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Zeitschriftenartikel zum Thema "Anti-nuclear activists"

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Haines, Monamie Bhadra. „Contested credibility economies of nuclear power in India“. Social Studies of Science 49, Nr. 1 (Februar 2019): 29–51. http://dx.doi.org/10.1177/0306312719827114.

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STS scholars studying anti-nuclear activism in the context of nations in the Global North have observed the critical role of science to mediate relations of domination and resistance. Through a historical examination of anti-nuclear activism in India, this article investigates the instrumentalization of science as a liberal democratic rationality. In doing so, the article shows how elite Indian activists – many of whom are scientists, engineers, journalists and academic professionals – will never be seen as scientifically knowledgeable in nuclear matters, because of their non-state educational pedigrees. If activists cannot hold the state accountable through science, they have attempted to anticipate what other kinds of arguments and modes of contention may gain traction. As such, they have deployed more ‘guerilla’ tactics grounded in bureaucratic rationalities in the hopes of installing themselves as alternate sources of expertise in India’s nuclear landscape.
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Peterson, Christian Philip. „Changing the World from “Below”: U.S. Peace Activists and the Transnational Struggle for Peace and Détente in the 1980s“. Journal of Cold War Studies 22, Nr. 3 (August 2020): 180–224. http://dx.doi.org/10.1162/jcws_a_00926.

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Much more so than previous works in the field of U.S. foreign relations, this article explores the relationship between the Helsinki Accords and peace activism in the United States. The article explains how well-known groups such as U.S. Helsinki Watch and lesser-known ones such as Campaign for Peace and Democracy West/East used the Helsinki Final Act when they challenged U.S. peace activists to defend the rights of imprisoned anti-nuclear activists in the Soviet bloc and to link the causes of peace and human rights. The article also demonstrates how the exchanges between U.S. human rights and anti-nuclear activists fit into transnational debates about linkages between the issues of human rights, peace, détente, and the “Helsinki process.”
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van Troost, Dunya, Bert Klandermans und Jacquelien van Stekelenburg. „Friends in High Places“. Humanity & Society 42, Nr. 4 (07.10.2018): 455–79. http://dx.doi.org/10.1177/0160597618802537.

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Scholars working from the political opportunity approach have upheld the notion that the political context sets the grievances around which activist mobilizes. Inspired by Tarrow and colleagues plea to explain political activism by analyzing how activists are mobilized, this article focuses on the individual protester. The research question in this article reads how are activist’s protest emotions shaped by characteristics of the political context, specifically by their political alliances? We focus on the emotional constellation evoked by environmental issues (e.g., climate change and nuclear energy) with Green Parties as movement allies and anti-austerity issues with Social Democratic parties as movement allies. Specifically, the parliamentary position of these allies is linked to the relative stake anger and frustration have within the emotional constellation of demonstrators. Results are based on survey data collected among 6,598 demonstrators, and their emotions dispersed over 28 demonstrations in seven European countries. We conclude that having a politically well-connected friend seems to matter more to demonstrators’ emotional constellation than the ideological support provided by that friend.
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Laucht, Christoph. „‘Treatment Not Trident’: Medical Activism, Health Inequality and Anti-Militarism in 1980s Britain“. Social History of Medicine 32, Nr. 4 (19.04.2018): 843–66. http://dx.doi.org/10.1093/shm/hky027.

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Summary In 1985, Britain’s chief group of medical anti-nuclear weapons activists, the Medical Campaign Against Nuclear Weapons (MCANW), launched its ‘Treatment, Not Trident’ (TNT) campaign. TNT called on the Thatcher Government to cancel the acquisition of the Trident nuclear weapon system and divert those funds to the National Health Service and foreign aid instead. Using TNT, this article makes some more general observations about key aspects of the history, nature and ideologies of medical activism in relation to anti-militarism and health inequality. Alongside a conceptualisation of ‘medical activism’, it offers an examination of chief ways in which the strategic mobilisation of health and welfare priorities, and a growing interest in developing nations enabled MCANW to reach a larger audience. Moreover, higher levels of professionalisation, politicisation and inclusivity contributed to TNT’s success, making it a crucial moment in the development of both MCANW and medical activism in general.
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Teimouri, Amirhossein. „Google Plus as a Contentious Field of Revolutionary Identity“. Comparative Sociology 20, Nr. 3 (04.08.2021): 402–16. http://dx.doi.org/10.1163/15691330-bja10036.

