Thematische Bibliographien / Aortic blood

Inhaltsverzeichnis

  1. Zeitschriftenartikel
  2. Dissertationen
  3. Bücher
  4. Buchteile
  5. Konferenzberichte
  6. Berichte der Organisationen

Auswahl der wissenschaftlichen Literatur zum Thema „Aortic blood“

Autor: Grafiati
Veröffentlicht am 4. Juni 2021
Zuletzt aktualisiert am 21. Februar 2023

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Zeitschriftenartikel zum Thema "Aortic blood"

1

Laurent, Stéphane, Pierre Boutouyrie und Elie Mousseaux. „Aortic Stiffening, Aortic Blood Flow Reversal, and Renal Blood Flow“. Hypertension 66, Nr. 1 (Juli 2015): 10–12. http://dx.doi.org/10.1161/hypertensionaha.115.05357.

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Muchada, Raoul, Dominique Cathignol, Bernard Lavandier, Jean Lamazou und Dominique Haro. „Aortic Blood Flow Measurement“. American Journal of Noninvasive Cardiology 2, Nr. 1-2 (1988): 24–31. http://dx.doi.org/10.1159/000470655.

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3

Gjurich, Breanne, Parésa Taghavie-Moghadam, Klaus Ley und Elena Galkina. „L-selectin deficiency decreases aortic B1a and Breg subsets and promotes atherosclerosis“. Thrombosis and Haemostasis 112, Nr. 10 (2014): 803–11. http://dx.doi.org/10.1160/th13-10-0865.

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SummaryThere is a significant recruitment of leucocytes into aortas during atherogenesis. L-selectin regulates leucocyte migration into secondary lymphoid and peripheral tissues and was proposed to play a role in leucocyte homing into aortas. Here, we determine the role of L-selectin in atherosclerosis. L-selectin-deficient Apoe -/- (Sell -/- Apoe -/-) mice had a 74% increase in plaque burden compared to Apoe -/- mice fed a chow diet for 50 weeks. Elevated atherosclerosis was accompanied by increased aortic leucocyte content, but a 50% reduction in aortic B cells despite elevated B cell counts in the blood. Follicular B cells represented 65%, whereas B1a and regulatory B cells (Breg) comprised 5% of aortic B cells. B1a and Breg cell subsets were reduced in Sell -/- Apoe -/- aortas with accompanied two-fold decrease in aortic T15 antibody and 1.2-fold decrease of interleukin-10 (IL-10) levels. L-selectin was required for B1 cell homing to the atherosclerotic aorta, as demonstrated by a 1.5-fold decrease in the migration of Sell -/- Apoe -/- vs Apoe -/- cells. Notably, we found a 1.6-fold increase in CD68hi macrophages in Sell -/- Apoe -/- compared to Apoe -/- aortas, despite comparable blood monocyte numbers and L-selectin-dependent aortic homing. L-selectin had no effect on neutrophil migration into aorta, but led to elevated blood neutrophil numbers, suggesting a potential involvement of neutrophils in atherogenesis of Sell -/- Apoe -/- mice. Thus, L-selectin deficiency increases peripheral blood neutrophil and lymphocyte numbers, decreases aortic B1a and Breg populations, T15 antibody and IL-10 levels, and increases aortic macrophage content of Sell -/- Apoe -/- mice. Altogether, these data provide evidence for an overall atheroprotective role of L-selectin.
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R, VINOTH. „TRANSIENT ANALYSIS OF BLOOD FLOW IN FUSIFORM MODELS OF AORTIC ANEURYSMS“. International Journal of Psychosocial Rehabilitation 24, Nr. 04 (29.02.2020): 1450–62. http://dx.doi.org/10.37200/ijpr/v24i4/pr201114.

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Lehmann, E. D., K. D. Hopkins, R. L. Jones, A. G. Rudd und R. G. Gosling. „Aortic Distensibility in Patients with Cerebrovascular Disease“. Clinical Science 89, Nr. 3 (01.09.1995): 247–53. http://dx.doi.org/10.1042/cs0890247.

