Thematische Bibliographien / A. K. Gopalan

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Auswahl der wissenschaftlichen Literatur zum Thema „A. K. Gopalan“

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Veröffentlicht am 18. Mai 2024

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Zeitschriftenartikel zum Thema "A. K. Gopalan"

Jull, A. J. Timothy. „Principles of radiometric dating, by K. Gopalan. Cambridge, UK: Cambridge University Press, 2017, 224 p. $74.99. Hardback. Electronic copy will be available in future. $60.00. (ISBN 978-1-107-19873-9)“. Meteoritics & Planetary Science 53, Nr. 5 (25.01.2018): 1108–9. http://dx.doi.org/10.1111/maps.13047.

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Li, Xuan C., Yuelin Liu, Farid Rashidi Mehrabadi, Alejandro A. Schäffer, Drew Pratt, David R. Crawford, Salem Malikić et al. „Abstract 127: Single-cell methylation sequencing data reveals succinct metastatic migration histories and tumor progression models“. Cancer Research 83, Nr. 7_Supplement (04.04.2023): 127. http://dx.doi.org/10.1158/1538-7445.am2023-127.

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Abstract Recent studies exploring the impact of methylation in tumor evolution suggest that while the methylation status of many of the CpG sites are preserved across distinct lineages, others are altered as the cancer progresses. Since changes in methylation status of a CpG site may be retained in mitosis, they could be used to infer the progression history of a tumor via single-cell lineage tree reconstruction. In this work, we introduce the first principled distance-based computational method, Sgootr, for inferring a tumor's single-cell methylation lineage tree and jointly identifying lineage-informative CpG sites which harbor changes in methylation status that are retained along the lineage. We apply Sgootr on the single-cell bisulfite-treated whole genome sequencing data of multiregionally-sampled tumor cells from 9 metastatic colorectal cancer patients made available by Bian et al., as well as multiregionally-sampled single-cell reduced-representation bisulfite sequencing data from a glioblastoma patient made available by Chaligne et al. We demonstrate that the tumor lineages constructed reveal a simple model underlying colorectal tumor progression and metastatic seeding. A comparison of Sgootr against alternative approaches shows that Sgootr can construct lineage trees with fewer migration events and more in concordance with the sequential-progression model of tumor evolution, in time a fraction of that used in prior studies. Interestingly, lineage-informative CpG sites identified by Sgootr are in inter-CpG island (CGI) regions, as opposed to CGI's, which have been the main regions of interest in genomic methylation-related analyses. Sgootr is implemented as a Snakemake workflow, available at https://github.com/liuy0421/Sgootr. Citation Format: Xuan C. Li, Yuelin Liu, Farid Rashidi Mehrabadi, Alejandro A. Schäffer, Drew Pratt, David R. Crawford, Salem Malikić, Erin K. Molloy, Vishaka Gopalan, Stephen M. Mount, Eytan Ruppin, Kenneth Aldape, S. Cenk Sahinalp. Single-cell methylation sequencing data reveals succinct metastatic migration histories and tumor progression models [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 127.

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Glen, David. „Integrated Pest Management in the Tropics: Current Status and Future Prospects. Edited by A. N. Mangech, K. N. Saxena and H. N. B. Gopalan. Chichester and New York: John Wiley (1995), pp. 171, £35.00. ISBN 0-1471-96076-4.“ Experimental Agriculture 33, Nr. 2 (April 1997): 247–52. http://dx.doi.org/10.1017/s0014479797220119.

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Khaled, Annette R., James Velazquez, Lam Truong, Colten Frank, Carolyn Dang, Amanda Cox, Heba Ghozlan, Eunkyung Lee, Amr S. Khaled und Priya K. Gopalan. „Abstract 2463: Protein folding chaperonin as biological indicator for cancer progression and metastasis“. Cancer Research 83, Nr. 7_Supplement (04.04.2023): 2463. http://dx.doi.org/10.1158/1538-7445.am2023-2463.

