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1

DELLA-PORTA, AJ. „The role of the Australian Animal Health Laboratory“. Australian Veterinary Journal 66, Nr. 12 (Dezember 1989): 455–59. http://dx.doi.org/10.1111/j.1751-0813.1989.tb13576.x.

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Lowenthal, John. „Overview of the CSIRO Australian Animal Health Laboratory“. Journal of Infection and Public Health 9, Nr. 3 (Mai 2016): 236–39. http://dx.doi.org/10.1016/j.jiph.2016.04.007.

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3

Selleck, Paul. „A brief history of AAHL“. Microbiology Australia 41, Nr. 4 (2020): 210. http://dx.doi.org/10.1071/ma20056.

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The CSIRO Australian Animal Health Laboratory (AAHL) was officially opened on 1 April 1985. After that day the laboratory switched to secure mode and has operated as such ever since. AAHL was constructed to be the primary national diagnostic facility for exotic animal diseases but has expanded its role to become a national and international reference laboratory for many diseases. AAHL has supported disease control within the region by providing training, reagents and proficiency testing, both within Australia and internationally. AAHL’s role has evolved even further to include a focus on one-health which resulted in AAHL being renamed the Australian Centre for Disease Preparedness (ACDP) in March 2020.
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Wright, Lynda. „Biobanks – serum and cells – human and animals“. Microbiology Australia 40, Nr. 3 (2019): 138. http://dx.doi.org/10.1071/ma19037.

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The Australian Animal Health Laboratory (AAHL), CSIRO is a high-containment facility and a vital part of Australia's national biosecurity infrastructure. AAHL closely collaborates with veterinary and human health agencies globally, as approximately 70 per cent of emerging infectious diseases in people originate in animals. The facility is designed to allow scientific research into the most dangerous infectious agents in the world and contains a large collection of serum and cell lines.
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Scott, Pam. „THE SOCIAL SHAPING OF A LABORATORY: THE ESTABLISHMENT OF THE AUSTRALIAN ANIMAL HEALTH LABORATORY“. Prometheus 6, Nr. 2 (Dezember 1988): 249–62. http://dx.doi.org/10.1080/08109028808629314.

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Scott, Pam. „Culling technological white elephants: Lessons from the Australian Animal Health Laboratory“. Science and Public Policy 16, Nr. 1 (Februar 1989): 47–51. http://dx.doi.org/10.1093/spp/16.1.47.

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FORMAN, AJ. „Recent developments in diagnosis of exotic disease at the Australian Animal Health Laboratory“. Australian Veterinary Journal 70, Nr. 5 (Mai 1993): 161–63. http://dx.doi.org/10.1111/j.1751-0813.1993.tb06118.x.

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RICHARDS, RB, TM ELLIS und JG ALLEN. „Government Animal Health Laboratory Services in Western Australia“. Australian Veterinary Journal 70, Nr. 9 (September 1993): 321–23. http://dx.doi.org/10.1111/j.1751-0813.1993.tb00870.x.

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9

Doyle, Kevin. „Consultation, Conflict, Cooperation and Controversy: a history of the establishment of CSIRO's Australian Animal Health Laboratory - by Snowdon B“. Australian Veterinary Journal 86, Nr. 1-2 (Januar 2008): 42. http://dx.doi.org/10.1111/j.1751-0813.2007.00240.x.

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10

Zemanova, Miriam A. „Crucial but Neglected: Limited Availability of Animal Welfare Courses in Education of Wildlife Researchers“. Animals 13, Nr. 18 (13.09.2023): 2907. http://dx.doi.org/10.3390/ani13182907.

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Animal welfare is a subject of increasing scientific and ethical concern in today’s society, crucial for the well-being of animals used in research and the integrity of scientific data. Equipping researchers in the life science disciplines with a science-based knowledge of animal welfare, behaviour, physiology, and health is, therefore, essential. Nevertheless, previous studies evaluating animal welfare education focused on veterinary, laboratory, or farm animal science. Consequently, the aim of this study was, for the very first time, to map the prevalence of animal welfare courses in the university education of ecologists, wildlife biologists, and conservation managers in Europe, Canada, the USA, Australia, and New Zealand. A comprehensive assessment of 1548 universities was conducted, resulting in the identification of 596 relevant programs at the bachelor’s and master’s levels. Analysis of the curricula revealed that only 1% of the programs offered a formal course on animal welfare, while 65% provided courses on animal behaviour, 59% on animal physiology, and 34% on animal health. However, the majority of these courses were listed as electives rather than mandatory components of the programs. These results underscore the need for universities to incorporate more formal and obligatory education in animal welfare in order to better prepare future ecologists, wildlife biologists, and conservation managers for the challenges of working with wildlife.
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Hemarajata, Peera, Jonathan D. Baghdadi, Risa Hoffman und Romney M. Humphries. „Burkholderia pseudomallei: Challenges for the Clinical Microbiology Laboratory“. Journal of Clinical Microbiology 54, Nr. 12 (21.09.2016): 2866–73. http://dx.doi.org/10.1128/jcm.01636-16.