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1. Non-invasive aortic compliance measurements have been used previously to assess the distensibility of the aorta in several pathological conditions associated with increased cardiovascular risk. We set out to establish whether aortic compliance is abnormal in patients with stroke. 2. Pulse wave velocity measurements of thoracoabdominal aortic compliance were made in 20 stroke patients and 25 age- and sex-matched hospitalized, non-stroke control subjects putatively free of cardiovascular disease. Since compliance varies with non-chronic changes in blood pressure, a blood pressure corrected index of aortic distensibility, Cp, was calculated. 3. Aortic compliance was significantly reduced in patients with stroke compared with non-stroke control subjects (0.46 ± 0.27 versus 0.86 ± 0.34%/10 mmHg, P < 0.0002), corresponding with higher values for pulse wave velocity. Stroke patients also had significantly higher systolic and diastolic blood pressures (P < 0.02 and P < 0.002 respectively) and total cholesterol levels (P < 0.004) than the control subjects. Calculation of Cp did not alter the observation of stiffer aortas in the stroke cohort (P < 0.0007). 4. In both stroke patient and control cohorts, as expected, inverse trends were observed between aortic compliance and blood pressure. Also as expected, in the control group Cp values did not show a relationship with blood pressure (r = 0.02, P = 0.092, not significant). However, in the stroke cohort a marked dependence of Cp on blood pressure was observed (r = −0.48, P = 0.03). 5. Transoesophageal echocardiographic studies have recently identified advanced atherosclerosis in the ascending aorta as a possible source of cerebral emboli and an independent risk factor for ischaemic stroke. Our observations of significantly stiffer thoracoabdominal aortas in patients with stroke lead us to hypothesize that a totally non-invasive assessment of aortic compliance may potentially prove a useful surrogate marker of such atherosclerotic risk. 6. Blood pressure-corrected indices of arterial elastic properties based on normotensive models are widely applied in the literature. Our observation that these indices exhibit a considerable blood pressure dependence leads us to urge caution in the use of such corrections, especially in hypertensive patients.
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JONES, DAVID R., RICHARD W. BRILL und DENNIS C. MENSE. „The Influence of Blood Gas Properties on Gas Tensions and pH of Ventral and Dorsal Aortic Blood in Free-Swimming Tuna, Euthynnus Affinis“. Journal of Experimental Biology 120, Nr. 1 (01.01.1986): 201–13. http://dx.doi.org/10.1242/jeb.120.1.201.

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We have developed a technique for capture, anaesthetization, instrumentation and release of tuna and have made the first determinations of blood gas values in dorsal and ventral aortae of free-swimming tuna. Dorsal aortic Po2 varied from 34.5 to 91.7 mmHg, and Pcoco2 ranged from 3.7 to 7mmHg. Dorsal aortic blood [pHa = 7.77 ± 0.04 (8), mean ± one S.E.M. (N)] was more alkaline than ventral aortic blood [pHv = 7.65 ± 0.02 (7)]. Warming dorsal aortic blood from 25 to 35 °C in a closed system caused Po2 and PCOCO2 to rise and pH to fall. Oxygen-combining curves forwhole blood were sigmoid [mean Hill's number = 1.72 ± 0.05 (11), range 1.57-2.0]and P50 over the pH range found in free-swimming animals was 21 ± 1.75(8) mmHg. The CO2-induced Bohr coefficient (ΔlogP50/Δ pH) was −0.59 ± 0.046(30). Unusual features of CO2-combining curves are attributed to a significant Rooteffect. Although these in vitro properties of tuna whole blood are at variance withother published data on tuna they nevertheless substantiate our determinations madein vivo.
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Azam, M. A., und S. A. A. Salam. „Three Dimensional Analysis of the Blood Flow Regime within Abdominal Aortic Aneurysm“. International Journal of Engineering and Technology 3, Nr. 6 (2011): 621–27. http://dx.doi.org/10.7763/ijet.2011.v3.295.

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Bulpitt, Christopher J., C. Rajkumar und James D. Cameron. „Central aortic blood pressure measurements“. Journal of Human Hypertension 14, Nr. 8 (August 2000): 531. http://dx.doi.org/10.1038/sj.jhh.1001066.

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Bukoski, R. D., und D. A. McCarron. „Altered aortic reactivity and lowered blood pressure associated with high calcium intake“. American Journal of Physiology-Heart and Circulatory Physiology 251, Nr. 5 (01.11.1986): H976—H983. http://dx.doi.org/10.1152/ajpheart.1986.251.5.h976.

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The hypothesis that dietary calcium (dCa) alters functional properties of aortic smooth muscle in the spontaneously hypertensive rat (SHR) was tested. At 6 wk of age, Wistar Kyoto (WKY) and (SHR) rats were placed on a control diet containing 1% Ca. The experimental SHR group received a 2%-calcium diet. After an average of either 8 or 15 wk on the diets (WOD), aortic rings were prepared for measurement of passive elastic properties and isometric force development. Differences in blood pressure (BP) were not apparent until after 8 WOD when the BP of SHRs on 2% dCa were 10-15 mmHg lower than SHRs on 1% dCa (P less than 0.05). After 8 WOD, when the BP effect first emerged, no significant differences in aortic properties were observed between the SHR groups. However, after 15 WOD, aortas of SHRs on 2% dCa were more compliant than those of SHRs on 1% dCa and between 8 and 15 WOD the sensitivity to KCl decreased in aortas from the WKY group and the SHRs on 2% dCa, but not the SHR-1% dCa group (mean effective dose went from 14.4 +/- 0.4 to 18.5 +/- 0.9 mM for WKY and from 13.6 +/- 0.6 to 17.1 +/- 1.2 mM for SHRs on 2% dCa, P less than 0.05). In addition, between 8 and 15 WOD, a significant decrease in response to a calcium (Ca2+) challenge after removal of K+ and Ca2+ occurred in aortas of the SHRs on 2% dCa, but not in the control diet groups, indicating that a decrease in aortic reactivity was present in the Ca2+-supplemented SHR.(ABSTRACT TRUNCATED AT 250 WORDS)
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Zindovic, Igor, Gustaf Edgren, Shahab Nozohoor und Ammar Majeed. „ABO blood group and the risk of aortic disease: a nationwide cohort study“. BMJ Open 10, Nr. 10 (Oktober 2020): e036040. http://dx.doi.org/10.1136/bmjopen-2019-036040.