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Abstract Social media platforms have been increasingly reinvigorating extreme movements, especially rightist movements. Utilizing unique Google Plus data, the author shows the rise and fall of the 2015 rightist anti-Nuclear Deal movement in Iran. He argues that the Google Plus platform in 2015 provided the new generation of revolutionary Islamist rightist activists with a contentious space of mobilization, enabling them to develop a new revolutionary rightist identity. This revolutionary identity and its corresponding language and discourse did not fully unfold in Iranian mainstream rightist media, even though rightist groups, compared to liberal groups, are not censored and repressed. The new generation of rightist activists perceived the Nuclear Deal as an existential threat to revolutionary principles of the country, and thus played out their outrage and identity anxieties on Google Plus. The author contends that this online outrage, due to the activists’ identity bond with the regime and the 1979 Iranian Revolution, however, did not translate into any massive offline mobilization against the Nuclear Deal. He also discusses the methodological implications of using social media data, especially the discontinuation of Google Plus.
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HO, Ming-Sho. „The Politics of Anti-Nuclear Protest in Taiwan: A Case of Party-Dependent Movement (1980–2000)“. Modern Asian Studies 37, Nr. 3 (25.06.2003): 683–708. http://dx.doi.org/10.1017/s0026749x03003068.

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This essay tries to understand a particular pattern of the relation between social movement and political party. By analyzing the development of the anti-nuclear protest in Taiwan, the author puts forth the concept of party-dependent movement. This term denotes an awkward situation where the fate of a social movement is bound to the electoral performance of a certain political party. In Taiwan, the rise of anti-nuclear voice is closely related to the democratic opening. The Democratic Progressive Party (DPP) adopted an unequivocal anti-nuclear stand ever since its founding in 1986, thus helped to collect the increasing support from the broad movement constituents. But the growing DPP has other political priorities, which means the anti-nuclear goal is often shelved to the disappointment of movement activists. As a consequence of the early convergence, the movement has not been able to re-assert its autonomy.
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Branagan, Marty. „The Australian Movement against Uranium Mining: Its Rationale and Evolution“. International Journal of Rural Law and Policy, Nr. 1 (09.09.2014): 1–12. http://dx.doi.org/10.5130/ijrlp.i1.2014.3852.

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This paper begins with a brief historical overview of the Australian movement against uranium mining, before focussing on two major campaigns: Roxby and Jabiluka. It describes the reasons the activists gave at the time for their blockades of the Roxby Downs uranium mine in South Australia in 1983 and 1984. These reasons – such as perceptions that the industry is unsafe - have changed little over time and were the basis for the campaign against the proposed Jabiluka mine in the Northern Territory in 1998. They continue to be cited by environmental groups and Aboriginal Traditional Owners to this day as new situations arise, such as the 2011 Fukushima Daiichi nuclear accident.The paper then describes how the movement evolved between the Roxby and Jabiluka blockades, with changes to the movement’s philosophy, strategy, tactics and internal dynamics. This analysis includes a comparison between two anti-nuclear bike rides, one a year after the 1984 Roxby blockade and involving some of the same activists, and another at the time of the Jabiluka blockade. This author was present at all these events, and provides an emic (insider) perspective within a longitudinal participant-observation methodology. Although this perspective obviously has a subjective element, the paper fills a gap in that there is little written history of these blockades (particularly Roxby) and more generally of Australian resistance to uranium mining, let alone the aspects of nonviolence and movement evolution. It is an introductory history of these campaigns, examining the direct action components, the practicalities of nonviolent campaigning, and the evolution of Australian anti-uranium activism.
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SINGER, ERIC S. „Civil defence in the city: federal policy meets local resistance in Baltimore, 1957–1964“. Urban History 42, Nr. 4 (23.09.2015): 547–63. http://dx.doi.org/10.1017/s0963926815000553.

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ABSTRACT:Between 1950 and 1964, as a result of slight federal policy shifts, Cold War civil defence went from a pro-urban policy dedicated to the preservation of communities to an anti-urban policy focused on social control in the wake of an attack. Civil defence volunteers in Baltimore along with some of the city's civil defence paid staff, who had bought the federal message that they could protect themselves and their communities for nuclear war, allied with anti-nuclear activists against an increasingly militarized programme – one that by 1961 prioritized post-attack policing and de-emphasized the imperative to preserve urban neighbourhoods.
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Brown, Antje. „The Dynamics of Frame-bridging: Exploring the Nuclear Discourse in Scotland“. Scottish Affairs 26, Nr. 2 (Mai 2017): 194–211. http://dx.doi.org/10.3366/scot.2017.0178.

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Simple indicative factors such as political populism and resource abundance cannot fully explain the Scottish Government's anti-nuclear energy policy. To grasp the current policy stance, it is necessary to pay attention to the wider contextualisation of policy framing and specifically the dynamic of story-telling and frame-bridging that ultimately feeds into governmental policy. The Scottish Government's decisive ‘no’ to a new nuclear fleet can be better understood by considering the underlying (and deliberate) bridging of policy frames that is noticeable between environmental, pacifist, and Scottish independence actors. This bridging not only affects the individual sets of story-telling but also develops a dynamic that reinforces individual stories and transcends well beyond the groups' original remit and objectives. With the help of policy framing analysis, research interviews and documentary analysis, the article explores the dynamic connections between anti-nuclear and independence activists and their causes in Scotland. The article highlights their triangular bridges in terms of personnel, language and story-telling and argues that these are instrumental in shaping the Scottish Government's anti-nuclear energy policy.
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Moore, Clive. „Greg Weir“. Queensland Review 14, Nr. 2 (Juli 2007): 56. http://dx.doi.org/10.1017/s1321816600006620.

