Auswahl der wissenschaftlichen Literatur zum Thema „Anti-MRSA activity“
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Zeitschriftenartikel zum Thema "Anti-MRSA activity":
Asnani, Ari, Eva Luviriani und Oedjijono Oedjijono. „Activity of Actinomycetes Isolated from Mangrove Segara Anakan Cilacap toward Methicillin-resistant Staphylococcus aureus (MRSA)“. Jurnal Kimia Sains dan Aplikasi 23, Nr. 1 (06.12.2019): 1–7. http://dx.doi.org/10.14710/jksa.23.1.1-7.
Kubo, Isao, Ping Xiao und Ken'ichi Fujita. „Anti-MRSA activity of alkyl gallates“. Bioorganic & Medicinal Chemistry Letters 12, Nr. 2 (Januar 2002): 113–16. http://dx.doi.org/10.1016/s0960-894x(01)00663-1.
Yao, Cheng-Jiao, Yi-lin Li, Meng-Jun Pu, Li-Hong Luo, Qin Xiong, Feng-Jiao Xie, Ting-Lin Li und Pei-Min Feng. „Aminoglycosides with Anti-MRSA Activity: A Concise Review“. Current Topics in Medicinal Chemistry 21, Nr. 27 (08.12.2021): 2483–99. http://dx.doi.org/10.2174/1568026621666211004093647.
Yao, Cheng-Jiao, Yi-lin Li, Meng-Jun Pu, Li-Hong Luo, Qin Xiong, Feng-Jiao Xie, Ting-Lin Li und Pei-Min Feng. „Aminoglycosides with Anti-MRSA Activity: A Concise Review“. Current Topics in Medicinal Chemistry 21, Nr. 27 (08.12.2021): 2483–99. http://dx.doi.org/10.2174/1568026621666211004093647.
Imamura, Hideaki, Norikazu Ohtake, Hideki Jona, Aya Shimizu, Minoru Moriya, Hiroki Sato, Yuichi Sugimoto et al. „Dicationic dithiocarbamate carbapenems with anti-MRSA activity“. Bioorganic & Medicinal Chemistry 9, Nr. 6 (Juni 2001): 1571–78. http://dx.doi.org/10.1016/s0968-0896(01)00044-x.
Ohtake, Norikazu, Hideaki Imamura, Hideki Jona, Hideo Kiyonaga, Aya Shimizu, Minoru Moriya, Hiroki Sato, Masato Nakano, Ryosuke Ushijima und Susumu Nakagawa. „Novel dithiocarbamate carbapenems with anti-MRSA activity“. Bioorganic & Medicinal Chemistry 6, Nr. 7 (Juli 1998): 1089–101. http://dx.doi.org/10.1016/s0968-0896(98)00069-8.
Ohtake, Norikazu, Hideaki Imamura, Hideo Kiyonaga, Hideki Jona, Masayuki Ogawa, Shigemitsu Okada, Aya Shimizu et al. „Novel dithiocarbamate carbapenems1 with anti-MRSA activity“. Bioorganic & Medicinal Chemistry Letters 7, Nr. 13 (Juli 1997): 1617–22. http://dx.doi.org/10.1016/s0960-894x(97)00272-2.
Yee, Cheung, Donald Biek, Kevin Krause und Gregory Williams. „Ceftaroline: a Cephalosporin with Anti-MRSA Activity“. Clinical Microbiology Newsletter 33, Nr. 21 (November 2011): 161–69. http://dx.doi.org/10.1016/j.clinmicnews.2011.10.001.
Cao, Feng, Wei Peng, Xiaoli Li, Ming Liu, Bin Li, Rongxin Qin, Weiwei Jiang et al. „Emodin is identified as the active component of ether extracts from Rhizoma Polygoni Cuspidati, for anti-MRSA activity“. Canadian Journal of Physiology and Pharmacology 93, Nr. 6 (Juni 2015): 485–93. http://dx.doi.org/10.1139/cjpp-2014-0465.