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ObjectivesTo analyse the association between ABO blood group and aortic disease using data on blood donors and transfused patients from Sweden.DesignThis was a retrospective study using data from the Swedish portion of the Scandinavian Donations and Transfusions Database. The association between ABO blood group and aortic disease was analysed using log-linear Poisson regression models and presented as incidence rate ratios (IRRs).SettingSwedish population-based study.ParticipantsThe study cohort consisted of 1 164 561 Swedish blood donors and 961 637 transfused patients with a combined follow-up time of 29 390 649 person-years.Primary and secondary outcome measuresIRRs of aortic events (ie, aortic aneurysms and/or aortic dissections) in relation to patient blood group.ResultsA total of 20 684 aortic events occurred during the study period. Non-O donors and patients had similar incidence of aortic events when compared with blood group O donors and patients with an IRR of 0.98 (95% CI, 0.93–1.04) and 1.00 (95% CI, 0.97–1.03), respectively. There were no differences between non-O and blood group O individuals when aortic dissections and aortic aneurysms were analysed separately. Blood group B conferred a lower risk of aortic aneurysms in the patient cohort when compared with blood group O (IRR, 0.90; 95% CI, 0.85–0.96).ConclusionsIn the present study, there were no statistically significant associations between ABO blood group and the risk of aortic disease. A possible protective effect of blood group B was observed in the patient cohort but this finding requires further investigation.
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Dissertationen zum Thema "Aortic blood"

1

Kattach, Hassan. „Blood pressure control in aortic stenosis“. Thesis, University of Oxford, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.526473.

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Andresen, Jean M. „Aortic Baroreceptor Reflex Control of Blood Pressure: Effect of Fitness“. Thesis, University of North Texas, 1992. https://digital.library.unt.edu/ark:/67531/metadc500922/.

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Aortic baroreflex (ABR) control of blood pressure was examined in 7 untrained (UT) and 8 endurance exercise trained (EET) young men. ABR control of blood pressure was determined during a steady state phenylephrine infusion to increase mean arterial pressure 10-15 mmHg, combined with positive neck pressure to counteract the increased carotid sinus transmural pressure, and low levels of lower body negative pressure to counteract the increased central venous pressure. Functioning alone, the ABR was functionally adequate to control blood pressure. However, ABR control of HR was significantly diminished in the EET subjects due solely to the decrease in the ABR sensitivity. The persistent strain from an increased stroke volume resulting from endurance exercise training could be the responsible mechanism.
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Lantz, Jonas. „On Aortic Blood Flow Simulations : Scale-Resolved Image-Based CFD“. Doctoral thesis, Linköpings universitet, Mekanisk värmeteori och strömningslära, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-85682.

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This thesis focuses on modeling and simulation of the blood flow in the aorta, the largest artery in the human body. It is an accepted fact that abnormal biological and mechanical interactions between the blood flow and the vessel wall are involved in the genesis and progression of cardiovascular diseases. The transport of low-density lipoprotein into the wall has been linked to the initiation of atherosclerosis. The mechanical forces acting on the wall can impede the endothelial cell layer function, which normally acts as a barrier to harmful substances. The wall shear stress (WSS) affects endothelial cell function, and is a direct consequence of the flow field; steady laminar flows are generally considered atheroprotective, while the unsteady turbulent flow could contribute to atherogenesis. Quantification of regions with abnormal wall shear stress is therefore vital in order to understand the initiation and progression of atherosclerosis.However, flow forces such as WSS cannot today be measured with significant accuracy using present clinical measurement techniques. Instead, researches rely on image-based computational modeling and simulation. With the aid of advanced mathematical models it is possible to simulate the blood flow, vessel dynamics, and even biochemical reactions, enabling information and insights that are currently unavailable through other techniques. During the cardiac cycle, the normally laminar aortic blood flow can become unstable and undergo transition to turbulence, at least in pathological cases such as coarctation of the aorta where the vessel is locally narrowed. The coarctation results in the formation of a jet with a high velocity, which will create the transition to turbulent flow. The high velocity will also increase the forces on the vessel wall. Turbulence is generally very difficult to model, requiring advanced mathematical models in order to resolve the flow features. As the flow is highly dependent on geometry, patient-specific representations of the in vivo arterial walls are needed, in order to perform an accurate and reliable simulation. Scale-resolving flow simulations were used to compute the WSS on the aortic wall and resolve the turbulent scales in the complex flow field. In addition to WSS, the turbulent flow before and after surgical intervention in an aortic coarctation was assessed. Numerical results were compared to state-of-the-art magnetic resonance imaging measurements. The results agreed very well, suggesting that that the measurement technique is reliable and could be used as a complement to standard clinical procedures when evaluating the outcome of an intervention.The work described in the thesis deals with patient-specific flows, and is, when possible, validated with experimental measurements. The results provide new insights to turbulent aortic flows, and show that image-based computational modeling and simulation are now ready for clinical practice.
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Kordzadeh, Ali. „Blood and blood component transfusion on 30-day mortality and morbidity of infra-renal ruptured abdominal aortic aneurysm“. Thesis, Anglia Ruskin University, 2017. http://arro.anglia.ac.uk/702581/.