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Melioidosis is a potentially fatal infection caused by the bacterium Burkholderia pseudomallei . Clinical diagnosis of melioidosis can be challenging since there is no pathognomonic clinical syndrome, and the organism is often misidentified by methods used routinely in clinical laboratories. Although the disease is more prevalent in Thailand and northern Australia, sporadic cases may be encountered in areas where it is not endemic, including the United States. Since the organism is considered a tier 1 select agent according to the Centers for Disease Control and Prevention and the U.S. Department of Agriculture Animal and Plant Health Inspection Service, clinical laboratories must be proficient at rapidly recognizing isolates suspicious for B. pseudomallei , be able to safely perform necessary rule-out tests, and to refer suspect isolates to Laboratory Response Network reference laboratories. In this minireview, we report a case of melioidosis encountered at our institution and discuss the laboratory challenges encountered when dealing with clinical isolates suspicious for B. pseudomallei or clinical specimens from suspected melioidosis cases.
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Trevino, Sylvia R., Jennifer L. Dankmeyer, David P. Fetterer, Christopher P. Klimko, Jo Lynne W. Raymond, Alicia M. Moreau, Carl Soffler et al. „Comparative virulence of three different strains of Burkholderia pseudomallei in an aerosol non-human primate model“. PLOS Neglected Tropical Diseases 15, Nr. 2 (11.02.2021): e0009125. http://dx.doi.org/10.1371/journal.pntd.0009125.

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Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is a major cause of sepsis and mortality in endemic regions of Southeast Asia and Northern Australia. B. pseudomallei is a potential bioterrorism agent due to its high infectivity, especially via inhalation, and its inherent resistance to antimicrobials. There is currently no vaccine for melioidosis and antibiotic treatment can fail due to innate drug resistance, delayed diagnosis and treatment, or insufficient duration of treatment. A well-characterized animal model that mimics human melioidosis is needed for the development of new medical countermeasures. This study first characterized the disease progression of melioidosis in the African green monkey (AGM) and rhesus macaque (RM) for non-human primate model down-selection. All AGMs developed acute lethal disease similar to that described in human acute infection following exposure to aerosolized B. pseudomallei strain HBPUB10134a. Only 20% of RMs succumbed to acute disease. Disease progression, immune response and pathology of two other strains of B. pseudomallei, K96243 and MSHR5855, were also compared using AGMs. These three B. pseudomallei strains represent a highly virulent strain from Thailand (HBPUB101034a), a highly virulent strains from Australia (MSHR5855), and a commonly used laboratory strains originating from Thailand (K96243). Animals were observed for clinical signs of infection and blood samples were analyzed for cytokine responses, blood chemistry and leukocyte changes in order to characterize bacterial infection. AGMs experienced fever after exposure to aerosolized B. pseudomallei at the onset of acute disease. Inflammation, abscesses and/or pyogranulomas were observed in lung with all three strains of B. pseudomallei. Inflammation, abscesses and/or pyogranulomas were observed in lymph nodes, spleen, liver and/or kidney with B. pseudomallei, HBPUB10134a and K96243. Additionally, the Australian strain MSHR5855 induced brain lesions in one AGM similar to clinical cases of melioidosis seen in Australia. Elevated serum levels of IL-1β, IL-1 receptor antagonist, IL-6, MCP-1, G-CSF, HGF, IFNγ, MIG, I-TAC, and MIP-1β at terminal end points can be significantly correlated with non-survivors with B. pseudomallei infection in AGM. The AGM model represents an acute model of B. pseudomallei infection for all three strains from two geographical locations and will be useful for efficacy testing of vaccines and therapeutics against melioidosis. In summary, a dysregulated immune response leading to excessive persistent inflammation and inflammatory cell death is the key driver of acute melioidosis. Early intervention in these pathways will be necessary to counter B. pseudomallei and mitigate the pathological consequences of melioidosis.
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Yusuf, P. O., S. Dahiru, M. P. Ameh, J. S. Oyetunde, G. Ada, E. S. Idoga, I. O. Akefe, C. U. Attah und E. Ajagun. „Embryonated eggs as an alternative to animals in the determination of median lethal dose (LD50) in bitis venom“. Sokoto Journal of Veterinary Sciences 21, Nr. 1 (13.06.2023): 43–46. http://dx.doi.org/10.4314/sokjvs.v21i1.5.

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Determination of median lethal dose (LD50) is a vital tool adopted by the World Health Organization for pre-clinical assessment of products for use in the management of snakebite envenoming, a condition which is now included among the list of Neglected Tropical Diseases in 2017. The current trend in the determination of LD50 involves the use of laboratory animals, tens or even hundreds of animals are sacrificed to achieve this goal. This study aimed to find reliable alternatives to this sacrificing of laboratory animals for research purposes. This study investigated the comparative similarities or differences in results obtained from the use of laboratory animals and embryonated eggs in the determination of LD50 in snake venom research. The median lethal dose (LD50) was determined using female mice using the up and down method and Probit method as well as embryonated eggs. There was no statistical difference in the LD50 of the venom of Bitis arietans obtained by the up and down method and that of the conventional probit analysis (p≤0.05) (0.325 mg/kg [probit] and 0.351 mg/kg [up and down] respectively). There was also no statistical difference in the LD50 of the venom of Bitis arietans by the up and down method, conventional probit method, and by the use of embryonated eggs (p≤0.05) (0.325 mg/kg [probit], 0.351 mg/kg [up and down], and 0.392 mg/kg [embryonated eggs). The three methods used produced values of LD50 that were within the range reported on the Australian snake and venom database of 2007. The results suggest embryonated eggs can conveniently replace the use of laboratory animals in the determination of LD50 in snake venom research to ease the ethical challenges posed by excessive use of laboratory animals in snake venom research.
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Lambert, T. W., C. F. B. Holmes und S. E. Hrudey. „Microcystin class of toxins: health effects and safety of drinking water supplies“. Environmental Reviews 2, Nr. 2 (01.07.1994): 167–86. http://dx.doi.org/10.1139/a94-011.

