart home binds together services of hardware and software to provide support for its human inhabitants. The rise of web technologies offers applicable concepts and technologies for service composition that can be exploited for automated planning of the smart home, which can be further enhanced by implementation based on service oriented architecture (SOA). SOA supports loose coupling and late binding of devices, enabling a more declarative approach in defining services and simplifying home configurations. One such declarative approach is to represent and solve automated planning through constraint satisfaction problem (CSP), which has the advantage of handling larger domains of home states. But CSP uses hard constraints and thus cannot perform optimization and handle contradictory goals and partial goal fulfillment, which are practical issues smart environments will face if humans are involved. This paper extends this approach to Weighted Constraint Satisfaction Problem (WCSP). Branch and bound depth first search is used, where its lower bound is estimated by bacterial memetic algorithm (BMA) on a relaxed version of the original optimization problem. Experiments up to 16-step planning of home services demonstrate the applicability and practicality of the approach, with the inclusion of local search for trivial service combinations in BMA that produces performance enhancements. Besides, this work aims to set the groundwork for further research in the field.
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Kelley, George A., Kristi S. Kelley und Wendy M. Kohrt. „Exercise and Bone Mineral Density in Premenopausal Women: A Meta-Analysis of Randomized Controlled Trials“. International Journal of Endocrinology 2013 (2013): 1–16. http://dx.doi.org/10.1155/2013/741639.

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Objective. Examine the effects of exercise on femoral neck (FN) and lumbar spine (LS) bone mineral density (BMD) in premenopausal women.Methods. Meta-analysis of randomized controlled exercise trials ≥24 weeks in premenopausal women. Standardized effect sizes (g) were calculated for each result and pooled using random-effects models,Zscore alpha values, 95% confidence intervals (CIs), and number needed to treat (NNT). Heterogeneity was examined usingQandI2. Moderator and predictor analyses using mixed-effects ANOVA and simple metaregression were conducted. Statistical significance was set atP≤0.05.Results. Statistically significant improvements were found for both FN (7g's, 466 participants,g=0.342, 95% CI=0.132, 0.553,P=0.001,Q=10.8,P=0.22,I2=25.7%,NNT=5) and LS (6g's, 402 participants,g=0.201, 95% CI=0.009, 0.394,P=0.04,Q=3.3,P=0.65,I2=0%,NNT=9) BMD. A trend for greater benefits in FN BMD was observed for studies published in countries other than the United States and for those who participated in home versus facility-based exercise. Statistically significant, or a trend for statistically significant, associations were observed for 7 different moderators and predictors, 6 for FN BMD and 1 for LS BMD.Conclusions. Exercise benefits FN and LS BMD in premenopausal women. The observed moderators and predictors deserve further investigation in well-designed randomized controlled trials.
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Manna, Dipankar, Xiuhua Wang und N. Patrick Higgins. „Mu and IS1 Transpositions Exhibit Strong Orientation Bias at the Escherichia coli bgl Locus“. Journal of Bacteriology 183, Nr. 11 (01.06.2001): 3328–35. http://dx.doi.org/10.1128/jb.183.11.3328-3335.2001.

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ABSTRACT The region upstream of the Escherichia coli bgloperon is an insertion hot spot for several transposons. Elements as distantly related as Tn1, Tn5, and phage Mu home in on this location. To see what characteristics result in a high-affinity site for transposition, we compared in vivo and in vitro Mu transposition patterns near the bgl promoter. In vivo, Mu insertions were focused in two narrow zones of DNA nearbgl, and both zones exhibited a striking orientation bias. Five hot spots upstream of the bgl cyclic AMP binding protein (CAP) binding site had Mu insertions exclusively with the phage oriented left to right relative to the direction of bgl transcription. One hot spot within the CAP binding domain had the opposite (right-to-left) orientation of phage insertion. The DNA segment lying between these two Mu hot-spot clusters is extremely A/T rich (80%) and is an efficient target for insertion sequences during stationary phase. IS1 insertions that activate the bgl operon resulted in a decrease in Mu insertions near the CAP binding site. Mu transposition in vitro differed significantly from the in vivo transposition pattern, having a new hot-spot cluster at the border of the A/T-rich segment. Transposon hot-spot behavior and orientation bias may relate to an asymmetry of transposon DNA-protein complexes and to interactions with proteins that produce transcriptionally silenced chromatin.
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Majorowicz, J., J. Šafanda und K. Osadetz. „Modeling of stability of gas hydrates under permafrost in an environment of surface climatic change – terrestrial case, Beaufort-Mackenzie basin, Canada“. Climate of the Past Discussions 7, Nr. 5 (15.09.2011): 2863–91. http://dx.doi.org/10.5194/cpd-7-2863-2011.