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This thesis for the first time in the literature, through a single cohort (n=82), systematic review and meta-aggregation of the data, has identified that the majority (>85%) of ruptured abdominal aortic aneurysm (rAAA) do not present with coagulopathy. In addition, the thesis for the first time, through a retro and prospective cohort study, has demonstrated that the hemostatic resuscitation protocols derived from military and civilian trauma for the correction of coagulopathy with a blood product ratio of one unit of packed red blood cell to one unit of fresh frozen plasma to one pool of platelet (1:1:1), contributes to increased postoperative (30-day) morbidity and mortality, especially thrombotic complications. This was attributed to different baseline demographics, pathophysiology and coagulation status. Through a comparative study, the thesis then confirms that such transfusion practice not only contributes to adverse outcomes, but also has no impact on final coagulation status of rAAAs. In addition, through a retro and prospective cohort study, a novel hematological marker (neutrophil to lymphocyte ratio) (NLR) was identified as an independent predictor of morbidity in rAAAs. This thesis was set on the background of significant research into all factors that could contribute to pathogenesis, inhibition and progression of rAAAs. This thesis concludes that the use of additional blood products (fresh frozen plasma and platelet) in hemostatic resuscitation of ruptured abdominal aortic aneurysms alongside packed red blood cell is not evidence based and a single protocol derived from one cohort (military and civilian trauma) of patients does not apply to another. The use of additional products in ruptured abdominal aortic aneurysms should be tailored to the individual hematological and clinical requirements and not as a part of a set transfusion ratio (1:1:1). This thesis has resulted in a change of practice and has created a platform for further search of the optimal transfusion protocol in this cohort of patients.
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Kordzadeh, Ali. „Blood and blood component transfusion on 30-day mortality and morbidity of infra-renal ruptured abdominal aortic aneurysm“. Thesis, Anglia Ruskin University, 2017. https://arro.anglia.ac.uk/id/eprint/702581/1/Kordzadeh_2017.pdf.

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This thesis for the first time in the literature, through a single cohort (n=82), systematic review and meta-aggregation of the data, has identified that the majority (>85%) of ruptured abdominal aortic aneurysm (rAAA) do not present with coagulopathy. In addition, the thesis for the first time, through a retro and prospective cohort study, has demonstrated that the hemostatic resuscitation protocols derived from military and civilian trauma for the correction of coagulopathy with a blood product ratio of one unit of packed red blood cell to one unit of fresh frozen plasma to one pool of platelet (1:1:1), contributes to increased postoperative (30-day) morbidity and mortality, especially thrombotic complications. This was attributed to different baseline demographics, pathophysiology and coagulation status. Through a comparative study, the thesis then confirms that such transfusion practice not only contributes to adverse outcomes, but also has no impact on final coagulation status of rAAAs. In addition, through a retro and prospective cohort study, a novel hematological marker (neutrophil to lymphocyte ratio) (NLR) was identified as an independent predictor of morbidity in rAAAs. This thesis was set on the background of significant research into all factors that could contribute to pathogenesis, inhibition and progression of rAAAs. This thesis concludes that the use of additional blood products (fresh frozen plasma and platelet) in hemostatic resuscitation of ruptured abdominal aortic aneurysms alongside packed red blood cell is not evidence based and a single protocol derived from one cohort (military and civilian trauma) of patients does not apply to another. The use of additional products in ruptured abdominal aortic aneurysms should be tailored to the individual hematological and clinical requirements and not as a part of a set transfusion ratio (1:1:1). This thesis has resulted in a change of practice and has created a platform for further search of the optimal transfusion protocol in this cohort of patients.
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McGregor, Brian. „The left ventricle, aortic valve, and arterial tree - a fresh engineering perspective“. Thesis, University of Ulster, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.339346.

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Camacho, Fernando Graduate School of Biomedical Engineering Faculty of Engineering UNSW. „Statistical analysis of central aortic blood pressure parameters derived from the peripheral pulse“. Awarded by:University of New South Wales. Graduate School of Biomedical Engineering, 2006. http://handle.unsw.edu.au/1959.4/26215.