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How do political activists begin? What is their motivation? For quiet Greg Weir, just graduated as a trainee school teacher from Kelvin Grove College of Advanced Education in 1976, it was being refused employment by the Queensland government because he was a spokesperson for a gay student support group. Minister for Education Val Bird said in Parliament that ‘student teachers who participated in homosexual and lesbian groups should not assume they would be employed by the Education Department on graduation’. With his future as a teacher destroyed, Greg became one of Queensland's best-known political activists. His cause was taken up by the Australian Union of Students and he became a catalyst in developing awareness of gay and lesbian issues all over Australia. Greg was then employed as a staff member in the office of Senator George Georges and later Senator Bryant Burns, and became a Labor Party activist, influential in the peace, anti-nuclear, education and civil liberties movements in the 1970s and 1980s. He also helped set up HIV/AIDS awareness groups in the 1980s, and went on to become one of the central organisers of the campaign for gay law reform in 1989–90, which culminated in the decriminalisation of male homosexuality in 1990. In 1991 Greg was involved in campaigns to include homosexuality as a category in new antidiscrimination legislation.
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Dissertationen zum Thema "Anti-nuclear activists"

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Ogley-Oliver, Emma JF. „Development of Activism: The Elders of the Anti-nuclear Movement“. Digital Archive @ GSU, 2012. http://digitalarchive.gsu.edu/psych_diss/104.

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The US anti-nuclear movement formed in opposition to the development of nuclear weapons and energy. Anti-nuclear activists have rallied since the late 1970’s opposed to the construction of Plant Vogtle near Waynesboro, Georgia due to the social and environmental justice issues related to the nuclear industry. In 2010, the nuclear industry proposed a nuclear resurgence in the US, proposing to construct new reactors at Plant Vogtle. This represented the first time new nuclear reactors had been proposed since the moratorium on new reactors as a result of the partial meltdown at Three Mile Island in 1979. The aim of the study is to understand the experience of “first wave” anti-nuclear activists in Georgia (those engaged for twenty years or more). Bronfenbrenner’s Ecological Framework was employed to locate anti-nuclear activists’ perceived facilitators and barriers to their activism. Semi-structured interviews with these activists yielded rich descriptions about their experience in the anti-nuclear movement. Activists endorsed facilitators and barriers related to individual characteristics however, the majority of activists perceived facilitators and barriers beyond the individual level. Specifically, the majority of activists mentioned facilitators and barriers relating to the media and political systems and the power and resource imbalances within society. The role of community psychology is discussed in relation to this field of inquiry.
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Dillehay, McKillip Kelsey L. „Anti-cancer implications of small molecule compounds targeting proliferating cell nuclear antigen“. University of Cincinnati / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1413820048.

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Williams, James Michael. „Assessment of anti-neoplastic activity in cancerous and non-cancerous cells using nuclear growth indicators“. CSUSB ScholarWorks, 1997. https://scholarworks.lib.csusb.edu/etd-project/1321.

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Still, Patrick C. „Cytotoxic Alkaloids from Microcos paniculata with Activity at Neuronal Nicotinic Receptors“. The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1365688930.

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Nascimento, Mar?lia da Silva. „Avalia??o das propriedades farmacol?gicas de polissacar?deos do fungo Scleroderma nitidum“. Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/12551.