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The microcystins are produced by several species of common planktonic cyanobacteria found in surface waters, but their biological function remains unknown. The microcystins have been shown to be extremely potent hepatotoxins in a variety of experimental animals and they are lethal at low doses. Microcystin-LR, one of over 40 microcystin analogues, has also been shown to be a potent tumor promoter. The toxic effects of the microcystins have been attributed to the inhibition of protein phosphatases. This inhibition causes collapse of the cytoskeleton and interferes with a general signal transduction mechanism in cells. The presence of toxic cyanobacteria in surface water has been documented in all parts of the world. The microcystins have been related to a few incidents of human illness and several incidents of animal poisoning in Canada, United States, Australia, Europe, and Africa. Therefore, exposure to the microcystins is a potentially significant health risk and toxin removal from drinking water is becoming a concern worldwide. Conventional water treatment processes (coagulation/sedimentation, chlorination) have generally proven ineffective at removing microcystin toxins from drinking water. Activated carbon, ozone, and free chlorine have been effective in removing microcystins below detectable concentrations in laboratory experiments. Considering these factors, the occurrence of microcystins in drinking water supplies deserves serious attention to insure that adverse health effects are prevented.Key words: microcystins, hepatotoxins, cyanobacteria, blue-green algae, water treatment, health risk.
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Mayne, Darren J., Kelly-Anne Ressler, Diane Smith, Gareth Hockey, Susan J. Botham und Mark J. Ferson. „A Community Outbreak of Cryptosporidiosis in Sydney Associated with a Public Swimming Facility: A Case-Control Study“. Interdisciplinary Perspectives on Infectious Diseases 2011 (2011): 1–6. http://dx.doi.org/10.1155/2011/341065.

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In February, 2008, the South Eastern Sydney Illawarra Public Health Unit investigated an outbreak of cryptosporidiosis within the south east region of Sydney, Australia. Thirty-one cases with laboratory-confirmed cryptosporidiosis and 97 age- and geographically matched controls selected by random digit dialling were recruited into a case-control study and interviewed for infection risk factors. Cryptosporidiosis was associated with swimming at Facility A (matched odds ratio = 19.4, 95% confidence interval: 3.7–100.8) and exposure to household contacts with diarrhoea (matched odds ratio = 7.7, 95% confidence interval: 1.9–31.4) in multivariable conditional logistic regression models. A protective effect for any animal contact was also found (matched odds ratio = 0.2, 95% confidence interval: 0.1–0.7).Cryptosporidium hominissubtype IbA10G2 was identified in 8 of 11 diagnostic stool samples available for cases. This investigation reaffirms the importance of public swimming pools as potential sources ofCryptosporidiuminfection and ensuring their compliance with water-quality guidelines. The protective effect of animal contact may be suggestive of past exposure leading to immunity.
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SMITH, C. S., A. McLAUGHLIN, H. E. FIELD, D. EDSON, D. MAYER, S. OSSEDRYVER, J. BARRETT und D. WALTISBUHL. „Twenty years of Hendra virus: laboratory submission trends and risk factors for infection in horses“. Epidemiology and Infection 144, Nr. 15 (30.06.2016): 3176–83. http://dx.doi.org/10.1017/s0950268816001400.

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SUMMARYHendra virus (HeV) was first described in 1994 in an outbreak of acute and highly lethal disease in horses and humans in Australia. Equine cases continue to be diagnosed periodically, yet the predisposing factors for infection remain unclear. We undertook an analysis of equine submissions tested for HeV by the Queensland government veterinary reference laboratory over a 20-year period to identify and investigate any patterns. We found a marked increase in testing from July 2008, primarily reflecting a broadening of the HeV clinical case definition. Peaks in submissions for testing, and visitations to the Government HeV website, were associated with reported equine incidents. Significantly differing between-year HeV detection rates in north and south Queensland suggest a fundamental difference in risk exposure between the two regions. The statistical association between HeV detection and stockhorse type may suggest that husbandry is a more important risk determinant than breedper se. The detection of HeV in horses with neither neurological nor respiratory signs poses a risk management challenge for attending veterinarians and laboratory staff, reinforcing animal health authority recommendations that appropriate risk management strategies be employed for all sick horses, and by anyone handling sick horses or associated biological samples.
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Turnidge, J. „Antimicrobial stewardship: what is it, and how does it work?“ Animal Production Science 55, Nr. 12 (2015): 1432. http://dx.doi.org/10.1071/an15272.

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Antimicrobial stewardship is emerging as a vital management tool in the efforts to contain antimicrobial resistance and retain the efficacy of available agents. It is based on a set of concepts about antimicrobial use and resistance that have been developed over the past 70 years. There are seven basic requirements for a stewardship program to function at a local level, including (1) ‘executive’ ownership of the issue, (2) consensus prescribing guidelines, (3) a local formulary with various levels of restricted access, (4) a local champion (or champions) who is a trusted peer, (5) authority to intervene in prescribing and/or dispensing, (6) authority for measurement of use, audit and feedback, and (7) access to reliable laboratory services and their cumulative resistance data. Stewardship programs are most advanced in larger public hospitals, but there is considerable interest and need for developing programs tailored to a wide range of settings in human and animal health, each with their own particular characteristics of access to antimicrobials and potential controls. The potential value of stewardship in food animal production is now recognised globally, and Australia has taken the first steps towards surveillance and stewardship in this sector, supported by a recently released national One Health strategy on the containment of antimicrobial resistance.
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Halpin, Kim, Kerryne Graham und Peter A. Durr. „Sero-Monitoring of Horses Demonstrates the Equivac® HeV Hendra Virus Vaccine to Be Highly Effective in Inducing Neutralising Antibody Titres“. Vaccines 9, Nr. 7 (02.07.2021): 731. http://dx.doi.org/10.3390/vaccines9070731.