Yu, Moxi, Yachen Hou, Meiling Cheng, Yongshen Liu, Caise Ling, Dongshen Zhai, Hui Zhao et al. „Antibacterial Activity of Squaric Amide Derivative SA2 against Methicillin-Resistant Staphylococcus aureus“. Antibiotics 11, Nr. 11 (28.10.2022): 1497. http://dx.doi.org/10.3390/antibiotics11111497.
Dissertationen zum Thema "Anti-MRSA activity":
Lima, Bruna de Araujo 1985. „Análise dos mecanismos da atividade antimicrobiana da violaceína sobre Staphylococcus aureus = Analysis of antimicrobial activity mechanisms of violacein against Staphylococcus aureus“. [s.n.], 2013. http://repositorio.unicamp.br/jspui/handle/REPOSIP/317022.
Tese (doutorado) - Universidade Estadual de Campinas, Instituto de Biologia
Made available in DSpace on 2018-08-23T15:34:06Z (GMT). No. of bitstreams: 1 Lima_BrunadeAraujo_D.pdf: 3794605 bytes, checksum: 178a4bf447e5292f789a4713d5500b38 (MD5) Previous issue date: 2013
Resumo: A violaceína é um pigmento violeta produzido por algumas espécies bacterianas de origem ambiental, tais como Chromobacterium violaceum e Janthinobacterium lividum. Esta molécula apresenta várias propriedades biológicas incluindo antibacteriana, antifúngica, antiviral, antiprotozoária e antitumoral, apesar de sua função exata na fisiologia dos micro-organismos que a produz, ainda é desconhecido. No presente trabalho, a atividade antimicrobiana da violaceína produzida comercialmente, o extrato semi purificado e nanopartículas de vanadato de prata foram avaliados contra espécies de bacterianas gram-positivas e gram-negativas. A violaceína exibiu efeito antimicrobiano contra Staphylococcus aureus resistente à meticilina (MRSA) e Enterococcus resistente à vancomicina (VRE), que são micro-organismos frequentemente relacionados com infecções adquiridas em hospitais. Os valores de MIC (concentração inibitória mínima) e MBC (concentração bactericida mínima) da violaceína produzida comercialmente foram de 0,625 ?M e 1,25 ?M respectivamente e, análise de curvas de crescimento e tempo-morte revelaram um efeito antibacteriano durante 12 horas contra MRSA. A microscopia eletrônica de transmissão mostrou os efeitos da violaceína com alterações morfológicas e ultra estruturais, incluindo alterações na parede celular e formação de septos de divisão anormais. Nos resultados obtidos das análises de proteômica e transcriptoma a violaceína afetou a expressão de várias classes funcionais de proteínas e genes em MRSA, incluindo processos biológicos em biossíntese da parede celular e divisão celular que corroboram as alterações ultra estruturais visualizadas. Em conclusão, a violaceína produzida comercialmente demonstrou atividade antimicrobiana para S. aureus MRSA e pela primeira vez, os efeitos da violaceína sobre o metabolismo de S. aureus foram descritos, indicando possíveis alvos e vias metabólicas afetadas por esta droga. No seu conjunto, estes dados indicam a violaceína como uma droga potencial para o tratamento de infecções provocadas por MRSA
Abstract: Violacein is a violet pigment produced by some bacterial species of environmental source, such as Chromobacterium violaceum and Janthinobacterium lividum. This molecule has numerous biological properties including antibacterial, antifungal, antiviral, antiprotozoal and antitumor activity, although the exact role in the physiology of producing microorganisms is still unknown. In this study, the antimicrobial activity of violacein produced commercially, semi purified extract and silver vanadate nanoparticles were evaluated against several species of gram-positive and gram-negative bacteria. Violacein exhibited antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE), microorganisms that are often related to hospital-acquired infections. MIC (minimum inhibitory concentration) and MBC (minimum bactericidal concentration) values of violacein produced commercially were 1.25 ?M mM and 0.625 ?M respectively, and analysis of growth and time-kill curves showed an antibacterial effect against MRSA for 12 hours. The transmission electron microscopy showed the effects of violacein with morphological and ultra-structural changes, including changes in cell wall formation and abnormal division septum. The results obtained from the analysis of proteomic and transcriptomic revealed that violacein affects the expression of several functional classes of proteins and genes in MRSA, including biological processes in cell wall biosynthesis and cell division, supporting ultra-structural changes. In conclusion, violacein produced commercially demonstrated antimicrobial activity against S. aureus MRSA and the effects on the metabolism of S. aureus have been described, indicating possible targets and pathways affected by this drug. These data indicate violacein as a potential drug for the treatment of infections caused by MRSA
Doutorado
Microbiologia
Doutora em Genética e Biologia Molecular
Bhattacharya, Biplob. „Synthesis and Anti-MRSA Activity of Hydrophilic C3-Acylated N-Thiolated β-Lactams and N-Acyl Ciprofloxacin-N-Thiolated β-Lactam Hybrids“. Scholar Commons, 2012. http://scholarcommons.usf.edu/etd/4289.