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With the rise in prevalence of cardiovascular (CV) disease, risk stratification is becoming increasingly important. Accurate characterization of the CV system is required, for which central aortic blood pressure (BP) parameters form an integral part. However, invasive measurement of central aortic BP parameters (aP) is difficult. Therefore, non-invasive methods to estimate aP from the radial pressure pulse (rPulse) have been proposed. To analyze accuracy of estimated aP (aPhat) and applicability in risk stratification and diagnosis, this study presents: (1) a novel representation of the rPulse with minimal loss of information, (2) a framework for strict definition and statistical analysis of aPhat, and (3) a dynamic analysis of effects of mean BP (MP) and heart rate (HR) in the rPulse shape. Methods: (1) 2671 rPulse s measured by applanation tonometry were represented using the first eight principal components (PC) scores after standard PC transformation. rPulse shapes were compared in three subpopulations. (2) The concept of "estimation option" (EO) for aP estimation was presented. A framework for strict definition of aPhat and the comparison of EOs was proposed, and 7 different EOs compared. (3) A sequence of rPulse s was analyzed during soft exhalation maneuver (SEM) %, a mild Valsalva type maneuver, in eight healthy subjects. Radial BP and respiration pressure were continuously measured. The effects of MP and HR in the rPulse parameters were analyzed by standard linear regression for each subject. Results: (1) PC representation of the rPulse improves accuracy of the estimation of aPhat compared with the simple use of rPulse parameters. Subpopulations have distinctive rPulse shapes. (2) No single EO was better for the estimation of all aPhat. Inclusion of MP improves estimation accuracy. Despite further improvement when rPulse is included, the general transfer function EO is a biased estimator. (3) The dynamic analysis of the rPulse provides information of the effects of MP and HR in the rPulse not available in static analysis. The effects were specific for each individual and different from the results obtained from a general population. Conclusions: For accurate CV risk stratification, future studies should include a dynamic measurement of calibrated radial pressure pulse during SEM maneuver. Risk analysis and diagnosis should be based on representations of the rPulse with minimum loss of information. aPhat should be used for better understanding of the underlying physiological principles.
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Cheng, Zhuo. „Analysis of blood flow in patient-specific models of type B aortic dissection“. Thesis, Imperial College London, 2012. http://hdl.handle.net/10044/1/9178.

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Aortic dissection is the most common acute catastrophic event affecting the aorta. The majority of patients presenting with an uncomplicated type B dissection are treated medically, but 25% of these patients develop subsequent dilatation and aortic aneurysm formation. The reasons behind the long‐term outcomes of type B aortic dissection are poorly understood. As haemodynamic factors have been involved in the development and progression of a variety of cardiovascular diseases, the flow phenomena and environment in patient‐specific models of type B aortic dissection have been studied in this thesis by applying computational fluid dynamics (CFD) to in vivo data. The present study aims to gain more detailed knowledge of the links between morphology, flow characteristics and clinical outcomes in type B dissection patients. The thesis includes two parts of patient‐specific study: a multiple case cross‐sectional study and a single case longitudinal study. The multiple cases study involved a group of ten patients with classic type B aortic dissection with a focus on examining the flow characteristics as well as the role of morphological factors in determining the flow patterns and haemodynamic parameters. The single case study was based on a series of follow‐up scans of a patient who has a stable dissection, with an aim to identify the specified haemodynamic factors that are associated with the progression of aortic dissection. Both studies were carried out based on computed tomography images acquired from the patients. 4D Phase‐contrast magnetic resonance imaging was performed on a typical type B aortic dissection patient to provide detailed flow data for validation purpose. This was achieved by qualitative and quantitative comparisons of velocity‐encoded images with simulation results of the CFD model. The analysis of simulation results, including velocity, wall shear stress and turbulence intensity profiles, demonstrates certain correlations between the morphological features and haemodynamic factors, and also their effects on long‐term outcomes of type B aortic dissections. The simulation results were in good agreement with in vivo MR flow data in the patient‐specific validation case, giving credence to the application of the computational model to the study of flow conditions in aortic dissection. This study made an important contribution by identifying the role of certain morphological and haemodynamic factors in the development of type B aortic dissection, which may help provide a better guideline to assist surgeons in choosing optimal treatment protocol for individual patient.
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Wolowczyk, Leszek. „Acute normovolaemic haemodilution in abdominal aortic aneurysm repair : the effect on systemic inflammatory response and clinical outcome“. Thesis, University of Bristol, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.271910.

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Kumar, Hemant, University of Western Sydney und of Science Technology and Environment College. „Software analytical tool for assessing cardiac blood flow parameters“. THESIS_FSTA_XXX_Kumar_H.xml, 2001. http://handle.uws.edu.au:8081/1959.7/392.

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Introduction of Doppler ultrasound techniques into the Intensive Care setting has revolutionised the way haemodynamic status is monitored in the critically ill. However, in order to increase the usefulness of these techniques, the Doppler signal and its spectrum need to be further analysed in ways to facilitate a better clinical response. Extensive processing of the Doppler spectrum on Diagnostic ultrasound machines is limited by the real time performance considerations. It was therefore proposed that the spectral information from these systems be extracted off-line and full set of analytical tools be made available to evaluate this information. This was achieved by creating an integrated and modular software tool called Spectron, which was intended as an aid in the overall management of the patients. The modular nature of Spectron was intended to ensure that new analytical tools and techniques could be easily added and tested. The software provides its users with considerable latitude in choosing various data acquisition and analysis parameters to suit various clinical situations and patient requirements. Spectron was developed under the Windows environment to provide a user friendly interface and to address a range of programming problems such as memory management and the size of the colour palettes. Spectron is able to detect the maximal velocities and compute the mean and median velocities. Relative increases in maximal velocities in cardiac blood flows after the administration of inotropic drugs have been shown in the pilot studies that were conducted. Spectron is able to help in obtaining estimates of the aortic blood flows and in other applications such measuring vascular impedance. Stenotic blood flows can be detected by using the spectral broadening index and blood flow characteristics can be studied by using various blood flow indices. Thus, this project attempted to help in patient management by providing clinicians with a range of blood flow parameters and has succeeded in meeting its objective to a large extent
Master of Engineering (Hons)
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Bücher zum Thema "Aortic blood"

1

Borst, H. G. Surgical treatment of aortic dissection. New York: Churchill Livingstone International, 1996.