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Abstract. Modeling of the onset of permafrost formation and succeeding gas hydrate formation in the changing surface temperature environment has been done for the Beaufort-Mackenzie Basin (BMB). Numerical 1-D modeling is constrained by deep heat flow from deep well bottom hole temperatures, deep conductivity, present permafrost thickness and thickness of Type I gas hydrates. Latent heat effects were applied to the model for the entire ice bearing permafrost and Type I hydrate intervals. Modeling for a set of surface temperature forcing during the glacial-interglacial history including the last 14 Myr was performed. Two scenarios of gas formation were considered; case 1: formation of gas hydrate from gas entrapped under deep geological seals and case 2: formation of gas hydrate from gas in a free pore space simultaneously with permafrost formation. In case 1, gas hydrates could have formed at a depth of about 0.9 km only some 1 Myr ago. In case 2, the first gas hydrate formed in the depth range of 290–300 m shortly after 6 Myr ago when the GST dropped from −4.5 °C to −5.5. °C. The gas hydrate layer started to expand both downward and upward subsequently. These models show that the gas hydrate zone, while thinning persists under the thick body of BMB permafrost through the current interglacial warming periods.
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Aliyah, Ummu, Mohamad Hariyadi und Prihadi Prihadi. „Development Of Batik Mangrove As A Community Empowerment Effort In The Banyuurip Village Ujung Pangkah Gresik“. Kontribusia (Research Dissemination for Community Development) 3, Nr. 1 (21.01.2020): 272. http://dx.doi.org/10.30587/kontribusia.v3i1.1142.

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Fishing group Tirta Buana, around the beach of Banyuurip village, Ujung-Gresik. Cooperate with FERTILIZER and PT. PGN SAKA is Limited to hold the center of seedlings and mangrove sales. Until then from this mangrove business make a new tourist destination called Banyuurip Mangrove Center (BMC). Mangrove Banyuurip Ujungsemini lately visited by many domestic tourists. It is located about 35 kilometers from the city of Surabaya or about 23 kilometers from the city of Gresik to the north. The average day of visitors who come 600 people, but at the time of the feast can reach 1,600 visitors. The large number of tourists who come to enjoy the beautiful panorama of Mangrove if handled precisely will bring their source of income for the community Banyu Urip, the tip of the step has not been optimally absorbed. Several business opportunities will be directed in this Community Partnership program which includes: the empowerment of mangrove crops such as batik handicrafts made from mangrove, dodol mangrove and syrup made from mangrove. Seafood products are also the potential for the development of the production of the main shells. Besides the improvement of the facilities and Preasarana mangrove forest itself needs to be beautified so that visitors energy comfortable and feel at home in enjoying tourism of the BMC Mangrove such as The Making of jogging track to the shore of white sand, Gazebo level that So that tourists can see mangrove forests from above as well as repair and illumination of the road to access tourist attractions.
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Joyce, Peter, und Wendy Laverick. „Spit guards, ethical policing and the need for an evidence-based approach“. Safer Communities 17, Nr. 3 (09.07.2018): 145–55. http://dx.doi.org/10.1108/sc-04-2018-0013.

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Purpose The purpose of this paper is to assess the advantages and disadvantages of the use of spit guards by police forces in the UK and to make recommendations regarding an evidence-based approach to decisions related to the use of such equipment. Design/methodology/approach The paper is based upon an examination of a range of primary source material, secondary sources and grey literature. Findings Although the use of spit guards can be justified by factors that include the need to protect police officers from contracting serious infectious diseases, there are a number of problems that concern ethical policing and human rights. Concerns arise when spit guards are deployed against vulnerable individuals, are used offensively rather than defensively and when such equipment is deployed disproportionately against persons from Black and Minority Ethnic (BME) communities. Additionally, the image of the police may suffer if spit guards are accompanied by the use of excessive force which may be perceived as an abuse of police power. Practical implications The paper makes recommendations that a comprehensive evidence base is required to assist practitioners to make informed decisions regarding the deployment of spit guards. This evidence base should include the extent to which officers are spat at, medical evidence relating to spitting and the transmission of serious diseases, the views of the public concerning the deployment of spit guards and estimations as to whether such equipment will deter spitting by suspects of crime. Originality/value This paper provides an original academic contribution to the ongoing debate on the use of spit guards within policing. In particular, it brings together a wide range of material that relates to this topic and presents it as a coherent set of arguments located in a single source.
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Jensen, Jonas, Casper Bindzus Foldager, Thomas Vestergaard Jakobsen, Kjeld Søballe, Cody Bünger und Jorgen Baas. „Use of Carboxymethyl Cellulose and Collagen Carrier with Equine Bone Lyophilisate Suggests Late Onset Bone Regenerative Effect in a Humerus Drill Defect – A Pilot Study in Six Sheep“. Open Orthopaedics Journal 4, Nr. 1 (11.05.2010): 181–87. http://dx.doi.org/10.2174/1874325001004010181.