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Abstract Protein folding complexes are a vital link between the expression of tumor-promoting oncogenes and oncogenic cancer behavior known as the hallmarks of cancer. Of these, the eukaryotic type II chaperonin, Chaperonin-Containing TCP-1 (CCT or TRiC) folds many of the oncoproteins (e.g., KRAS, MYC, CDKs, STAT3, etc.) that drive cancer growth and invasion. CCT is a complex machine composed of eight subunits, each encoded by a unique gene (cct1-8), which folds proteins in an ATP-dependent fashion within an inner chamber. Previous work in breast cancer revealed that the CCT2 subunit was highly expressed in breast tumor tissues and correlated with advanced breast cancer stage, metastasis, and decreased patient survival. To determine the pattern of CCT2 expression across multiple cancers in comparison to normal tissues, we interrogated the UCSC Xena database to compare cohorts, GTEx (normal tissues), TCGA (adult cancerous and normal tissues), and TARGET (pediatric cancerous and normal tissues). Tumor specimens from adult TCGA expressed significantly higher levels of CCT2 than GTEx, and pediatric TARGET samples had significantly higher expression levels of CCT2 than TCGA and normal samples. Histological detection of CCT2 in multiple cancer tissues was increased (e.g., pediatric cancers and sarcomas being among the highest) compared to cancer-adjacent tissues or normal tissues and supported the bioinformatics data. Manipulating CCT2 levels in individual breast, neuroblastoma, and prostate cancer cells revealed the strategic importance of this chaperonin subunit in supporting the metastatic cancer phenotype. Exogenous expression of CCT2 promoted uncontrolled and anchorage-independent growth and migration of cancer cells, which was reversed upon depletion of the subunit, causing cancer cell death. Moreover, conditioned media from cancer cells exogenously expressing CCT2 also drove the migration and growth of cancer cells. Exosomes isolated from this media contained high levels of CCT2 mRNA, further demonstrating the metastasis-promoting potential of this chaperonin subunit. The feasibility of using CCT2 as a biomarker to detect cancer progression was confirmed using antibodies to detect CCT2 in the identification of circulating tumor cells using the CellSearch System. These results provide validation to further develop the use of CCT2 as a diagnostic marker for cancer progression and metastasis and as a promising therapeutic target for new drug development. Citation Format: Annette R. Khaled, James Velazquez, Lam Truong, Colten Frank, Carolyn Dang, Amanda Cox, Heba Ghozlan, Eunkyung Lee, Amr S. Khaled, Priya K. Gopalan. Protein folding chaperonin as biological indicator for cancer progression and metastasis [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2023; Part 1 (Regular and Invited Abstracts); 2023 Apr 14-19; Orlando, FL. Philadelphia (PA): AACR; Cancer Res 2023;83(7_Suppl):Abstract nr 2463.

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Rahman, MA, R. Abka, MS Rahman und PK Sarma. „Poverty and food security analysis: A study of fishermen households in a selected area of Bangladesh“. Journal of the Bangladesh Agricultural University 11, Nr. 2 (10.08.2014): 293–300. http://dx.doi.org/10.3329/jbau.v11i2.19928.

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This study examines the poverty and food security analysis of fishermen households in a selected area of Gopalganj Sadar Upazila in Gopalganj District in Bangladesh. A sample size of 60 households was selected purposively from four villages. Data was collected through field survey by using pre-designed and pre-tested questionnaire. Calorie intake levels were calculated and statistical comparisons were done. Multiple regression analysis was carried out to determine the factor influencing calorie intake in individual levels. Food consumption scores were used to determine calorie intake levels. The major findings of the study were that income, education, cultivable area and rented area had positive impact on calorie intake but age of the respondents and family size had negative impact on calorie intake. About 68.33% of the respondents belonged to hard core poor whose average calorie intake was 1692.32 k. calories and 25% of the respondents had an average calorie intake 1890.93 k. calories and they belonged to absolute poor. The rest 6.67 % of the respondents took above 2122 kilo calories and average calorie intake was 2193.50 k. calories. There was 20% households having poor food consumption and 42% having borderline food consumption. Only 6.67% fishermen households have acceptable low food consumption and 3.33% have acceptable high food consumption. DOI: http://dx.doi.org/10.3329/jbau.v11i2.19928 J. Bangladesh Agril. Univ. 11(2): 293-299, 2013

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J, Sudarvizhi. „Ethnographic Datas of Karisal Land in Gopalla Gramam Novel“. International Research Journal of Tamil 4, S-4 (06.07.2022): 7–15. http://dx.doi.org/10.34256/irjt22s42.