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Hendra virus (HeV) is a high consequence zoonotic pathogen found in Australia. The HeV vaccine was developed for use in horses and provides a One Health solution to the prevention of human disease. By protecting horses from infection, the vaccine indirectly protects humans as well, as horses are the only known source of infection for humans. The sub-unit-based vaccine, containing recombinant HeV soluble G (sG) glycoprotein, was released by Pfizer Animal Health (now Zoetis) for use in Australia at the end of 2012. The purpose of this study was to collate post-vaccination serum neutralising antibody titres as a way of assessing how the vaccine has been performing in the field. Serum neutralization tests (SNTs) were performed on serum samples from vaccinated horses submitted to the laboratory by veterinarians. The SNT results have been analysed, together with age, dates of vaccinations, date of sampling and location. Results from 332 horses formed the data set. Provided horses received at least three vaccinations (consisting of two doses 3–6 weeks apart, and a third dose six months later), horses had high neutralising titres (median titre for three or more vaccinations was 2048), and none tested negative.
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Sendow, Indrawati, und Raden Mohamad Abdul Adjid. „Infeksi Virus Peste de Petits Ruminants (PPR) pada Kambing dan Domba di Indonesia“. Jurnal Sain Veteriner 35, Nr. 2 (12.04.2018): 165. http://dx.doi.org/10.22146/jsv.34665.

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Peste des petits ruminants (PPR) merupakan salah satu penyakit virus pada kambing dan domba yang ditandai dengan peradangan pada saluran pencernaan dan pernafasan. Penyakit ini masuk dalam “daftar penyakit” yang dibuat oleh OIE. Keberadaan penyakit ini di Indonesia belum pernah dilaporkan sehingga perlu dilakukan surveilan secara serologis pada kambing dan domba untuk mendapatkan informasi awal keberadaan antibodi terhadap virus PPR. Sebanyak 680 sampel serum kambing dan domba yang berasal dari Rumah Potong Hewan (RPH) Jakarta dan pedagang/pengumpul kambing dan domba di Jakarta pada tahun 2014 telah dikoleksi. Hasil pengujian dengan uji kompetitif ELISA yang menggunakan antigen inaktif (recombinant nucleoprotein- NP), menunjukkan bahwa telah terdeteksi antibodi terhadap virus PPR dengan prevalensi 0,2% pada kambing dan 1,7 % pada domba asal RPH Jakarta. . Berdasarkan lokasi asal ternak yang masuk ke RPH Jakarta, prevalensi tertinggi diperoleh dari Indramayu (2,8%), Solo 0.75%. Serum yang positif, beberapa negatif dan dubius tersebut kemudian diuji untuk dikonfirmasi di Australian Animal Health Laboratory (AAHL) menggunakan uji ELISA dan menunjukkan hasil yang konsisten yaitu tetap positif atau negatif. Selanjutnya dilakukan pengambilan sampel serum dari domba dan kambing di beberapa kabupaten Indramayu pada tahun 2016. Hasil menunjukkan bahwa seluruh sampel sebanyak 326 sera telah diuji dengan uji ELISA hasilnya negatif. Hasil penelitian ini memperlihatkan bahwa infeksi PPR masih sangat rendah, namun hasil ini dapat menunjukkan indikasi awal adanya infeksi PPR di Indonesia. Oleh karena itu, kewaspadaan terhadap meningkatnya kejadian infeksi PPR di Indonesia perlu mendapat perhatian.
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Nicholas, Robin A. J. „Contagious Bovine Pleuropneumonia: A Passage to India“. Animals 13, Nr. 13 (29.06.2023): 2151. http://dx.doi.org/10.3390/ani13132151.

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The World Organization for Animal Health (WOAH)-listed contagious bovine pleuropneumonia (CBPP) emerged first in Europe and then spread to Eastern Asia, including Japan and China, from the Northern Territories of Australia at the end of the 19th century. Its route to India, however, is less well known as there is little evidence for large importations of cattle from Australia. The lack of accurate diagnostic tests at this time meant veterinary authorities relied solely on clinical and pathological signs, many of which were non-specific. Consequently, any diagnoses of CBPP reported in the early 20th century must be viewed with caution. More convincing reports of CBPP confirmed by laboratory tests were made in the 1930s and 1940s in the Indian state of Assam. Eradication campaigns began in the 1940s with immunizations of live attenuated vaccines and then more comprehensively in the 1950s and 1960s, supplemented with serological screening and the establishment of quarantine centres at international borders. The last case of CBPP, reported to WOAH, was seen in 1990, but the launch of a new awareness campaign in Assam in 2002 and recent reports of the disease in Pakistan suggests the disease has persisted in the Indian subcontinent well into the 21st century.
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Dhileepan, Kunjithapatham. „Reproductive Variation in Naturally Occurring Populations of the Weed Parthenium hysterophorus (Asteraceae) in Australia“. Weed Science 60, Nr. 4 (Dezember 2012): 571–76. http://dx.doi.org/10.1614/ws-d-12-00005.1.