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We assessed the use of a filler compound together with the osteoinductive demineralized bone matrix (DBM), Colloss E. The filler was comprised of carboxymethyl-cellulose and collagen type 1. The purpose of the study was to see if the filler compound would enhance the bone formation and distribute the osteoinductive stimulus throughout the bone defect. Six sheep underwent a bilateral humerus drill defect. The drill hole was filled with a compound consisting of 100 mg CMC, 100 mg collagen powder, and 1 ccm autologous full blood in one side, and a combination of this filler compound and 20 mg Colloss E in the other. The animals were divided into three groups of two animals and observed for 8, 12 and 16 weeks. Drill holes was evaluated using quantitative computed tomography (QCT), micro computed tomography (µCT) and histomorphometry. Mean total bone mineral density (BMD) of each implantation site was calculated with both QCT and µCT. Bone volume to total volume (BV/TV) was analyzed using µCT and histomorphometry. Although not statistically significant, results showed increased bone BMD after 16 weeks in µCT data and an increased BV/TV after 16 weeks in both µCT and histology. Correlation between QCT and µCT was R2 = 0.804. Correlation between histomorphometry and µCT BV/TV data was R2 = 0.8935 and with an average overrepresentation of 8.2% in histomorphometry. In conclusion the CMC-Collagen + Colloss E filler seems like a viable osteogenic bone filler mid- to long term. A correlation was found between the analytical methods used in this study.
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Ghatan, Sam, Fariba Ahmadizar, Ruolin Li, Carolina Medina-Gomez, Maria Carola Zillikens, Fernando Rivadeneira, Maryam Kavousi und Ling Oei. „Type 2 Diabetes Clusters Indicate Diabetes Duration Key in Fracture Risk“. Journal of the Endocrine Society 5, Supplement_1 (01.05.2021): A280—A281. http://dx.doi.org/10.1210/jendso/bvab048.570.

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Abstract Introduction: Individuals with type 2 diabetes mellitus (T2DM) are at an increased risk of developing fractures, despite higher mean BMI and BMD. Recently, clinically-relevant sub-groups of T2DM have been characterised using biomarkers of glycemic metabolism. Aim: Characterise T2DM sub-groups in a population-based setting and test for differences in fracture risk. Methods: A total of 10019 Rotterdam Study participants were available with glycemic and (incident) fracture follow-up. Participants with T2DM (n=1678) were partitioned in subgroups using K-means clustering based on: HOMA-B, HOMA-IR, age of diabetes onset, BMI and waist circumference measurements. Non-vertebral fracture risk was estimated across T2D subgroups using Cox proportional hazard models, adjusted for sex, age, BMI, collection cohort and prevalent T2DM. Results: Four T2D clusters were defined each with relatively-unique clinical characteristics namely, 1) advanced age of onset; 2) decreased insulin sensitivity; 3) beta-cell disfunction; 4) Obesity/high BMI. Individuals with prevalent and incident T2DM (independent of cluster) had lower risk of fracture than non-diabetics (see Forest plot). In contrast, individuals with prevalent T2DM (n=1152) had increased risk of non-vertebral fracture (HR: 2.1, 95%CI: 1.65–2.76), than individuals without T2DM. Conclusion: Despite that partitioning the heterogeneity of T2DM in clinically-meaningful clusters opens the road to tailored prevention and care, our findings with prevalent T2DM indicate that disease duration (likely with inadequate glycemic control) is the main determinant of fracture risk. In line with this contention, the association between T2DM and fracture risk is not causal, as causality requires association with incident cases, as also confirmed by earlier Mendelian randomization studies. Future work, using genetically-determined disease definitions and biomarkers will help unveil clusters of individuals with T2DM at increased risk of fracture.
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Supriatiningsih, Eka. „PERLINDUNGAN HUKUM TERHADAP HAK KONSUMEN DALAM INDUSTRI PERUMAHAN MENURUT UNDANG-UNDANG NOMOR 8 TAHUN 1999 TENTANG PERLINDUNGAN KONSUMEN“. DE RECHTSSTAAT 2, Nr. 2 (25.04.2017): 141–56. http://dx.doi.org/10.30997/jhd.v2i2.665.

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Housing is a basic human need. But for the majority of the Indonesian people, the word "home" became the term that is very expensive, but the house is a building basic, fundamental and also a prerequisite for everyone to survive and live and enjoy life dignified, peaceful, safe and comfortable. Many problems regarding housing draw made this issue to be studied. Identification of research problems are 1) How is the role and perspectives of Law No. 8, 1999 (BFL) for violation of consumer rights in the housing industry?; 2) The extent to which the responsibility of the developer or developer to default or negligence in carrying out obligations, and how the reality faced by consumers?; 3) what legal action can be taken if a dispute arises consumers with businesses?. This study is a descriptive analysis is intended to provide a detailed overview of the rights of consumers in the housing industry, to see the problems that exist in the present and perspective of research that its analysis leads to the future in order to find the right policy to consumer protection housing. From these results it can be concluded that: 1) the implementation of Law No. 8 of 1999 on Consumer Protection (BFL), especially regarding the implementation of consumer rights cannot be realized as a whole, particularly with regard to the behavior for the rights, such as rights advocacy, the right to obtain redress. 2) On the issue of consumer protection, based on the findings directly in the field indicates that Act No. 8, 1999 do not yet play as expected at the time of enactment. 3) Control the government to businesses in the housing industry or developers so far only limited to licensing only, while the interactions or direct relationship between developers and consumers, the government does not intervene. On the advice of the above conclusions are: 1) There needs to be a social movement about empowering consumers so considered important encouragement for socialization activities; 2) Establishment of an independent body specialized dispute resolution field of housing or property in Indonesia is quite urgent, given the weak position of the consumer; 3) For a more integrative and comprehensive reach the target of legal protection to consumers, Act No. 8 of 1999 on Consumer Protection in the implementation must be accompanied by implementing regulations.
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Chiappori, A., M. T. Schreeder, M. M. Moezi, J. Stephenson, J. L. Blakely, R. Salgia, Q. S. Chu, S. M. Malik, M. M. Modiano und M. S. Berger. „A phase Ib trial of Bcl-2 inhibitor obatoclax in combination with carboplatin and etoposide for previously untreated patients with extensive-stage small cell lung cancer (ES-SCLC)“. Journal of Clinical Oncology 27, Nr. 15_suppl (20.05.2009): 3576. http://dx.doi.org/10.1200/jco.2009.27.15_suppl.3576.