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Shinichi, Takamoto, und SpringerLink (Online service), Hrsg. Advances in Understanding Aortic Diseases. Tokyo: Springer Japan, 2009.

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Klicpera, Martin. Chronic aortic regurgitation: Prognostic parameters for patients with chronic aortic regurgitation undergoing aortic valve replacement : value of invasive and non-invasive methods and pharmacological interventions (systemic vasodilation). Wien: Facultas Universitätsverlag, 1985.

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Enrique, Criado, und SpringerLink (Online service), Hrsg. Aortic Aneurysms: Pathogenesis and Treatment. Totowa, NJ: Humana Press, 2009.

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Clinical application of intra-aortic balloon pump. 3. Aufl. Armonk, N.Y: Futura Pub. Co., 1998.

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G, Hakaim Albert, Hrsg. Current endovascular treatment of abdominal aortic aneurysms. Oxford: Blackwell Pub., 2005.

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Morash, Mark D. Surgery of the aorta and its body branches. Shelton, Conn: People's Medical Pub. House-USA, 2010.

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Stoney, Ronald J. Wylie's atlas of vascular surgery. Philadelphia: J.B. Lippincott Co., 1992.

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Stoney, Ronald J. Wylie's atlas of vascular surgery. Philadelphia: Lippincott, 1993.

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Luther, Bernd, Ralph I. Ru ckert und Wolfgang Ru diger Hepp. Chirurgie der abdominalen und thorakalen Aorta. Berlin: Springer-Verlag, 2010.

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Buchteile zum Thema "Aortic blood"

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Singer, M. „Continuous Noninvasive Aortic Blood Flow Monitoring“. In Anaesthesia, Pain, Intensive Care and Emergency Medicine — A.P.I.C.E., 819–27. Milano: Springer Milan, 1996. http://dx.doi.org/10.1007/978-88-470-2203-4_76.

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von Knobelsdorff-Brenkenhoff, Florian, und Alex J. Barker. „4D Flow MR: Insights into Aortic Blood Flow Characteristics“. In Surgical Management of Aortic Pathology, 435–45. Vienna: Springer Vienna, 2019. http://dx.doi.org/10.1007/978-3-7091-4874-7_28.

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Melissano, Germano, Luca Bertoglio, Enrico Rinaldi und Roberto Chiesa. „Surgical Anatomy of the Blood Supply to the Spinal Cord“. In Surgical Management of Aortic Pathology, 1049–59. Vienna: Springer Vienna, 2019. http://dx.doi.org/10.1007/978-3-7091-4874-7_75.

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Reid, Amy J., und Dianna M. Milewicz. „Arteries, Smooth Muscle Cells and Genetic Causes of Thoracic Aortic Aneurysms“. In Inflammatory Diseases of Blood Vessels, 126–35. Oxford, UK: Wiley-Blackwell, 2012. http://dx.doi.org/10.1002/9781118355244.ch12.

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Vasava, P., P. Jalali und M. Dabagh. „Computational Study of Pulstile Blood Flow in Aortic Arch: Effect of Blood Pressure“. In IFMBE Proceedings, 1198–201. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-642-03882-2_318.

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Svensson, Johan, Roland Gårdhagen, Einar Heiberg, Tino Ebbers, Dan Loyd, Toste Länne und Matts Karlsson. „Feasibility of Patient Specific Aortic Blood Flow CFD Simulation“. In Medical Image Computing and Computer-Assisted Intervention – MICCAI 2006, 257–63. Berlin, Heidelberg: Springer Berlin Heidelberg, 2006. http://dx.doi.org/10.1007/11866565_32.

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Muchada, R., und D. Cathignol. „Esophageal Measurement of Aortic Blood Flow by Echo-Doppler“. In Update in Intensive Care and Emergency Medicine, 356–65. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-642-83042-6_45.

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Šeta, Berin, Muris Torlak und Alija Vila. „Numerical Simulation of Blood Flow Through the Aortic Arch“. In IFMBE Proceedings, 259–68. Singapore: Springer Singapore, 2017. http://dx.doi.org/10.1007/978-981-10-4166-2_39.

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Gagaev, A. V., Anton L. Maximov, I. E. Soboleva, E. V. Chebotar, A. A. Charov, M. V. Riazanov und I. V. Gagaeva. „Effect of myocardial revascularization on the blood flow volume in carotid arteries“. In Cerebral Protection in Cerebrovascular and Aortic Surgery, 75–78. Heidelberg: Steinkopff, 1997. http://dx.doi.org/10.1007/978-3-642-95987-5_10.