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Made available in DSpace on 2014-12-17T14:03:31Z (GMT). No. of bitstreams: 1 MariliaSN.pdf: 1926704 bytes, checksum: da3259de4a29785c64e3b5736af19e2f (MD5) Previous issue date: 2010-02-23
Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior
Several pharmacological properties have been attributed to isolated compounds from mushroom. Recently, have these compounds, especially the polysaccharides derived from mushrooms, modulate the immune system, and its antitumor, antiviral, antibiotic and antiinflammatory activities. This study assesses the possible pharmacological properties of the polysaccharides from Scleroderma nitidum mushroom. The centesimal composition of the tissue showed that this fungus is composed mainly of fibers (35.61%), ash (33.69%) and carbohydrates (25.31%). The chemical analysis of the polysaccharide fraction showed high levels of carbohydrates (94.71%) and low content of protein (5.29%). These polysaccharides are composed of glucose, galactose, mannose and fucose in the following molar ratios 0.156, 0.044, 0.025, 0.066 and the infrared analysis showed a possible polysaccharide-protein complex. The polysaccharides from Scleroderma nitidum showed antioxidant potential with concentration-dependent antioxidant activity compared to ascorbic acid. The analysis scavenging of superoxide radical and inhibition of lipid peroxidation showed that the polysaccharides from S. nitidum have an IC50 of 12.70 mg/ml and EC50 10.4 μg/ml, respectively. The antioxidant activity was confirmed by the presence of reducing potential of these polysaccharides. The effect of these polymers on the inflammatory process was tested using the carrageenan or histamine-induced paw edema model and the sodium thioglycolate or zymosan-induced model. The polysaccharides were effective in reducing edema (73% at 50 mg/kg) and cell infiltrate (37% at 10 mg/kg) in both inflammation models tested. Nitric oxide, a mediator in the inflammatory process, showed a reduction of around 26% at 10 mg/kg of body weight. Analysis of pro- and anti-inflammatory cytokines showed that in the groups treated with polysaccharides from S. nitidum there was an increase in cytokines such as IL-1ra, IL-10, and MIP-1β concomitant with the decrease in INF-γ (75%) and IL-2 (22%). We observed the influence of polysaccharides on the modulation of the expression of nuclear factor κB. Thus, polysaccharides from S. nitidum reduced the expression of NF-κB by up to 64%. The results obtained suggest that NF-κB modulation is one of the possible mechanisms that explain the anti-inflammatory effect of polysaccharides from the fungus S. nitidum.
Diversas propriedades farmacol?gicas t?m sido atribu?das aos compostos isolados de fungos. Recentemente, t?m-se referido quanto ? capacidade desses compostos, principalmente os polissacar?deos derivados de cogumelos, de modular o sistema imunol?gico, al?m de suas a??es antitumoral, antiviral, antibi?tica e antiinflamat?ria. Este estudo avalia a capacidade dos polissacar?deos do fungo Scleroderma nitidum quanto ?s suas poss?veis propriedades farmacol?gicas. A composi??o centesimal do tecido deste fungo demonstrou que este ? composto principalmente por fibras (35,61%), cinzas (33,69%) e carboidratos (25,31%). As an?lises qu?micas da fra??o polissacar?dica revelaram alto teor de carboidratos (94,71%) e baixo teor de prote?nas (5,29%). Esses polissacar?deos s?o constitu?dos por glicose, galactose, manose e fucose nas seguintes propor??es molares 0,156; 0,044; 0,025; 0,066, respectivamente e a an?lise de infravermelho demonstrou um poss?vel complexo polissacar?deo-prote?na. Os polissacar?deos de S. nitidum demonstraram potencial antioxidante com atividade relativa ao ?cido asc?rbico massa-dependente. As an?lises sobre a varredura de radicais super?xido e inibi??o da peroxida??o lip?dica demonstraram que os polissacar?deos de S. nitidum apresentam um IC50 estimado em 12,70 mg/ml e EC50 10,4 μg/ml, respectivamente. A atividade antioxidante foi confirmada pela presen?a de potencial redutor dos polissacar?deos. Este estudo tamb?m avaliou a capacidade dos polissacar?deos do fungo S. nitidum como agente antiinflamat?rio. O efeito destes pol?meros no processo inflamat?rio foi testado usando-se os modelos de edema de pata induzido por carragenana ou histamina e o modelo de peritonite induzida por tioglicolato de s?dio ou zymosan. Os polissacar?deos foram efetivos na redu??o do edema (73% a 50 mg/kg) e infiltrado celular (37% a 10 mg/kg) nos dois modelos de inflama??o testados. ?xido n?trico, um mediador do processo inflamat?rio, mostrou uma redu??o de cerca de 26% nos grupos tratados com a dose 10 mg/kg dos polissacar?deos. A an?lise de citocinas pr? e antiinflamat?rias mostrou que nos grupos tratados com os polissacar?deos de S. nitidum houve aumento de citocinas como IL-1ra (2x), IL-10 (3x) e concomitante a diminui??o de INF-γ (75%), MIP-1β (29%) e IL-2 (22%). Al?m disso, nos grupos tratados com os polissacar?deos tamb?m foi verificada uma inibi??o de cerca de 64% na express?o do NF-κB. Os resultados obtidos sugerem que a modula??o do NF-κB ? um dos poss?veis mecanismos que esclarece os efeitos anti-inflamat?rios dos polissacar?deos do fungo S. nitidum.
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Hanes, Leah. „Leadership for Social Change: Illuminating the Life of Dr. Helen Caldicott“. Antioch University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=antioch1432298324.

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Elie, Margaux. „Développement de nouveaux complexes organométalliques de métaux de transition polyvalents pour la scintillation et la chimie médicinale“. Thesis, Normandie, 2017. http://www.theses.fr/2017NORMC227.