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3576 Background: Obatoclax (Ob) is a small-molecule antagonist of all the Bcl-2 prosurvival proteins. In vitro it enhances the effects of the drugs cisplatin and etoposide. Bcl-2 family proteins are frequently expressed in SCLC, and SCLC cell lines are sensitive to Ob. Methods: This study was designed to find the maximal tolerated doses (MTD) of oOb when given on a 21 day (D) cycle together with carboplatin (AUC 5 D1) and etoposide (100 mg/m2 D1–3), in separate dose escalations using Ob as a 3-hr infusion D1–3 and as a 24-hr infusion D1–3. Eligible patients had ES-SCLC, measurable disease, ≤1 prior therapy, ECOG PS ≤1, and adequate hematological, renal and hepatic function. 3- 6 patients were enrolled into ascending dose cohorts with standard DLT rules evaluating safety in C1 to determine dose escalation. Results: 24 patients were enrolled into 5 dosing cohorts (14 males; median age 67). A total of 66 cycles (C) have been administered to date. There were no DLTs in the initial cohorts using Ob 15 mg over 3 hr or Ob 30 mg over 24 hr. Two DLTs occurred in the Ob 30 mg over 3 hr cohort - both due to myelosuppression in previously treated patients. As a result, the trial was amended to exclude previously treated patients. 5 previously untreated patients receiving Ob 30 over 3 hr had no DLTs. There were no DLTs in the Ob 45 mg over 24 hr cohort but 2 patients in the Ob 24-hr infusion cohorts had infusion pump malfunctions while at home. There were 2 DLTs in the Ob 45 mg over 3 hr cohort (somnolence, euphoria, & disorientation) establishing MTD of Ob 30 mg over 3 hr daily x 3. After C2 the 6 previously untreated patients on Ob 24-hr infusion cohorts had 3 PRs, 1 SD, 1 PD, and 1 Unk; the 2 previously treated patients had PRs. After C2 all 7 previously-untreated patients at 15 or 30 mg in the 3-hr infusion cohorts have PR; the 3 previously treated patients had SD. Conclusions: Ob can be combined with carboplatin and etoposide using either a 3-hr or a 24-hr infusion, and both regimens are associated with high early response rates in ES-SCLC, perhaps due to inhibition of mcl-1. Due to practical issues with the 24-hr infusion arm, the 3-hr 30 mg MTD dose will be utilized in a randomized phase II versus carboplatin and etoposide alone. [Table: see text]
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Dissertationen zum Thema "BML Home Set"

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Slámová, Hana. „Forenzní analýza prostředí IoT ze stop síťové komunikace“. Master's thesis, Vysoké učení technické v Brně. Fakulta informačních technologií, 2021. http://www.nusl.cz/ntk/nusl-445577.

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The goal of this master's thesis is a creation of dataset capturing selected users' activities, network analysis of this dataset, design and implementation of method to detect selected users' activities and discussion of achieved results. 4 devices have been chosen for the creation of this dataset.
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Buchteile zum Thema "BML Home Set"

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Pachauri, Saroj, Ash Pachauri und Komal Mittal. „Female Sex Work Dynamics: Empowerment, Mobilization, Mobility“. In SpringerBriefs in Public Health, 43–60. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-16-4578-5_4.

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AbstractUNAIDS defines sex work as selling sexual services (Ditmore in Joint United Nations Programme on HIV/AIDS. UNAIDS, 2008, [1]). Sex workers involved in sexual relations with multiple partners are a key group of women who need access to comprehensive sexual health services, including HIV prevention, treatment, and care (Lafort et al. in Reproductive health services for populations at high risk of HIV: performance of a night clinic in Tete province, Mozambique. BMC Health Services Research, 2010, [2]). There are a broad range of sex workers in various locations including those who are street-based and brothel-based, those who work as escorts, and those who work from their own homes.
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Jonker, Jan, und Niels Faber. „External Test“. In Organizing for Sustainability, 125–35. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-78157-6_10.