Hakem, Asma. „Les métabolites spécialisés du genre Juncus : approfondissement de leur potentiel antimicrobien et étude de leur biodisponibilité“. Electronic Thesis or Diss., Université de Lille (2022-....), 2023. https://pepite-depot.univ-lille.fr/ToutIDP/EDSMRE/2023/2023ULILR040.pdf.
To address the current challenges raised by emerging diseases (COVID-19 pandemic) and antibiotic resistance, the search for new antimicrobials has become urgent. The present study aims to highlight the potential of plant species, selected according to ecological and chemotaxonomic criteria, as a natural source of compounds with a wide structural diversity and promising biological activities. Juncus species collected from 3 localities in France were investigated for their potential antimicrobial effect against coronaviruses and Gram-positive bacterial strains. For this purpose, the approach of bioguided fractionation was adopted through the use of conventional separation techniques (preparative HPLC and CPC). The antiviral study conducted against the coronavirus HCoV-229E highlighted the antiviral potential of luteolin, a flavone that was isolated from the EtOAc sub-extract of J. acutus stems (locality 2). The screening for antibacterial activity led to the selection of the CH2Cl2 sub-extract of J. inflexus rhizomes (locality 3) for the rest of this study as this enriched-phenanthrene derivative sub-extract demonstrated a remarkable activity in particular against S. aureus strains. Additional experiments to deepen the understanding of the antibacterial effect of some of the isolated phenanthrene derivatives were performed focusing on a methicillin-resistant S. aureus strain that was isolated from a diabetic foot infection. Regarding the promising results, the developement of a topical formulation involving juncusol as an active component was initiated. Bioavailibility studies were also performed on this phenanthrene derivative through in vitro absorption and intestinal permeability experiments across Caco2/HT29-MTX co-cultured cells
Bücher zum Thema "Anti-MRSA activity":
Emami, Saeed. New quinolones with potential anti-MRSA activity. Hauppauge, N.Y: Nova Science, 2009.
Konferenzberichte zum Thema "Anti-MRSA activity":
Aunpad, Ratchaneewan, Siriporn Kaewklom und Watanalai Panbangred. „Two Putative Holin-Like Peptide with Anti-MRSA Activity and Their Potential Application“. In The Twenty-Third American and the Sixth International Peptide Symposium. Prompt Scientific Publishing, 2013. http://dx.doi.org/10.17952/23aps.2013.032.
Teixeira, Julia, Felipe Saraiva, Vinícius Gonçalves, Renata Bastos, Laianne Inácio, Juliana Boechat, Juliana Silva, Ana Argondizzo, Haroldo Júnior und José Senna. „Assessment of the activity of the anti-PBP2a monoclonal antibody from methicillin-resistant Staphylococcus aureus (MRSA) against Enterococcus spp“. In International Symposium on Immunobiological. Instituto de Tecnologia em Imunobiológicos, 2024. http://dx.doi.org/10.35259/isi.biomang.2024_63894.