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Chow, G., I. G. Roberts, P. Fallon, M. Onoe, A. Lloyd-Thomas, M. J. Elliott, A. D. Edwards und F. J. Kirkham. „The relation between arterial oxygen tension and cerebral blood flow during cardiopulmonary bypass“. In Cerebral Protection in Cerebrovascular and Aortic Surgery, 119–23. Heidelberg: Steinkopff, 1997. http://dx.doi.org/10.1007/978-3-642-95987-5_15.

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Konferenzberichte zum Thema "Aortic blood"

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Fukui, Tomohiro, und Koji Morinishi. „Influence of Sinus of Valsalva on Aortic Valve Movements by Lattice Boltzmann Method“. In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference. ASMEDC, 2011. http://dx.doi.org/10.1115/ajk2011-19021.

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Aortic valve is a membrane that plays an important role in controlling effective outputs of blood flow from the heart. Aortic stenosis is a disease that aortic valves barely open in systole, which cause considerable reduction of amount of blood flow. It is important to know aortic valve movements due to blood flow in order to consider mechanism of development of the aortic stenosis. In this study, we consider the influence of the sinus of Valsalva on aortic valve movements by Lattice Boltzmann method. The virtual flux method is applied to describe thin aortic valve leaflets. The shape of the sinus of Valsalva is approximated as a semi-ellipse. The aortic valve opens due to high pressure at the left ventricle side, and blood flows toward the aorta. The blood also flows into the sinus of Valsalva, and forms vortices. The aortic valve closure starts due to high pressure at the aorta side and vortices in the sinus of Valsalva as well. We successfully reproduced the aortic valve movements due to blood flows during cardiac cycle by means of virtual flux method.
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Amabili, Marco, Kostas Karazis, Rosaire Mongrain und Nastaran Shahmansouri. „A Model for the Nonlinear Buckling of Human Aorta“. In ASME 2012 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/imece2012-89141.

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Human aortas are subjected to large mechanical stresses due to blood flow pressurization and through contact with the surrounding tissue. It is essential that the aorta does not lose stability by buckling for its proper functioning to ensure proper blood flow. A refined reduced-order bifurcation analysis model is employed to examine the stability of an aortic segment subjected to internal blood flow. The structural model is based on a nonlinear cylindrical orthotropic laminated composite shell theory that assumes three aortic wall layers representing the tunica intima, media and adventitia. The fluid model contains the unsteady effects obtained from linear potential flow theory and the steady viscous effects obtained from the time-averaged Navier-Stokes equations. Residual stresses due to pressurization are evaluated and included in the model. The aortic segment loses stability by divergence with deformation of the cross-section at a critical flow velocity for a given static pressure, exhibiting a strong subcritical behaviour with partial or total collapse of the inner wall. Subsequent analyses including the effect of geometric wall imperfections indicate that imperfections in the axial direction have a more profound effect on the stability of the aorta decreasing the critical flow velocity for buckling.
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Kulp, Scott, Zhen Qian, Mani Vannan, Sarah Rinehart und Dimitris Metaxas. „Patient-specific aortic valve blood flow simulations“. In 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI 2014). IEEE, 2014. http://dx.doi.org/10.1109/isbi.2014.6868026.

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Wang, Jing, Suzie Brown und Stephen W. Tullis. „Oscillatory Blood Flow in a Deformable Human Aortic Arch“. In ASME 2011 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2011. http://dx.doi.org/10.1115/sbc2011-53676.

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The aorta is the largest artery in humans, stemming from the left ventricle of the heart and stretching down to the abdomen. It is responsible for distributing oxygenated blood to the rest of the body during each cardiac cycle. The pulsatile blood flow is complex in nature and has been previously modeled computationally in an effort to understand its effect on cardiovascular diseases and medical device design interaction [4,8–9]. However, the majority of these models either treat the vessel wall as rigid or have significantly simplified geometries, which from a physiological perspective are not true of large vessels such as the aorta. Here, the complex mechanical interaction between pulsatile blood flow and wall dynamics in the aortic arch is investigated using geometry adopted directly from CT images.
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Mori, Daisuke, Hao Liu und Takami Yamaguchi. „Effects of Distortion of the Aorta on the Blood Flow and Its Significance on the Localization of High Wall Shear Stress Region“. In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2538.

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Abstract The aorta is the largest artery in the body. It consists of the ascending aorta that leaves the left ventricle, the aortic arch where it curves about 180°, and the descending aorta. Three prominent branches to the head and upper limbs leave the aortic arch. In addition to this complex configuration, it was recently pointed out that the centerline of the aortic arch does not lie in a plane, and has a three dimensional (3D) distortion. This distortion induces very strong deviation of the 3D structure of the blood flow from that usually assumed to occur in flows in simple curved pipes (Caro et al. 1996). This 3D flow structure is thought to be responsible for some serious aortic diseases, including aortic aneurysms. It has been reported that the flow in a real human aorta is not the well-known twin vortex-type symmetrical secondary flow that is well established theoretically and experimentally for a simple curved pipe. Kilner et al. (1993) observed a single helical and retrograde secondary flow pattern by Magnetic Resonance Imaging (MRI).
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Minagawa, Tadanori, Yoshifumi Saijo, Sri Oktamuliani, Takafumi Kurokawa, Hiroyuki Nakajima, Kaoru Hasegawa, Takayuki Matsuoka et al. „Left Ventricular Blood Flow Dynamics In Aortic Stenosis Before And After Aortic Valve Replacement“. In 2018 40th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC). IEEE, 2018. http://dx.doi.org/10.1109/embc.2018.8512954.