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AbstractThe external test is the tenth and final building block of the first and second stage of the Business Model Template (BMT). You will test the viability of the business model concept you have developed so far. You can test your business model idea against all kinds of criteria. If you do not have much time, perform your check on the basis of the very concise set of seven questions we provide. But we also provide many other tools in this chapter. Please bear in mind that you must be well-prepared when looking for feedback. Look for people you know or hope will respond critically and constructively. Going through the External Test steps may mean that you need to partially adjust some elements of your business model before you move on. So be it. Remember that every version of your business model in this stage is a beta version and that feedback will help to make it better.
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Jonker, Jan, und Niels Faber. „The Art of Doing“. In Organizing for Sustainability, 177–86. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-78157-6_14.

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AbstractThe purpose of the Business Model Template (BMT) is to help you turn your idea into a viable project or organization. To illustrate this, two real-life case studies are offered in this chapter. Firstly, the KipCaravan project, which is a mobile home—a caravan—for chickens. It involves low-scale egg production in several locations. Secondly, the Sun at School NSV2 project in the city of Nijmegen. For both projects you will find a step-by-step description of the different routes followed. As you will see, the interpretation of the building blocks is different for every project and there is no best order in which to stack the building blocks. Bear in mind that both projects are still up and running successfully at the time of writing. These examples are shown in simplified versions and with the benefit of hindsight, of course. Perhaps the essence of doing business is having the courage to start without a ready-made recipe.
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Konferenzberichte zum Thema "BML Home Set"

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Biondi, B. „Cost Effective Permanent Well Plug & Abandon on Cluster-X With Complex Well Conditions“. In Digital Technical Conference. Indonesian Petroleum Association, 2020. http://dx.doi.org/10.29118/ipa20-se-108.

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Regulation PTK-040 SKK MIGAS explained that the oil company must permanently close the wells post-production operations. Cluster-X has complex well conditions, so the observation needs to be cost-effective. The observation on this case refers to SNI 13-6910-2002 explaining the permanent abandonment of wells in the isolation of open-hole zones, perforation zones, blockage of casing stub (junk) as Primary well-barrier and the annular space blockage as a Secondary well-barrier. The next stage is the surface plug as an environmental isolation plug. API BUL E3-FIRST EDITION & NORSOK STANDARD D-010 are also needed for permanent abandonment on surface capping and slotted-liners in multiple reservoirs. Additional references such as API-Spec-10A are needed. The final stage is the testing of cement plugs, hole cleaning process, and budgeting. This paper discusses various conditions of wells on Cluster-X such as abnormally high pressure, cement plug with open-hole slotted-liners in multiple reservoirs, and junk left in-hole. The first step was to run with a balance plug method on ± 10,500-10,971 ft MD as Primary well-barrier. The next step was to run a cement squeeze method with bridge plug on ±7200-7500 ft MD as Secondary well-barrier. On the step of environmental isolation plug a cement plug retainer was run as a weight test with 15,000 pounds the same on previous steps. Type G class cement was selected to cement plug and ran off section milling tools above of the overpressure zone. The wells closure method compares between rigless method coiled tubing unit and portable rig (conventional) which can optimize plug & abandonment operating time and operational cost.
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Crhová, Marie, Iva Hrnčiříková, Radka Střeštíková, Klára Šoltés-Mertová, Martin Komzák, Kateřina Kapounková und Anna Ondračková. „Effect of a 3-month Exercise Intervention on Physical Performance, Body Composition, Depression and Autonomic Nervous System in Breast Cancer Survivors: A Pilot Study“. In 12th International Conference on Kinanthropology. Brno: Masaryk University Press, 2020. http://dx.doi.org/10.5817/cz.muni.p210-9631-2020-50.

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Purpose: Breast cancer patients are at increased risk of developing comorbidities such as lymphedema, sarcopenia, osteoporosis and cardiovascular disease after breast cancer treatment. These complications contribute to a decrease in quality of life, cardiorespiratory fitness and muscle strength. Regular and long-term physical activity is an effective non-pharmacological strategy that can improve physical, psychological and social outcomes. The aim of our research was to evaluate the effect of various modes of an exercise intervention on physical performance, body composition, depression and autonomic nervous system in breast cancer survivors. Methods: 16 women after surgery with hormonal treatment enter the research. Thirteen of them completed the controlled, quasi-experimental study (54 ± 9 yrs, 164cm ± 6cm, 72 ± 12kg) and were divided into 3 groups according to their place of living: trained under supervision (n=5) (SUPERV), trained at home without supervision by videos (n=7) (HOME) and with no prescribed physical activity (n=4) (CON). Exercise intervention lasted 3 months and comprised of 60 min training units 3 × week (aerobic with resistant exercise in a 2 : 1 mode combined with regular weekly yoga and breathing exercises). The exercise intensity was set individually at 65–75% of HRR based on spiroergometry and was continuously controlled by heart rate monitors. The same principles applied to the HOME group, which, in addition to heart rate monitors, recorded frequency, length, HRmax, HRavg, and Borg scale of intensity perception. VO2max, BMI, fat mass, depression level (Beck’s depression inventory) and the power of the autonomic nervous system (total power and sympatho-vagal balance) were analyzed. For data evaluation we used descriptive statistics and Cohens d effect size. Results: 3 women dropped out of research because of medical reason. In all groups VO2max values increased. The largest increase in VO2max values was in SUPERV group by 36%, in HOME group by 20% and in CON group by 2%. Body weight decreased for groups SUPERV (˗1.2 kg) and CON (-0.1kg), for HOME group there was an increase (+0.2 kg). Body mass index decreased for SUPERV group (-0.4), for HOME and CON it increased (both +0.1). Total power decreased in SUPERV (-0.6) and HOME group (-0.2), in CON has not changed. The same results were achieved by the sympatho-vagal balance, only the CON group increased. Values from Beck’s depression inventory decreased for all groups, most for CON group. Conclusion: A 3-months of supervised and controlled exercise had a significant effect on physical fitness and body composition in comparison with non-supervised home-based physical intervention. Our results indicate that it is strongly advisable to apply a supervised exercise program to induce positive physiological changes in breast cancer survivors as part of aftercare.
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Barreiro, Jose A., John S. Knowles, Carl R. Johnson, Iain D. Gordon und Lene K. Gjerde. „Successful Application of a Reinforced Composite Mat Pill Technology for Lost Circulation Control in the Norwegian Continental Shelf“. In SPE/IADC International Drilling Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/204062-ms.