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Parthenium weed, an annual herb native to tropical America, causes severe economic, human, and animal health and environmental impacts in Australia and in many countries in Asia, Africa, and the Pacific. There is little known about variation in reproductive output in naturally occurring populations of this weed. This information is vital to develop plant population models, devise management strategies to reduce seed output, and formulate parthenium weed pollen-induced human health (e.g., dermatitis and hay fever) risk assessment. Here, the variations in the number of capitula produced by the parthenium weed at two sites in Queensland, Australia, over a 4-yr period are reported. Under field conditions, parthenium weed produced up to 39,192 capitula per plant (> 156,768 seeds per plant), with majority of the plants (≈ 75%) producing between 11 and 1,000 capitula, and less than 0.3% of the plants producing more than 10,000 capitula (> 40,000 seeds per plant). The number of capitula per plant in the field (297 ± 22) was much lower than those reported from glasshouse and laboratory studies. Plant biomass contributed to 50 to 80% of the variation in capitulum production between plants within plots at each site, and weed density accounted for 62 to 73% of the variation in capitulum production between plots within each site. As plant size is directly correlated with reproductive output, plant size distributions in parthenium weed can be used to estimate effective population size. Information on variation in reproductive output will be used to implement management strategies to reduce parthenium weed seed output, resulting in reduced soil seed bank and weed seed spread.
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Weyl, Philip, Abdul Rehman und Kazam Ali. „The Host Range of the Stem-Boring Weevil, Listronotus setosipennis (Coleoptera: Curculionidae) Proposed for the Biological Control of Parthenium hysterophorus (Asteraceae) in Pakistan“. Insects 12, Nr. 5 (17.05.2021): 463. http://dx.doi.org/10.3390/insects12050463.

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Parthenium, or Parthenium hysterophorus, has extended its range in Pakistan throughout Punjab and into Khyber Pakhtunkhwa, the Federally Administrated Tribal Areas, Azad Jammu and Kashmir, and Sindh Provinces. Without control measures against parthenium, the negative impacts of this weed will go unchecked having deleterious effects on native biodiversity, human and animal health, as well as crop productivity. The weevil Listronotus setosipennis was obtained and imported from the Plant Health and Protection of the Agricultural Research Council (ARC-PHP), in Cedara, South Africa, in April 2019. A total of 22 plant species or cultivars in the Asteraceae family were assessed during no-choice oviposition tests in Pakistan. During these tests, the only plant species accepted for oviposition were the 10 cultivars of Helianthus annuus that are grown in Pakistan. All cultivars were thus tested for development of L. setosipennis from egg to adult. Only three cultivars were able to support some larval development, but at such low levels that it is unlikely to be the basis of a viable population. To support this, a risk assessment was conducted to ascertain the probability of L. setosipennis being able to sustain viable populations in the field, the results of which concur with native (Argentina) and introduced (Australia) field host-range information where L. setosipennis has never been recorded as a pest of sunflowers. The results of laboratory-based host-range trials, together with host records from its native and introduced range, indicate that L. setosipennis is sufficiently specific to parthenium and is thus suitable for release in Pakistan.
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Norman, Hayley C., Angelo Loi, Matt G. Wilmot, Allan J. Rintoul, Bradley J. Nutt und Clinton K. Revell. „Sheep grazing bladder clover (Trifolium spumosum L.) had similar productivity and meat quality to sheep grazing subterranean clover (Trifolium subterraneum L.)“. Animal Production Science 53, Nr. 3 (2013): 209. http://dx.doi.org/10.1071/an12185.

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An accession of bladder clover, a new species to agriculture, was selected for commercial release in Australia with the cultivar name of AGWEST Bartolo. As part of a duty-of-care assessment, we tested the hypothesis that sheep grazing the bladder clover cultivar will have similar liveweight, condition scores and wool production to sheep grazing a widely adopted subterranean clover cultivar (cv. Dalkeith). Further, we hypothesised that sheep grazing bladder clover and subterranean clover will have similar meat quality (after 48 days of grazing) and health as indicated by muscle, liver and kidney panel analysis. The data supported the hypotheses. While there were significant initial differences in liveweight between the two groups of sheep, there were no significant differences in liveweight at later time points during the grazing period and no significant differences in mean daily growth rate between weighing times. There were no differences in wool growth between sheep grazing the bladder or subterranean clover cultivars. Sheep in the subterranean clover plots had significantly higher condition scores after the first 24 days of grazing; however, these differences were not apparent after another 24 days of grazing. There were some differences in indications of animal health; however, there were no significant detrimental effects associated with bladder clover and sheep grazing both species had mean plasma indicators that were deemed ‘healthy’. There were no differences in meat eating quality as estimated by a consumer panel for tenderness, juiciness or flavour. Dry seasonal conditions limited biomass growth and the sheep were removed from the subterranean clover plots on Day 48 of grazing. The sheep grazing the bladder clover plots remained on the plots for a further 26 days. The data indicate that, for the conditions of this experiment, the clovers had the same relative feeding value. Laboratory analysis of herbage from across the clover plots (bulked before analysis) suggest that the bladder clover had higher in vitro digestibility, crude protein and lower fibre than the herbage sample from the subterranean clover plots. The biomass data indicate that the bladder clover cultivar can support more grazing days per ha in a relatively dry season than the subterranean clover cultivar.
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Morris, Tim. „Laboratory animal health monitoring“. Laboratory Animals 33, Nr. 1_suppl (Januar 1999): 1–2. http://dx.doi.org/10.1258/002367799780639978.

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25

Eisenberg, Tobias, Stefanie P. Glaeser, Christa Ewers, Torsten Semmler, Werner Nicklas, Jörg Rau, Norman Mauder et al. „Streptobacillus notomytis sp. nov., isolated from a spinifex hopping mouse (Notomys alexis Thomas, 1922), and emended description of Streptobacillus Levaditi et al. 1925, Eisenberg et al. 2015 emend.“ International Journal of Systematic and Evolutionary Microbiology 65, Pt_12 (01.12.2015): 4823–29. http://dx.doi.org/10.1099/ijsem.0.000654.

