Zeitschriftenartikel: „2GDT“

1

Andrews, GA, PS Chavey, JE Smith und L. Rich. „N-glycolylneuraminic acid and N-acetylneuraminic acid define feline blood group A and B antigens“. Blood 79, Nr. 9 (01.05.1992): 2485–91. http://dx.doi.org/10.1182/blood.v79.9.2485.2485.

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Abstract Blood group incompatibility causes transfusion reactions and neonatal isoerythrolysis in cats. We investigated the molecular nature of the blood group antigens from cats that had blood type A, B, and AB erythrocytes. Naturally occurring anti-type B antibodies, Triticum vulgaris lectin, monoclonal antibody (MoAb) 32–27, and MoAb R-24 were used in agglutination tests, Western blots, and thin-layer chromatography (TLC) enzyme immunostaining. Type A erythrocytes had NeuGc-NeuGc-Galactose-Glucose-Ceramide ([NeuGc]2GD3) where NeuGc represents N-glycolylneuraminic acid, and NeuAc-NeuGc-GD3, where NeuAc represents N-acetylneuraminic acid, and may have [NeuGc]2 disialylparagloboside and NeuAc-NeuGc-disialylparagloboside. Type B erythrocytes only had [NeuAc]2GD3. Type AB erythrocytes had [NeuGc]2GD3, NeuAc-NeuGc-GD3, and [NeuAc]2GD3. Blood group antigens were also found on a 50-Kd membrane protein. We conclude that type B erythrocytes are characterized by [NeuAc]2GD3 as the only form of this ganglioside and the presence of NeuAc on a 50-Kd membrane protein. NeuGc is the major determinant of the A antigen; specifically, [NeuGc]2GD3 is the major glycolipid form. The A antigen is also present on a 50-Kd membrane protein.

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Andrews, GA, PS Chavey, JE Smith und L. Rich. „N-glycolylneuraminic acid and N-acetylneuraminic acid define feline blood group A and B antigens“. Blood 79, Nr. 9 (01.05.1992): 2485–91. http://dx.doi.org/10.1182/blood.v79.9.2485.bloodjournal7992485.

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Blood group incompatibility causes transfusion reactions and neonatal isoerythrolysis in cats. We investigated the molecular nature of the blood group antigens from cats that had blood type A, B, and AB erythrocytes. Naturally occurring anti-type B antibodies, Triticum vulgaris lectin, monoclonal antibody (MoAb) 32–27, and MoAb R-24 were used in agglutination tests, Western blots, and thin-layer chromatography (TLC) enzyme immunostaining. Type A erythrocytes had NeuGc-NeuGc-Galactose-Glucose-Ceramide ([NeuGc]2GD3) where NeuGc represents N-glycolylneuraminic acid, and NeuAc-NeuGc-GD3, where NeuAc represents N-acetylneuraminic acid, and may have [NeuGc]2 disialylparagloboside and NeuAc-NeuGc-disialylparagloboside. Type B erythrocytes only had [NeuAc]2GD3. Type AB erythrocytes had [NeuGc]2GD3, NeuAc-NeuGc-GD3, and [NeuAc]2GD3. Blood group antigens were also found on a 50-Kd membrane protein. We conclude that type B erythrocytes are characterized by [NeuAc]2GD3 as the only form of this ganglioside and the presence of NeuAc on a 50-Kd membrane protein. NeuGc is the major determinant of the A antigen; specifically, [NeuGc]2GD3 is the major glycolipid form. The A antigen is also present on a 50-Kd membrane protein.

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Vladimirova, Liubov Yu, Oleg Ivanovich Kit, Elena A. Nikipelova und Natalya A. Abramova. „Results of monoclonal antibodies against EGFR-receptors application in patients with metastatic colorectal cancer (mCRC).“ Journal of Clinical Oncology 31, Nr. 15_suppl (20.05.2013): e14701-e14701. http://dx.doi.org/10.1200/jco.2013.31.15_suppl.e14701.