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Abstract An operator in the Norwegian continental shelf (NCS) required sufficient zonal isolation around a casing shoe to accommodate subsequent targeted injection operations. Located in the Ivar Aasen field, and classified as critical, the well had a 9 ⅝-in. casing shoe set in the depleted Skagerrak 2 reservoir. The lost circulation risk was high during cementing because the Hugin formation, located above the reservoir, contained 40 m [~ 131.2 ft] of highly porous and permeable sandstone. During previous operations in the field, lost circulation was observed before and during the casing running and cementing operations. After unsuccessful attempts to cure the losses with various lost circulation materials, a new solution was proposed to target the specific lost circulation problem by combining two types of reinforced composite mat pill (RCMP) technology. Specifically, the first type of RCMP technology was engineered for use in the viscous preflush spacer, and the second was applied to the cement slurry itself. Working in synergy, the RCMP systems mitigated the risk of incomplete zonal isolation. With no losses observed upon reaching total depth (TD) for the 12 ¼-in. hole, the 9 ⅝-in. casing was run with a reamer shoe and 15 rigid centralizers. Between 2700 and 2728 m [~ 8,858 and 8,950 ft] measured depth (MD), the rig observed constant drag of 30 to 40 MT whilst working the casing down, and circulation was completely lost before partial returns were eventually observed. The rig continued to work the string down to the planned landing depth at 3897 m [~ 12,785 ft] MD. Precementing circulation ensued with staged pump rates increasing at 100-L/min [~ 0.6-bbl/min] intervals up to 1400 L/min [~ 8.8 bbl/min], which induced losses at a rate of 6.5 m3/hour [~ 40 bbl/hour]). Subsequently, the flow rate was reduced to 1300 L/min [~ 8.1 bbl/min], and the annular volume was circulated 2.6 times with full returns. Attempts to reduce equivalent circulating density (ECD) ahead of the cementing operation were implemented at 1300 L/min [~ 8.1 bbl/min] using a low-density, low-rheology oil-based drilling fluid pill. However, a significant loss rate of 18.0 m3/hour [~113 bbl/hour] was observed. The flow rate was reduced to 950 L/min [~ 6.0 bbl/min], and partial circulation was recovered. After the spacer and cement had reached the annulus, full returns were immediately observed and continued until the top plug was successfully bumped. Acoustic logging determined that the operation had achieved the primary job objective of establishing the required length of hydraulically isolating cement in the annulus. Lost circulation is a costly problem that can be difficult to solve, even with the wide variety of technologies available (Vidick, B., Yearwood, J. A., and Perthuis, H. 1988. How To Solve Lost Circulation Problems. SPE-17811-MS). This case study demonstrates a successful solution. The operator will be able to incorporate lessons learned and best practices into future operations, and these lessons and practices will be useful to other operators with similar circumstances.
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Matusik, Katarzyna E., Daniel J. Duke, Nicholas Sovis, Andrew B. Swantek, Christopher F. Powell, Raul Payri, Daniel Vaquerizo, Sebastian Giraldo-Valderrama und Alan L. Kastengren. „A study on the relationship between internal nozzle geometry and injected mass distribution of eight ECN Spray G nozzles.“ In ILASS2017 - 28th European Conference on Liquid Atomization and Spray Systems. Valencia: Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/ilass2017.2017.4766.