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A pleomorphic, Gram-negative, rod-shaped, indole-, oxidase- and catalase-negative, non-spore-forming, non-motile bacterium was isolated in 1979 from the heart of a spinifex hopping mouse (Notomys alexis Thomas, 1922) with septicaemia and stored as Streptobacillus moniliformis in the strain collection of the Animal Health Laboratory, South Perth, Western Australia (AHL 370-1), as well as under CCUG 12425. On the basis of 16S rRNA gene sequence analyses, the strain was assigned to the genus Streptobacillus, with 99.4 % sequence similarity to the type strain of Streptobacillus moniliformis, 95.6 % sequence similarity to the type strain of Streptobacillus hongkongensis and 99.0 % sequence similarity to the type strain of Streptobacillus felis. The clear differentiation of strain AHL 370-1T from Streptobacillus moniliformis, Streptobacillus hongkongensis and Streptobacillus felis was also supported by rpoB, groEL and recA nucleotide and amino acid sequence analysis. Average nucleotide identity was 87.16 % between strain AHL 370-1T and Streptobacillus moniliformis DSM 12112T. Physiological data confirmed the allocation of strain AHL 370-1T to the family Leptotrichiaceae, considering the very similar profiles of enzyme activities and fatty acids compared to closely related species. Within the genus Streptobacillus, isolate AHL 370-1T could also be separated unambiguously from the type strains of Streptobacillus moniliformis, Streptobacillus hongkongensis and Streptobacillus felis by MALDI-TOF mass spectrometry. Two further strains (KWG2 and KWG24) isolated from asymptomatic black rats in Japan were highly similar to AHL 370-1T. On the basis of these data, we propose the novel species Streptobacillus notomytis sp. nov., with the type strain AHL 370-1T ( = CCUG 12425T = DSM 100026T = CCM 8593T = EF 12425T).
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Klempfner, G. „Recommendation from Australian Radiation Laboratory“. Journal of Paediatrics and Child Health 21, Nr. 2 (Mai 1985): 137–38. http://dx.doi.org/10.1111/j.1440-1754.1985.tb00147.x.

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27

Acton, Debra, und Linda McCauley. „Laboratory Animal Allergy“. AAOHN Journal 55, Nr. 6 (Juni 2007): 241–44. http://dx.doi.org/10.1177/216507990705500604.

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28

CULLEN, G. A. „Health and safety in laboratory animal facilities (Laboratory animal handbooks No 13)“. Occupational and Environmental Medicine 58, Nr. 4 (01.04.2001): 280. http://dx.doi.org/10.1136/oem.58.4.280.

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29

Stave, Gregg M., Edward H. Lee und Dennis J. Darcey. „Laboratory Animal Bite Anaphylaxis“. Journal of Occupational and Environmental Medicine 59, Nr. 8 (August 2017): 728–38. http://dx.doi.org/10.1097/jom.0000000000001005.

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30

Stave, Gregg M., Edward H. Lee und Dennis J. Darcey. „Laboratory Animal Bite Anaphylaxis“. Journal of Occupational and Environmental Medicine 59, Nr. 8 (August 2017): 739–41. http://dx.doi.org/10.1097/jom.0000000000001063.

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31

Fisher, Robin, William B. Saunders, Steven J. Murray und Gregg M. Stave. „Prevention of Laboratory Animal Allergy“. Journal of Occupational & Environmental Medicine 40, Nr. 7 (Juli 1998): 609–13. http://dx.doi.org/10.1097/00043764-199807000-00005.

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32

Gordon, S. „Prevention of laboratory animal allergy“. Occupational Medicine 53, Nr. 6 (01.09.2003): 371–77. http://dx.doi.org/10.1093/occmed/kqg117.

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33

E. Dyson, Susan, und Michael C. Calver. „The value of Animal Ethics Committees for wildlife research in conservation biology - an Australian perspective“. Pacific Conservation Biology 9, Nr. 2 (2003): 86. http://dx.doi.org/10.1071/pc030086.

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ANIMAL Ethics Committees evaluate research proposals according to the Australian Code of Practice for the Care and Use of Animals for Scientific Purposes (NHMRC 1997). All Australian universities, the CSIRO, many agencies controlled by the states and other organizations adhere to the specifications. The 1997 revision of the Code of Practice explicitly broadened its scope from laboratory animals to include field-based ecological studies, such as those conducted by conservation biologists. However, in defining an animal as "any live non-human vertebrate" invertebrates are excluded by the Code.
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34

Jones, RE. „Phenotypic Variation in Australian Eurema Species“. Australian Journal of Zoology 40, Nr. 4 (1992): 371. http://dx.doi.org/10.1071/zo9920371.

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Australian butterflies in the tropical pierid genus Eurema (the grass yellows) exhibit seasonal phenotypic changes in both size and colour pattern. In four of the five species, smaller adults were present during the summer and autumn wet season than during the cooler winter-spring dry season. The fifth species, E. hecabe, showed the reverse pattern, being largest when it first appeared late in the wet season and becoming smaller as the dry season progressed. When reared in the laboratory, however, all five species produced larger adults when reared at lower temperatures, and at least two of the species also produced larger adults at shorter photoperiods. In the case of E. hecabe, juvenile overcrowding and resource limitation may prevent the potential size increase during the cooler dry season from occurring. All five species had darker markings during the cooler dry season, and in two of them, E. herla and E. laeta, there was also a change in the ground colour of the underwing from yellow to pink or brown. The darker markings may serve a thermoregulatory function, as in other pierids, but the change in colour probably functions to allow E. herla and E. laeta, which diapause as adults during the dry season, to be more cryptic as the grasslands they occupy dry off and change colour. In all species except E. herla, the range of variation in dark markings observed in the field could be reproduced in the laboratory by varying the temperatures and/or photoperiods at which the juvenile stages were reared (darker individuals were produced at lower temperatures and shorter photoperiods). The change in ground colour in E. herla and E. laeta, however, was not reproduced in laboratory rearings, either by changing photoperiod and temperatures, or by rearing animals at low humidities, suggesting that an additional cue may be needed to induce this shift in phenotype.
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35

Agrup, G., L. Belin, L. Sjostedt und S. Skerfving. „Allergy to laboratory animals in laboratory technicians and animal keepers.“ Occupational and Environmental Medicine 43, Nr. 3 (01.03.1986): 192–98. http://dx.doi.org/10.1136/oem.43.3.192.