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Deux nouvelles familles de complexes de cuivre(I) cationiques, de formules [Cu(NHC)(N^N)][X] et [Cu(P^P)(N^N)][PF6], ont été synthétisées avec des ligands 2,2’ bis pyridyl pontés, chélates à six chaînons, facilement modulables. Ces complexes présentent des émissions à l’état solide centrées entre 455 et 520 nm (bleu à vert), avec de larges décalages de Stokes et des rendements quantiques pouvant atteindre 0,86. De plus, l’émission via un phénomène de fluorescence retardée activée thermiquement (TADF) a été prouvée pour les complexes [Cu(NHC)(N^N)][X]. Les premiers scintillateurs plastiques dopés avec des complexes de cuivre(I) détectant les radiations nucléaires de type gammas ont été obtenus avec des complexes de formule générale [Cu(P^P)(N^N)][PF6]. Les complexes de formule [Cu(NHC)(N^N)][X] ont permis l’obtention des premières Cellules Electrochimiques Luminescentes (LECs) émettant dans le bleu et incorporant des complexes de cuivre(I). Enfin, les complexes de formule [Cu(NHC)(N^N)][X] à ligand 2,2’ dipyridylamine présentent une activité cytotoxique envers différentes lignées de cellules cancéreuses et apportent la possibilité d’une action ciblée sur les cellules tumorales via l’ajout d’un vecteur. La polyvalence de ces complexes de cuivre(I) repose sur les ligands 2,2’-bis-pyridyl pontés, chélates à six chaînons, dont la synthèse est facile d’accès et les propriétés électroniques et structurales sont modulables
New cationic copper(I) complexes of general formula [Cu(NHC)(N^N)][X] and [Cu(P^P)(N^N)][PF6] were developed with 6-membered-ring 2,2’-bis-pyridyl derivatives as ligand. These complexes exhibited blue (420 nm) to green (520 nm) emissions in solid state, with large Stokes shifts and photoluminescence quantum yields up to 0.86. Furthermore, the emission of the [Cu(NHC)(N^N)][X] complexes via a thermally activated delayed fluorescence (TADF) was demonstrated. The first plastic scintillators incorporating copper(I) complexes and detecting gamma radiations were obtained with [Cu(P^P)(N^N)][PF6] complexes. Application of the [Cu(NHC)(N^N)][X] complexes to the LEC technology led to the first copper(I)-based blue emitting device. In the last chapter, we also demonstrated that copper(I) complexes [Cu(NHC)(N^N)][X] bearing a 2,2’-dipyridylamine as N^N ligand exhibited high cytotoxycity against different cancer cells lines. These complexes paved the way for the design of a new type of copper(I) anti-cancer agents with the opportunity to increase the selectivity against cancer cells via a vectorization of the N^N ligand. The versatility of these copper(I) complexes demonstrated in this work relied on the easy to handle and highly modular 2,2’-bis-pyridyl ligands
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Risimati, Risimati Elia. „Forging resistance: An analysis of opposition to nuclear energy in South Africa“. Thesis, 2018. https://hdl.handle.net/10539/31340.

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Research report submitted in partial fulfilment of the requirements Of the Master of Arts Degree In Sociology At the University of Witwatersrand Department of sociology
The main purpose of this research is to provide an analysis of opposition to nuclear energy in South Africa, focusing on organisations and activists opposed to the current nuclear build programme. The organisations opposed to nuclear include Earthlife Africa, Greenpeace, Coalition Against nuclear Energy, national Union of Mineworkers, the Economic Freedom fighters and Democratic Alliance, COSATU and other organisations. The study utilises a qualitative approach, mainly document analysis complimented by indepth expert interviews. The South African nuclear energy programme is a polarised issue triggering intense and often emotive debate on both sides, anti-nuclear activists and pronuclear proponents. The research pays specific attention to anti-nuclear activists and organisations opposed to South Africa's nuclear energy programme. In order to understand the anti-nuclear position, I have also incorporated pro-nuclear arguments in the study to have a better grasp of the concerns raised by organisations opposing nuclear energy. There are three main points of conflict: economic, environmental, and political. I show how opponents have framed resistance around cost and safety concerns, environmental impacts associated with nuclear and the nexus of elite political capture of state resources.
Andrew Chakane 2021
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SHEN, CHIH-LUNG, und 沈志隆. „Ribosome Protein L4 is essential for Epstein–Barr Virus Nuclear Antigen 1 function and GAP31 from an ancient medicinal plant exhibits anti-viral activity through targeting to Epstein-Barr virus nuclear antigen 1“. Thesis, 2019. http://ndltd.ncl.edu.tw/handle/x8ddaz.