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The intellectual anthropology that studies human beings examines human beings and human society at three levels: biological anthropology, social anthropology, and cultural anthropology. It is ethnography to trace the culture of a particular group of people in Tamilnadu, where different cultures and customs prevail. In that respect, the purpose of this study is to find ethnographic data in the novel Gopalla Gramam by the author K. Rajanarayanan, based on the biographies of the people of the Karisal area. In this study, the concepts like "what is ethnography? What are the cultural researchers' references to data to identify them? How are the data on food, artefacts, beliefs, customs, agriculture, plants, animals, birds, land, water, vernaculars, stories, songs, etc., recorded in the Gopalla Gramam novel to define the ethnography of the Karisal soil" have been identified. How they represent the uniqueness and identity of the black soil is also under scrutiny.

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Sharma, V., und N. Thakur. „Microwave Dielectric Study of Tetramethylurea andN, N-Dimethylacetamide Binary Mixture in Benzene“. E-Journal of Chemistry 8, Nr. 3 (2011): 1378–86. http://dx.doi.org/10.1155/2011/329637.

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Dielectric relaxation of the binary mixture of tetramethylurea andN, N-dimethylacetamide has been studied at fixed frequency and temperature (9.88 GHz & 298 K respectively) in benzene solution. Different dielectric parameters like the dielectric constant (ε') and the dielectric loss (ε") at microwave frequency, static dielectric constant (ε0) and dielectric constant (ε∞) at optical frequency were determined. The values of relaxation time (τ(1), τ(2), τ(0)& τGK) have been calculated using higasi’s single frequency method and Gopala Krishna’s method. Using Eyring’s rate theory, the activation energies for the process of dielectric relaxation and viscous flow were calculated and compared. The study of dielectric properties of the binary mixture reveals the existence of the solute-solute type of molecular associations.

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Stallings, W. M. „Book Reviews : 100 Statistical Tests, by Gopal K. Kanji. Newbury Park, CA: Sage Publications, 1993, 216 pp“. American Journal of Evaluation 16, Nr. 1 (01.02.1995): 81–83. http://dx.doi.org/10.1177/109821409501600112.

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Lis, Andrzej. „BOOK REVIEW: IN A TRIBUTE TO PROFESSOR GOPAL K. KANJI: THE EDITED COLLECTION "QUALITY, EXCELLENCE AND MEASUREMENT"“. Journal of Positive Management 6, Nr. 1 (13.09.2015): 71. http://dx.doi.org/10.12775/jpm.2015.006.

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Colton, D. „100 Methods for Total Quality Management Gopal K. Kanji and Mike Asher. Newbury Park, CA: Sage, 1996,237 pp.“ American Journal of Evaluation 19, Nr. 2 (1998): 273–75. http://dx.doi.org/10.1016/s1098-2140(99)80210-0.

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Dissertationen zum Thema "A. K. Gopalan"

Kundu, Indrani. „Paradigm shifts in jurisprudential thoughts in Indian legal system: study of A.K. Gopalan to Maneka Gandhis case and beyond“. Thesis, University of North Bengal, 2021. http://ir.nbu.ac.in/handle/123456789/4233.

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Bücher zum Thema "A. K. Gopalan"

Gupta, Gopal K. Māyā in the Bhāgavata Purāṇa. Oxford University Press, 2020. http://dx.doi.org/10.1093/oso/9780198856993.001.0001.