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Bouaou, Kevin, Ioannis Bargiotas, Damian Craiem, Gilles Soulat, Thomas Dietenbeck, Sophia Houriez--Gombaud-Saintonge, Alain De Cesare et al. „Relative Aortic Blood Pressure Using 4D Flow MRI: Associations with Age and Aortic Tapering“. In 2017 Computing in Cardiology Conference. Computing in Cardiology, 2017. http://dx.doi.org/10.22489/cinc.2017.080-180.

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Wang, Jinfeng, Leren Tao, Yonghong Wang, Lihao Huang, Shuhong Zhang, Mengfang Liu, Jianqing Wu, Yongfu Li, Decheng Xi und Zhigao Zheng. „The Experimental Study on Cryofreeze-Drying of Porcine Aortic“. In ASME 2009 Second International Conference on Micro/Nanoscale Heat and Mass Transfer. ASMEDC, 2009. http://dx.doi.org/10.1115/mnhmt2009-18296.

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At present, the vascular tissue disease has become the major cause to against people’s health, vascular graft is an effective means for the treatment of vascular tissue disease, but the preservation of blood vessels has always been a big challenge. This paper based on the conduct of porcining aortic cryofreeze-drying, with using micro-CT to track the whole drying process, expect to reveal what vascular morphology changes have taken place during the process of cryofreeze-drying, and take a comparative analysis of porcine aortic mechanical properties between freeze-dried after the restoration of water and fresh porcine aortic by the Texture analyzer, so that uncover the effect the process of freeze-dried making on pig arteries mechanical properties. Test results showed that the pig aorta vascular occur stratification in the process of cryofreeze-drying, blood vessels freeze-dried following the resumption of water comparing the mechanical properties with the fresh blood vessels, its maximum axial tensile stress reduced by about 40%, and the largest peripheral tensile stress increase by about 45%, and the biggest puncture stress is about 75 percent of fresh blood vessels.
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Ghasemi, Zahra, Chang-Sei Kim, Eric Ginsberg, John Duell, Anuj Gupta und Jin-Oh Hahn. „Estimation of Central Aortic Blood Pressure From Non-Invasive Cuff Pressure Oscillation Signals via System Identification“. In ASME 2016 Dynamic Systems and Control Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/dscc2016-9785.

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This paper presents a model-based system identification approach to estimation of central aortic blood pressure waveform from non-invasive cuff pressure oscillation signals. First, we developed a mathematical model that can reproduce the relationship between central aortic blood pressure waveform and non-invasive cuff pressure oscillation signals at diametric locations by combining models to represent wave propagation in the artery, arterial pressure-volume relationship, and mechanics of the occlusive cuff. Second, we formulated the problem of estimating central aortic blood pressure waveform from non-invasive cuff pressure oscillation signals into a system identification problem. Third, we showed the proof-of-concept of the approach using simulated central aortic blood pressure waveform and cuff pressure oscillation signals. Finally, we illustrated the feasibility of the approach using central aortic blood pressure waveform and cuff pressure oscillation signals collected from a human subject. We showed that the proposed approach could estimate central aortic blood pressure waveform with accuracy: the root-mean-squared error associated with the central aortic blood pressure waveform was 1.7 mmHg (amounting to 1.6 % of the underlying mean blood pressure) while the errors associated with central aortic systolic and pulse pressures were −0.4 mmHg and −1.5 mmHg (amounting to −0.3 % and −1.4 % of the underlying mean blood pressure).
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Speelman, L., E. Moltzer, K. van der Heiden, P. van Heijningen, A. F. W. van der Steen, J. Essers, F. Gijsen und J. Wentzel. „Biomechanical Characteristics of Aortic Aneurysms Generated in Fibulin-4 Deficient Mice“. In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80590.

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Aortic aneurysms affect approximately 5% of the elderly population and aneurysm rupture is responsible for a significant number of deaths in the western world. Risk factors for aortic aneurysm include high cholesterol, high blood pressure, and smoking. Fibulin-4 is a glycoprotein, which is expressed in medial layers of blood vessels and a critical component for the structural integrity and elasticity of the aortic wall [1]. Mice with reduced levels of Fibulin-4 develop aortic abnormalities similar to Fibulin-4 patients, such as dilation of the ascending aorta. A 4-fold reduction of Fibulin-4 expression (fib-4R/R) causes a severe dilation, while a mice with a 2-fold reduction (fib-4+/R) show an onset of aneurysm formation, comparable with the development of an aneurysm in aging humans [2].
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Berichte der Organisationen zum Thema "Aortic blood"

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Fisher, Jay B., Richard C. Dennis, C. R. Valeri, Jonathan Woodson und Jeanne E. Doyle. Effect of Graft Material on Red Blood Cell Loss Following Aortic Surgery. Fort Belvoir, VA: Defense Technical Information Center, Juli 1990. http://dx.doi.org/10.21236/ada360187.

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