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博士
慈濟大學
醫學科學研究所
107
Epstein-Barr virus (EBV), a world-wide oncogenic γ-human herpesvirus, is highly associated with several types of malignancies. EBV establishes permanent infection in B lymphocytes, which is characterized by expression of latency-associated nuclear antigens (EBNA), integral membrane proteins (LMPs), and non-coding RNAs. EBNA1 is the only latent gene to be prevalently expressed in almost all EBV+ neoplasms, and dimeric EBNA1-mediated origin of plasmid replication (oriP) DNA episome maintenance is essential for EBV-mediated tumorigenesis. Our first study aimed to determine Ribosome Protein L4 (RPL4) is essential for EBNA1 function. In this study, we found that EBNA1 binds to Ribosome Protein L4 (RPL4). RPL4 shRNA knockdown decreased EBNA1 activation of an oriP luciferase reporter, EBNA1 DNA binding in lymphoblastoid cell lines, and EBV genome number per lymphoblastoid cell line. EBV infection increased RPL4 expression and redistributed RPL4 to cell nuclei. RPL4 and Nucleolin (NCL) were a scaffold for an EBNA1-induced oriP complex. The RPL4 N terminus cooperated with NCL-K429 to support EBNA1 and oriP mediated episome binding and maintenance, whereas the RPL4 C-terminal K380 and K393 induced oriP DNA H3K4me2 modification and promoted EBNA1 activation of oriP-dependent transcription. These observations provide new insights into the mechanisms by which EBV uses NCL and RPL4 to establish persistent B-lymphoblastoid cell infection. The next study demonstrated that GAP31 from an ancient medicinal plant exhibits anti-viral activity through targeting to EBNA1. Herein, we identify the EBNA1 DNA-binding domain as a core for GAP31 binding by performing affinity pulldown assays. Recombinant GAP31 (rGAP31) was shown to impair EBNA1-induced dimerization; consequently, it abrogated both EBNA1/oriP-mediated binding and transcription. Importantly, the therapeutic effects of GAP31 showed its capability to abrogate EBV-driven cell transformation and proliferation, and EBV-dependent tumorigenesis in xenograft animal models. Notably, the EBNA1 binding-mutant rGAP31 R166A/R169A simply exhibits defective phenotypes in the above-mentioned studies. Our data suggest rGAP31 is a potential anti-viral drug which can be applied to the development of therapeutic strategies against EBV-related malignancies.
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Bücher zum Thema "Anti-nuclear activists"

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Harvey, Kyle. American Anti-Nuclear Activism, 1975–1990. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841.

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1930-2005, Ehrler Klaus, Hrsg. Der Wettlauf zum Frieden: Klaus Ehrler in Texten und Kontexten. Bonn: Pahl-Rugenstein, 2007.

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Ehrler, Ingrid. Der Wettlauf zum Frieden: Klaus Ehrler in Texten und Kontexten. Bonn: Pahl-Rugenstein, 2007.

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Eco-nationalism: Anti-nuclear activism and national identity in Russia, Lithuania, and Ukraine. Durham: Duke University Press, 1996.

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Kaur, Raminder. Kudankulam. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780199498710.001.0001.

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The book tells the many stories that circulate around a nuclear power plant in Kudankulam in the southern peninsular region of Tamil Nadu in India from the late 1980s. The tales are by way of fishermen and women, farmers, environmentalists, activists, writers, scholars, teachers, journalists, priests, children, as much as they are of lawyers, scientists, state officials and the author drawing upon an interdisciplinary field as the subject compels. They show how peninsular residents contended with the prospect of one of Asia’s largest nuclear enterprise being built on their doorstep. They reveal what role the nuclear plant plays in contested discourses of development, democracy, and nationalism in multiple spaces of criticality. Based on over a decade of historical and ethnographic research, we learn about the anti-nuclear campaign’s part in ‘right-to-lives’ movements, the (re)production of knowledge and ignorance in the understanding of radiation, and tactics to create an evidence base in response to the otherwise unavailable or inaccessible data on radiation and public health in India. In the process, the author casts a lens on how national and transnational solidarity was both received and curtailed, where processes of neo-liberalization and national security led to the hardening of the ‘nuclear state’. This phenomenon came with the direct and indirect repression of the anti-nuclear movement with the engineering of ‘death conditions’ for its protagonists. Altogether, this is one of the few books that has at its heart the many facets of a grassroots movement for energy justice in the global south from the 1980s that, three decades on, went on to become an international cause célèbre.
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Harvey, K. American Anti-Nuclear Activism, 1975-1990: The Challenge of Peace. Palgrave Macmillan, 2014.

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American Anti-Nuclear Activism, 1975-1990: The Challenge of Peace. Palgrave Macmillan, 2014.

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8

Hintz, Lisel. Taking the Theory “Outside”. Oxford University Press, 2018. http://dx.doi.org/10.1093/oso/9780190655976.003.0007.