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36

Mok, Dennis. „The army laboratory response“. Microbiology Australia 26, Nr. 4 (2005): 162. http://dx.doi.org/10.1071/ma05162.

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At the request of the Indonesian government, the 1st Health Support Battalion was given the task of providing immediate medical support as part of the Australian government program of humanitarian relief following the tsunami that devastated areas of the Indonesian island of Sumatra on 26 December 2004.
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37

Venables, K. M., J. L. Upton, E. R. Hawkins, R. D. Tee, J. L. Longbottom und A. J. Newman Taylor. „Smoking, atopy, and laboratory animal allergy.“ Occupational and Environmental Medicine 45, Nr. 10 (01.10.1988): 667–71. http://dx.doi.org/10.1136/oem.45.10.667.

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38

Weiss, Bernard, Sander Stern, Elsa Cernichiari und Robert Gelein. „Methylmercury Contamination of Laboratory Animal Diets“. Environmental Health Perspectives 113, Nr. 9 (September 2005): 1120–22. http://dx.doi.org/10.1289/ehp.7816.

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39

Withnall, Kay. „Transition and beyond in the laboratory“. Microbiology Australia 26, Nr. 4 (2005): 172. http://dx.doi.org/10.1071/ma05172.

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Following the deployment of the emergency Australian medical teams, in early March Interplast Australia and International SOS were contracted to provide and manage an Australian-Indonesian medical team to assist the general hospital in Banda Aceh reestablish services and provide on-the-job training. The size of the team varied between 20 and 26 members over the months of the contract. The majority were Indonesian who, with their experience of working in Indonesia, knowledge of the health system, language skills and cultural sensitivity, were essential to the success of the program.
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KOSTOMITSOPOULOS (Ν.Γ. ΚΩΣΤΟΜΗΤΣΟΠΟΥΛΟΣ), N. G. „Laboratory animal facility management“. Journal of the Hellenic Veterinary Medical Society 55, Nr. 3 (06.12.2017): 268. http://dx.doi.org/10.12681/jhvms.15116.

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The successful management of a laboratory animal facility is based on the design and implementation of a management program, which in most cases covers the minimum legislative requirements and goes further, in order to achieve more in the field of animal welfare. A complete management program should consist of the following main points: a) Monitoring of animal housing, the macro- and microenvironment of the animals, b) veterinary medical care, c) monitoring of electromechanical equipment and the overall construction of the animal facility, and designing of emergency and disaster plans, d) monitoring of the overall program by the Institutional Animal Care and Use Committee responsible to oversee and evaluate the management program of the facility, e) education and training of personnel and f) the implementation of an occupational health and safety program.
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41

Tidemann, Christopher, Michael Vardon, John Nelson, Richard Speare und Laurence Gleeson. „Health and conservation implications of Australian batLyssavirus“. Australian Zoologist 30, Nr. 3 (März 1997): 369–76. http://dx.doi.org/10.7882/az.1997.015.

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42

Pellizzon, Michael. „Choice of laboratory animal diet influences intestinal health“. Lab Animal 45, Nr. 6 (20.05.2016): 238–39. http://dx.doi.org/10.1038/laban.1014.

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43

W Smith, David. „Bioterrorism preparedness and the Public Health Laboratory Network (PHLN)“. Microbiology Australia 24, Nr. 2 (2003): 20. http://dx.doi.org/10.1071/ma03220.

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The anthrax events that occurred in the USA in 2001 demonstrated that bioterrorism remains a real possibility in the modern world. Although Australia was spared the genuine anthrax events, we did experience many hoax events and massive disruption. Biological agents can cause terror not only by the real risk when one is released, but also by the social and economic disruption resulting from credible threats. Laboratory capacity is fundamental to the bioterrorist response and members of the Public Health Laboratory Network (PHLN) had a major role in the Australian white powder incidents.
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44

Venables, K. M., R. D. Tee, E. R. Hawkins, D. J. Gordon, C. J. Wale, N. M. Farrer, T. H. Lam, P. J. Baxter und A. J. Newman Taylor. „Laboratory animal allergy in a pharmaceutical company.“ Occupational and Environmental Medicine 45, Nr. 10 (01.10.1988): 660–66. http://dx.doi.org/10.1136/oem.45.10.660.

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45

Preece, R. M. „Lung function decline in laboratory animal workers“. Occupational and Environmental Medicine 61, Nr. 5 (01.05.2004): 475. http://dx.doi.org/10.1136/oem.2003.011767.

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46

Priyantha, M. A. R. „Francisella tularensis: a zoonotic pathogen among wild rodents and arthropods - a possible threat in future“. Sri Lanka Veterinary Journal 70, Nr. 1 (06.09.2023): 13–21. http://dx.doi.org/10.4038/slvj.v70i1.76.