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Gasoline direct injection (GDI) nozzles are manufactured to meet geometric specifications with length scales onthe order of a few hundred microns. The machining tolerances of these nominal dimensions are not always knowndue to the difficulty in accurately measuring such small length scales in a nonintrusive fashion. To gain insight intothe variability of the machined dimensions as well as any effects that this variability may have on the fuel spraybehavior, a series of measurements of the internal geometry and fuel mass distribution were performed on a set ofeight nominally duplicate GDI “Spray G” nozzles provided by the Engine Combustion Network. The key dimensionsof each of the eight nozzle holes were measured with micron resolution using full spectrum x-ray tomographicimaging at the 7-BM beamline of the Advanced Photon Source at Argonne National Laboratory. Fuel densitydistributions at 2 mm downstream of the nozzle tips were obtained by performing x-ray radiography measurementsfor many lines of sight. The density measurements reveal nozzle-to-nozzle as well as hole-to-hole density variations.The combination of high-resolution geometry and fuel distribution datasets allows spray phenomena to be linked tospecific geometric characteristics of the nozzle, such as variability in the hole lengths and counterbore diameters,and the hole inlet corner radii. This analysis provides important insight into which geometrical characteristics ofthe nozzles may have the greatest importance in the development of the injected sprays, and to what degreethese geometric variations might account for the total spray variability. The goal of this work is then to further theunderstanding of the relationship between internal nozzle geometry and fuel injection, provide input to improvecomputational models, and ultimately aid in optimizing injector design for higher fuel efficiency and lower emissionsengines.DOI: http://dx.doi.org/10.4995/ILASS2017.2017.4766
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Kim, Tae-Hoon, Oe-Ju Hwang und Yeong-Tae Oh. „Comparative Study on Fatigue Life of Drillship Operating for GoM and Brazil Sectors Based on Spectral Fatigue Analysis“. In ASME 2013 32nd International Conference on Ocean, Offshore and Arctic Engineering. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/omae2013-10593.

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A drillship is an exceptional vessel to be capable of drilling of new oil or gas wells, and carrying out maintenance or completion work in deep water. The drillship also has ability to take aboard much more variable loads and save the time of sailing between oil fields worldwide than Semi-submersible rig. Sometimes, it is required from design specifications that a drillship is to be designed to be satisfactory to several fields at the same time to maximize such advantages. This paper describes results of the comparative study on fatigue life of a drillship, which was developed by DSME, operating for both GoM (Gulf of Mexico) and Brazil sectors. It was assumed in the calculation that the drillship spends 80% of her life in On-site (GoM and/or Brazil sector) and other percentage in transit condition. Screening works for choosing fatigue sensitive locations such as moon pool corners, discontinuous areas, topside module foundations, etc., were performed referring to the local strength analysis. A whole ship model along with every topside module was generated and the very fine meshes with thickness by thickness as per DNV RP-C203 were embedded therein. Stress RAOs of critical hotspot locations of the drillship were directly obtained through its motions from 3D potential-theory-based analysis, i.e. DNV WADAM. In the analysis, wave scatter diagrams given by BMT were used. As results of the study, it was found that Brazil sector gives comparatively worse results to the drillship in terms of fatigue endurance and finally, Brazil sector was decided in calculating fatigue lives of the drillship as a representative sea state. The fatigue life was computated based on spectral fatigue analysis by means of DSME’s in-hose tool (i.e. D-SFAS, DSME Spectral Fatigue Analysis System).
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Griffin, J., D. J. Rojas, A. Al Shmakhy und P. Scranton. „Application of Interventionless Single Point Entry Technology to Improve Proppant Placement Control and Well Production“. In SPE Annual Technical Conference and Exhibition. SPE, 2021. http://dx.doi.org/10.2118/205865-ms.

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Abstract The hydraulic fracture treatment (HFT) and its effectiveness to enhance wellbore drainage directly correlate with each well’s overall production performance and underlining economics. This paper will discuss the potential of ultra high stage count Single Point Entry (SPE) sleeves and their ability to increase control over proppant placement and isolation during the HFT as a method for optimizing well performance, economics, and reduce non-uniformity between treatments and wells. To address the limitations of current completion methods, full ID single point entry systems have been developed for open hole and cemented applications. These systems provide unlimited frac stage count with lower frac tortuosity, provide increased control over proppant placement and well production, reduce or eliminate over- flush and formation damage, and achieve higher efficiency during and after frac stimulation than previous conventional plug-and-perf (PnP) and sleeve systems, thereby reducing costs. While the ball-and-seat completion technique revolutionized the efficiency of multi-stage single point entry fracturing, its vast array of limitations (primarily ID restrictions), limited stage count, and compatibility with cemented liners quickly sidelined it in place of PnP. PnP offers increased surface area contact through additional entry points compared to sleeve systems of the past and remains the accepted method for achieving zonal isolation and initiation during stimulation. However, the time intensive operations of PnP present challenges in maintaining efficiencies due to variability in wireline during deployment and coiled tubing during millouts. The increase in number of clusters per stage and number of stages per well achieved with PnP often results in higher stimulated rock volumes (SRV) however, due to the number of multiple clusters open simultaneously, this method gained a "pump-n-pray" reputation due to the uncertainty of cluster efficiency and its unpredictability. The lack of cluster control over the years has created a series of challenges in terms of parent-child well relationships and spacing, economical asset development, and loss of potential production. With over 4,000 stages fracture stimulated across US, Canada, and Asia, some wells containing 220 individual stages, this paper will address the differences in production in terms of bbl of oil equivalent (BOE) for direct and indirect offsets in trials, compare capital efficiency with spud to put on production (POP) timelines, demonstrate economical completion optimization for lower commodity pricing of oil, and carbon intensity reduction measures to lower greenhouse gas emissions.
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Ettema, Roelof, Goran Gumze, Katja Heikkinen und Kirsty Marshall. „European Integrated Care Horizon 2020: increase societal participation; reduce care demands and costs“. In CARPE Conference 2019: Horizon Europe and beyond. Valencia: Universitat Politècnica València, 2019. http://dx.doi.org/10.4995/carpe2019.2019.10175.