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This chapter shows how identity contestation theory extends to state and non-state actors outside of Turkey, aiding understanding of how identity struggles spill over into foreign policy. It focuses on (1) the Israeli Likud Party’s efforts to shore up hardline, anti-Iran support in the US Congress; (2) India’s foreign policy shifts under the Hindu nationalist BJP; (3) Iranian moderates’ use of the nuclear deal as Western engagement to advance their position back home; and (4) anti-apartheid activists’ normative suasion tactics to force the United States to discontinue support of South Africa’s apartheid regime. The chapter demonstrates how these groups can also use foreign policy as an arena via institutions, diaspora groups, and transnational civil society to circumvent identity-based obstacles back home. These cases include the ongoing diplomacy of Turkey’s Kurdish movement with EU institutions and the Gülen movement’s efforts to spread Turkish Calvinism through its vast institutional network abroad.
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Fox-Cardamone, D. Lee. The experimental precursors of anti-nuclear activism: Attitudes, subjective norms and efficacy. 1990.

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Dawson, Jane I. Eco-Nationalism: Anti-Nuclear Activism and National Identity in Russia, Lithuania, and Ukraine. Duke University Press, 1996.

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Buchteile zum Thema "Anti-nuclear activists"

1

Harvey, Kyle. „Introduction: Dynamics of Anti-Nuclear Activism in the Second Cold War“. In American Anti-Nuclear Activism, 1975–1990, 1–11. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_1.

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Harvey, Kyle. „Anti-Nuclear Coalitions: Pacifism, Radical Action, and a Rising Atomic Threat“. In American Anti-Nuclear Activism, 1975–1990, 12–41. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_2.

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Harvey, Kyle. „Building a Mainstream Movement: Advertising, Publicity, and Image“. In American Anti-Nuclear Activism, 1975–1990, 42–67. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_3.

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Harvey, Kyle. „Personal Politics: Radical Feminism, Difference, and Anti-Nuclear Activism“. In American Anti-Nuclear Activism, 1975–1990, 68–92. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_4.

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Harvey, Kyle. „Prayer or Protest? Fasting, Nonviolence, and Anti-Nuclear Activism in the 1980s“. In American Anti-Nuclear Activism, 1975–1990, 93–116. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_5.

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Harvey, Kyle. „Activism in the Heartland: Local Identities, Community, and The Day After in Lawrence, Kansas“. In American Anti-Nuclear Activism, 1975–1990, 117–42. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_6.

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Harvey, Kyle. „Lifestyle Politics and Participatory Democracy: Communicating Peace across the United States on the Great Peace March“. In American Anti-Nuclear Activism, 1975–1990, 143–67. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_7.

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Harvey, Kyle. „Epilogue“. In American Anti-Nuclear Activism, 1975–1990, 168–69. London: Palgrave Macmillan UK, 2014. http://dx.doi.org/10.1057/9781137432841_8.

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Hobson, Emily K. „Money for AIDS, Not War“. In Lavender and Red. University of California Press, 2016. http://dx.doi.org/10.1525/california/9780520279056.003.0007.

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Although AIDS direct action is generally described as beginning with ACT UP, it first developed as activists drew tactics and ideas from Central American solidarity and the anti-nuclear movement. Anti-militarism catalyzed AIDS direct action in the Bay Area; its influences appeared in 1984, took on force in 1986, and by 1987 shaped national networks of AIDS activism. The groups Citizens for Medical Justice and the AIDS Action Pledge paved the way for the formation of ACT UP/San Francisco and Stop AIDS Now Or Else. AIDS direct action stood as the culmination of the gay and lesbian left even as it marked the start of a new queer politics. However, these radical genealogies were obscured with the deaths of many activists.
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Kaur, Raminder. „The World of the In/visibles“. In Kudankulam, 116–42. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780199498710.003.0004.

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As we explore the anti-Kudankulam movement, we do not confine our focus solely to the most visible manifestations of anti-nuclear resistance even though this remains important. Chapter 4 therefore takes the focus to discourses of risk, radiation, and the (re)production of knowledge and ignorance as a necessary prologue to nuclear developments. While activists presented radioactivity as a pathological life invader, nuclear authorities channelled it through five somewhat contradictory registers: first, to do with denial and dismissal of any dangers; second, to do with domestication or normalization when it is held to be present everywhere on the planet; third, with respect to the high levels of technical manageability; fourth, in view of radioactivity’s many virtues in modern life; and fifth, aggrandizing it so as that ionizing radiation is actually ‘good’. We then consider how this radiation regime compared with views circulating around nuclear employees and the controversy over safe radiation levels.
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Konferenzberichte zum Thema "Anti-nuclear activists"

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Yuan, Jun, Ji-Hong Yao, Qin Zhou, Xiao-Wei Hu, Liang Chu und Xiao-Feng Tian. „Anti-inflammatory Activity of Salvianic acid A through the Inhibition of Nuclear Factor-kappaB Activation in Peritoneal Macrophage“. In 2009 3rd International Conference on Bioinformatics and Biomedical Engineering (iCBBE). IEEE, 2009. http://dx.doi.org/10.1109/icbbe.2009.5162374.