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The idea of māyā pervades Indian philosophy: it is complex, multivalent, and foundational, with its oldest referents found in the Ṛg -veda. This book explores māyā’s rich conceptual history, and then focuses on the highly developed theology of māyā found in the Sanskrit Bhāgavata Purāṇa, one of the most important Hindu sacred texts. Gopal K. Gupta examines māyā’s role in the Bhāgavata’s narratives, paying special attention to māyā’s relationship with other key concepts in the text, such as human suffering (duḥkha), devotion (bhakti), and divine play (līlā). In the Bhāgavata, māyā is often identified as the divine feminine, and her scope and influence are far-reaching—māyā is the world and the means by which God creates the world, she is the power that deludes living beings and ensorcells them in the phenomenal world, and she is the facilitator of God’s play, paradoxically revealing him to his devotees by concealing his majesty. While Vedānta philosophy typically sees māyā as a negative force, the Bhāgavata affirms that māyā also has a positive role, for in both the conditioned and liberated states, māyā is meant to ultimately draw living beings toward Kṛṣṇa and intensify their love for him.

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Buchteile zum Thema "A. K. Gopalan"

„Speech by A. K. Gopalan, a Member of Parliament, arrested during the Emergency“. In Independent India, 1947-2000, 194. Routledge, 2018. http://dx.doi.org/10.4324/9781315838212-46.

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Taber, Douglass F. „Functional Group Protection“. In Organic Synthesis. Oxford University Press, 2015. http://dx.doi.org/10.1093/oso/9780190200794.003.0011.

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Zhong-Jun Li of Peking University developed (J. Org. Chem. 2011, 76, 9531) a Co catalyst for selectively replacing one benzyl protecting group of 1 with silyl. Carlo Unverzagt of Universität Bayreuth devised (Chem. Commun. 2011, 47, 10485) oxidative conditions for debenzylating the azide 3 to 4. Tadashi Katoh of Tohoku Pharmaceutical University found (Tetrahedron Lett. 2011, 52, 5395) that the dimethoxybenzyl protecting group of 5 could be selectively removed in the presence of benzyl and p-methoxybenzyl. Scott T. Phillips of Pennsylvania State University showed (J. Org. Chem. 2011, 76, 7352) that in the presence of phosphate buffer, catalytic fluoride was sufficient to desilylate 7. Philip L. Fuchs of Purdue University employed (J. Org. Chem. 2011, 76, 7834, not illustrated) the neutral Robins conditions (Tetrahedron Lett. 1992, 33, 1177) to effect a critical desilylation. Pengfei Wang of the University of Alabama at Birmingham found (J. Org. Chem. 2011, 76, 8955) that an excess of the diol 9 both oxidized the primary alcohol 10 and installed the photolabile protecting group on the product aldehyde. Hiromichi Fujioka of Osaka University showed (Angew. Chem. Int. Ed. 2011, 50, 12232) that addition of Ph3P to 12 transiently protected the aldehyde, allowing selective reduction of the ketone to the alcohol. Willi Bannwarth of Albert-Ludwigs-Universität Freiburg deprotected (Angew. Chem. Int. Ed. 2011, 50, 6175) the chelating amide of 14, leaving the usually sensitive Fmoc group in place. Bruce C. Gibb, now at Tulane University, hydrolyzed (Nature Chem. 2010, 2, 847) 16 more rapidly than the very similar 17, by selective equilibrating complexation of 16 and 17 with a cavitand. Aravamudan S. Gopalan of New Mexico State University converted (Tetrahedron Lett. 2010, 51, 6737) proline 19 to the amide ester 10 by exposure to triethyl orthoacetate. K. Rajender Reddy of the Indian Institute of Chemical Technology oxidized (Angew. Chem. Int. Ed. 2011, 50, 11748) the formamide 22 to the carbamate 23 by exposure to H2O2 in the presence of 21. James M. Boncella of the Los Alamos National Laboratory deprotected (Org. Lett. 2011, 13, 6156) 24 by exposure to visible light in the presence of a Ru catalyst.

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„INTELLIGENT ROUTING IN GRADED COGNITIVE NETWORKS T. R. GOPALAKR ISHNAN NA IR AND K AV ITHA SOODA“. In Cognitive Networks, 371–90. CRC Press, 2014. http://dx.doi.org/10.1201/b17877-16.

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