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Francisella tularensis is a Gram-negative coccobacillus and an aerobic bacterium. It causes a zoonotic disease called tularemia in humans. Four subspecies have been found in F. tularensis as F. tularensis subsp. Tularensis (Type A strains), F. tularensis subsp. Holarctica (Type B strains), F. tularensis subsp. mediasiatica, and F. tularensis subsp. Novicida. Rearing rabbits and different kinds of rodents as pets are becoming popular in Sri Lanka, veterinarians need to be knowledgeable on emerging pathogens such as F. tularensis, to diagnose the disease within a short time. Therefore, the objective of this paper is to update veterinarians on possible emerging infections to improve the health of pets and to minimize possible zoonotic infections. The clinical outcome caused by Francisella is a debilitating febrile disease in humans. Francisella has been isolated from hundreds of animal species in the world. Being a diverse host range, associated ecological factors relating transmission of Francisella in the environment is largely unknown. F. tularensis type A was reported to be common in North America while occasionally found in Europe. Type B was found commonly in the Northern hemisphere and in Australia. Tularemia is a sporadic disease, and a small infectious dose is required for an infection in humans. The clinical signs and symptoms of tularaemia depend on the route of infection. Six types of clinical forms were identified as ulceroglandular, glandular, oropharyngeal, oculoglandular, pneumonic and typhoidal in humans. Diagnosis of tularemia in humans is based on epidemiology, clinical findings and laboratory confirmation. Microagglutination test, indirect immunofluorescence assay (IFA) and Enzymelinked immunosorbent assay ELISA are widely used as diagnostic tests. Several conventional and qPCR have been optimized to detect the organism in clinical samples. Antimicrobials such as aminoglycosides, tetracycline, quinolones, and chloramphenicol were used to minimize clinical complications. Utilization of treated water, usage of gloves on handling wild rabbits and rodents, thorough cooking of bush meat, usage of insect repellents, protection of stored food from rodents, wearing masks, ticks-free clothes, keeping away from weeds, cleaning pets from external parasites have been identified as the main preventive strategies against tularaemia in human. No commercial vaccine is found in the market yet against F. tularensis. This can be an emerging and threatening disease in the future with ongoing changes in arthropod parasites in the ecosystem followed by climatic changes in the world.
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47

Elson, Denise. „Proposed changes to the Australian Standard for microbiological safety in laboratories (AS/NZS 2243.3)“. Microbiology Australia 29, Nr. 2 (2008): 66. http://dx.doi.org/10.1071/ma08066.

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The Australian/New Zealand Standard for safety in microbiological laboratories and containment facilities, AS/NZS 2243.3:20021, is currently undergoing revision. This update reflects requirements for the safe handling of microorganisms in all four containment levels of laboratories and containment facilities (PC1-4); it also covers the requirements for animal, plant and invertebrate containment facilities. The committee has endeavoured to ensure harmonisation with publications by the Office of the Gene Technology Regulator (OGTR) and Australian Quarantine and Inspection Service (AQIS) to facilitate implementation by laboratory managers and scientists.
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48

Williams, JB, PC Withers, SD Bradshaw und KA Nagy. „Metabolism and Water Flux of Captive and Free-Living Australian Parrots“. Australian Journal of Zoology 39, Nr. 2 (1991): 131. http://dx.doi.org/10.1071/zo9910131.

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Occupation of desert environments often requires evolutionary specialisations that minimise food and water requirements. One physiological adjustment to living in a hot, dry climate that has been found in several laboratory studies of birds is a reduced basal metabolic rate (BMR), which often translates into a diminished rate of evaporative water loss (EWL). In free-living birds, these physiological traits are thought to result in a lower field metabolic rate and water flux. We studied metabolism and water flux of a number of species of Australian parrots, both in the laboratory and in the field. After combining our laboratory data with values from the literature, we performed allometric analyses to search for evolutionary specialisation in metabolism and water flux in desert-adapted parrots. Our data do not support the idea that parrots living in arid environments have a reduced BMR. Field metabolic rates of parrots from western Australia were indistinguishable from those of other nonpasserine birds. Laboratory EWL was significantly lower for parrots living in desert environments than for those occupying more mesic habitats, and often lower than that expected from body size. Some species of parrots that live in desert regions of Australia have evolved mechanisms that reduce EWL, but this does not involve a reduction in BMR. In the field, parrots living in Western Australia had a lower water influx than predicted for nonpasserines, but this did not approach the value often found in other desert-adapted species. Values for the water economy index (water flux in free-living animals relative to their energy metabolism) were among the lowest that have been reported for desert-adapted birds.
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49

Krop, E. J. M., G. Doekes, M. J. Stone, R. C. Aalberse und J. S. van der Zee. „Spreading of occupational allergens: laboratory animal allergens on hair-covering caps and in mattress dust of laboratory animal workers“. Occupational and Environmental Medicine 64, Nr. 4 (20.12.2006): 267–72. http://dx.doi.org/10.1136/oem.2006.028845.

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50

Riley, Tamara, Bonny Cumming, Joanne Thandrayen, Anna Meredith, Neil E. Anderson und Raymond Lovett. „One Health and Australian Aboriginal and Torres Strait Islander Communities: A One Health Pilot Study“. International Journal of Environmental Research and Public Health 20, Nr. 14 (20.07.2023): 6416. http://dx.doi.org/10.3390/ijerph20146416.

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Many Aboriginal and Torres Strait Islander communities face barriers in accessing animal healthcare and are exposed to disproportionate environmental health exposures leading to increased risk of disease. A One Health approach has been promoted to address public health risks and improve human, animal, and environmental health outcomes in communities. We undertook a pilot One Health study in Aboriginal and Torres Strait Islander communities in Queensland collecting animal, human, and environmental health data from 82 households. We performed a descriptive analysis and assessed the association between human and environmental health exposures and animal health outcomes. Most households were not crowded (82.9%) but did report a high level of environmental health concerns (86.6%). The majority of households owned cats and dogs (81.7%), with most animals assessed as healthy. There was no association between human and environmental health exposures and animal health outcomes. As most households experienced concerns regarding housing conditions, environmental health programs should prioritise improving household factors. There was also strong support for animal healthcare (including access to medicines and veterinarians, education programs and population management), indicating that a One Health approach is desired by communities.
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