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BackgroundCare recipients in care and welfare are increasingly presenting themselves with complex needs (Huber et al., 2016). An answer to this is the integrated organization of care and welfare in a way that personalized care is the measure (Topol, 2016). The reality, however, is that care and welfare are still mainly offered in a standardized, specialized and fragmented way. This imbalance between the need for care and the supply of care not only leads to under-treatment and over-treatment and thus to less (experienced) quality, but also entails the risk of mis-treatment, which means that patient safety is at stake (Berwick, 2005). It also leads to a reduction in the functioning of citizens and unnecessary healthcare cost (Olsson et al, 2009).Integrated CareIntegrated care is the by fellow human beings experienced smooth process of effective help, care and service provided by various disciplines in the zero line, the first line, the second line and the third line in healthcare and welfare, as close as possible (Ettema et al, 2018; Goodwin et al, 2015). Integrated care starts with an extensive assessment with the care recipient. Then the required care and services in the zero line, the first line, the second line and / or the third line are coordinated between different care providers. The care is then delivered to the person (fellow human) at home or as close as possible (Bruce and Parry, 2015; Evers and Paulus, 2015; Lewis, 2015; Spicer, 2015; Cringles, 2002).AimSupport societal participation, quality of live and reduce care demand and costs in people with complex care demands, through integration of healthcare and welfare servicesMethods (overview)1. Create best healthcare and welfare practices in Slovenia, Poland, Austria, Norway, UK, Finland, The Netherlands: three integrated best care practices per involved country 2. Get insight in working mechanisms of favourable outcomes (by studying the contexts, mechanisms and outcomes) to enable personalised integrated care for meeting the complex care demand of people focussed on societal participation in all integrated care best practices.3. Disclose program design features and requirements regarding finance, governance, accountability and management for European policymakers, national policy makers, regional policymakers, national umbrella organisations for healthcare and welfare, funding organisations, and managers of healthcare and welfare organisations.4. Identify needs of healthcare and welfare deliverers for creating and supporting dynamic partnerships for integrating these care services for meeting complex care demands in a personalised way for the client.5. Studying desired behaviours of healthcare and welfare professionals, managers of healthcare and welfare organisations, members of involved funding organisations and national umbrella organisations for healthcare and welfare, regional policymakers, national policy makers and European policymakersInvolved partiesAlma Mater Europaea Maribor Slovenia, Jagiellonian University Krakow Poland, University Graz Austria, Kristiania University Oslo Norway, Salford University Manchester UK, University of Applied Sciences Turku Finland, University of Applied Sciences Utrecht The Netherlands (secretary), Rotterdam Stroke Service The Netherlands, Vilans National Centre of Expertise for Long-term Care The Netherlands, NIVEL Netherlands Institute for Health Services Research, International Foundation of Integrated Care IFIC.References1. Berwick DM. The John Eisenberg Lecture: Health Services Research as a Citizen in Improvement. Health Serv Res. 2005 Apr; 40(2): 317–336.2. Bruce D, Parry B. Integrated care: a Scottish perspective. London J Prim Care (Abingdon). 2015; 7(3): 44–48.3. Cringles MC. Developing an integrated care pathway to manage cancer pain across primary, secondary and tertiary care. International Journal of Palliative Nursing. 2002 May 8;247279.4. Ettema RGA, Eastwood JG, Schrijvers G. Towards Evidence Based Integrated Care. International journal of integrated care 2018;18(s2):293. DOI: 10.5334/ijic.s22935. Evers SM, Paulus AT. Health economics and integrated care: a growing and challenging relationship. Int J Integr Care. 2015 Jun 17;15:e024.6. Goodwin N, Dixon A, Anderson G, Wodchis W. Providing integrated care for older people with complex needs: lessons from seven international case studies. King’s Fund London; 2014.7. Huber M, van Vliet M, Giezenberg M, Winkens B, Heerkens Y, Dagnelie PC, Knottnerus JA. Towards a 'patient-centred' operationalisation of the new dynamic concept of health: a mixed methods study. BMJ Open. 2016 Jan 12;6(1):e010091. doi: 10.1136/bmjopen-2015-0100918. Lewis M. Integrated care in Wales: a summary position. London J Prim Care (Abingdon). 2015; 7(3): 49–54.9. Olsson EL, Hansson E, Ekman I, Karlsson J. A cost-effectiveness study of a patient-centred integrated care pathway. 2009 65;1626–1635.10. Spicer J. Integrated care in the UK: variations on a theme? London J Prim Care (Abingdon). 2015; 7(3): 41–43.11. Topol E. (2016) The Patient Will See You Now. The Future of Medicine Is in Your Hands. New York: Basic Books.
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