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Jang, Ik Soon, Junsoo Park, Seung Hoon Lee und JongSoon Choi. „Abstract LB-9: Mountain ginseng extract exhibits anti-lung cancer activity by inhibiting the nuclear translocation of NF-κB.“ In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-lb-9.

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Landesman, Yosef, Trinayan Kashyap, Boris Klebanov, Sivan Elloul, Marsha Crochiere, Sharon Friedlander, William Senapedis, Robert Carlson, Michael Kauffman und Sharon Shacham. „Abstract 2074: Selective inhibitor of nuclear export (SINE) compounds show synergistic anti-tumor activity in combination with dexamethasone in multiple myeloma“. In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-2074.

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Catlow, Fred. „Experience in Choices for Decommissioning the Dounreay Site“. In ASME 2009 12th International Conference on Environmental Remediation and Radioactive Waste Management. ASMEDC, 2009. http://dx.doi.org/10.1115/icem2009-16183.

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The paper describes the public participation from the viewpoint of a stakeholder and member of the public. The dialogue between various members of the Dounreay Stakeholders Committee vary widely and do not always seem to represent the views of the wider public. Whilst great care has been taken to select various options for the ultimate condition of the Dounreay site and these have been discussed at great length and the preferred option selected by consensus, there still appears to be some conflict within the local community. It is probable that if the local population had to vote on the options for the future of the Dounreay nuclear site the outcome would be vastly different from that of the Stakeholders Committee. Whilst the politicians have been elected by the people, they represent a distinctly anti-nuclear view (even to the extent of decommissioning) whereas many local people (especially the workers on the Dounreay site) would prefer to see a continuation of nuclear activity at Dounreay. The problem is not only with local politicians but at national level in Scotland itself where the Scottish National Party has formed a coalition with the Green Party on condition all nuclear activities are phased out.
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Choay, J., M. Petitou, B. Perly, B. Casu, M. Ragazzi und D. Ferro. „MOLECULAR CONFORMATION OF THE PENTASACCHARIDE CORRESPONDING TO THE BINDING SITE OF HEPARIN TO ANTITHROMBIN III“. In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1642828.

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The knowledge of the tridimensional structure of the sequence required in heparin for binding to anti thrombin III (AT) is essential for the understanding of the molecular basis of the anticoagulant and antithrombotic activity of this glycosamino-glycan. This problem was approached by a combined experimental (chemical synthesis and Nuclear Magnetic Resonance, "NMR") and theoretical (force field calculations) study of the pentasaccharide I reproducing the minimal sequence for high affinity binding to AT.NMR data (interproton coupling constants and nuclear-Over-hauser-enhancement) were used to test a number of possible conformation of I proposed on the basis of-molecular energy calculation. In particular, these studies, confirming the results obtained by force field calculations, showed that the sulfated iduronic residue (Is) conformation is an equilibrium between the chair 4C4 and the skew boat2S0, and permitted to discard models with the Is residue in the alternate chair 4C1. It is of interest that the relative population of the 4C4 and 2S0 conformers of IS in sequence I (40:60) is reversed with respect to that found for the same residue in the regular sequences of heparin (60:40), such a reversal being largely associated with electrostatic interactions caused by the unique 3-0-sulfo group ot the preceding amino sugar residue. The most favoured models of I are characterized by a cluster of anionic groups including all the sulfate groups proposed as essential for full expression of the activity (full line square on the formula) but one (dotted line square on the formula), plus the carboxylate group of the glucuronic acid residue.
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Elloul, Sivan, Hua Chang, Boris Klebanov, Trinayan Kashyap, Maxwell Werman, Margaret Lee, Yosef Landesman, Sharon Shacham, Michael Kauffman und Sharon Y. Friedlander. „Abstract 2219: Selinexor, a selective inhibitor of nuclear export (SINE) compound, shows synergistic anti-tumor activity when combined with PD-1 blockade in a mouse model of colon cancer“. In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2219.

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Argueta, Christian, Boris Klebanov, Trinayan Kashyap, Hua Chang, Sharon Friedlander, Erkan Baloglu, Margaret Lee, Humphrey Gardner, Sharon Shacham und William Senapedis. „Abstract 1587: Disruption of nuclear export with selinexor or KPT-8602 reduces androgen receptor expression and leads to potent anti-tumor activity in preclinical models of androgen-independent prostate cancer“. In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-1587.

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Elloul, Sivan, Hua Chang, Boris Klebanov, Trinayan Kashyap, Maxwell Werman, Margaret Lee, Yosef Landesman, Sharon Shacham, Michael Kauffman und Sharon Y. Friedlander. „Abstract 1299: Selinexor, a selective inhibitor of nuclear export (SINE) compound shows enhanced anti-tumor activity when combined with either venetoclax or bendamustine in diffuse large B cell lymphoma (DLBCL) mouse models“. In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-1299.

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