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e14701 Background: Monoclonal antibodies against the epidermal growth factor receptor(EGFR)are standard components of treatment in mCRC.This study was designed to evaluate the tolerability and efficacy of the combinations of Panitumumab(P) and Cetuximab(C) with chemotherapy in patients with wild type(WT) KRAS tumors mCRC. Methods: Mutation analysis of KRAS(codons12,13) was done on samples at diagnosis. Key elegibility criteria included measurable mCRC stage IV, ECOG ≤2, adequate liver,kidney and bone marrow function, no brain metastases. P was administered 6mg/ kg 1 day q2w. C was administered 400mg/m² 1day and 250mg/m² q1w. Combination with FOLFOX-6 or FOLFIRI pegimens was allowed. Endpoints include response rate, OS, PFS and safety. Results: Of 38 testable samples there were 21(55.3%) WT KRAS tumors. All of these 21 (13male and 8female) pts were recruited. Mean age was 58.1±12.3. Synchronous metastases had 33.3%(7pts). Majority of pts benefited from anti-EGFR combined with cytotoxic chemotherapy 80.9% (17), mostly FOLFIRI – 57,1%(12).There were23.8%(5) in the 1st line CT, 76.1%(16) in the 2nd line CT. 6 mos of the treatment were analyzed. Overall RR was76.1 %(16) including 6PR(28.5%) and 10SD(47.6%). Med OS= 9.1mo, Med PFS= 4.3mo. 8 pts(38.1%) are alive till the abstract submission. Most common toxicities were:skin rash 2/3Gd.-90.5%(19), xeroderma 2Gd.-42.9%(9),skin itch 1/3Gd.-42.9%(9), paronychia 2Gd. -14.2%(3), purulent psorophthalmia 2Gd.-14.2%(3). All kinds of toxicities were controlled by symptomatic medication if necessary and did not lead to anti-EGFR agents dalay. Besides,diarrhea 1/2Gd.- 66.7%(14), 3Gd.-14.3%(3), neutropenia 1/2Gd.-28.6%(6), 3/4Gd.-9.5%(2), nausea 3/4Gd.- 14.3%(3), vomiting 1/2Gd.- 42.9%(9), fatigue 1/2Gd.-47.6%(10). Conclusions: These results consider significant efficacy of anti-EGFR agents combined with CT in pts with mCRC. Controlled toxicity of the therapy allows to use it widely.

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Дудникова, В. Б., Д. И. Антонов, Е. В. Жариков und Н. Н. Еремин. „Твердые растворы CaMoO-=SUB=-4-=/SUB=--NaGd(MoO-=SUB=-4-=/SUB=-)-=SUB=-2-=/SUB=-: моделирование свойств и локальной структуры методом межатомных потенциалов“. Физика твердого тела 64, Nr. 11 (2022): 1741. http://dx.doi.org/10.21883/ftt.2022.11.53328.413.

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Проведено моделирование твердых растворов CaMoO4-NaGd(MoO4)2 методом межатомных потенциалов. Показано, что твердые растворы существуют во всем диапазоне составов и близки к идеальным. Получены зависимости от состава параметров и объема элементарной ячейки, плотности, модуля объемной упругости, энтальпии, колебательной энтропии и теплоемкости. Построены температурные зависимости теплоемкости и колебательной энтропии. Анализ локальной структуры и ее изменения в зависимости от состава твердого раствора Ca1-xNax/2Gdx/2MoO4 показал, что в твердом растворе межатомные расстояния Gd-O в среднем на 2.62% меньше, а Na-O на 3.15% больше расстояний Ca-O. В целом это приводит к увеличению параметров и объема элементарной ячейки при образовании твердых растворов Ca1-xNax/2Gdx/2MoO4 по сравнению с CaMoO4. Ключевые слова: моделирование, молибдаты, твердые растворы, локальная структура.

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Kerkelä, Risto, Sara Karsikas, Zoltan Szabo, Raisa Serpi, Johanna Magga, Erhe Gao, Kari Alitalo et al. „Activation of Hypoxia Response in Endothelial Cells Contributes to Ischemic Cardioprotection“. Molecular and Cellular Biology 33, Nr. 16 (17.06.2013): 3321–29. http://dx.doi.org/10.1128/mcb.00432-13.

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Small-molecule inhibition of hypoxia-inducible factor prolyl 4-hydroxylases (HIF-P4Hs) is being explored for the treatment of anemia. Previous studies have suggested that HIF-P4H-2 inhibition may also protect the heart from an ischemic insult.Hif-p4h-2gt/gtmice, which have 76 to 93% knockdown ofHif-p4h-2mRNA in endothelial cells, fibroblasts, and cardiomyocytes and normoxic stabilization of Hif-α, were subjected to ligation of the left anterior descending coronary artery (LAD). Hif-p4h-2 deficiency resulted in increased survival, better-preserved left ventricle (LV) systolic function, and a smaller infarct size. Surprisingly, a significantly larger area of the LV remained perfused during LAD ligation inHif-p4h-2gt/gthearts than in wild-type hearts. However, no difference was observed in collateral vessels, while the size of capillaries, but not their number, was significantly greater inHif-p4h-2gt/gthearts than in wild-type hearts.Hif-p4h-2gt/gtmice showed increased cardiac expression of endothelial Hif target genes for Tie-2, apelin, APJ, and endothelial nitric oxide (NO) synthase (eNOS) and increased serum NO concentrations. Remarkably, blockage of Tie-2 signaling was sufficient to normalize cardiac apelin and APJ expression and resulted in reversal of the enlarged-capillary phenotype and ischemic cardioprotection inHif-p4h-2gt/gthearts. Activation of the hypoxia response by HIF-P4H-2 inhibition in endothelial cells appears to be a major determinant of ischemic cardioprotection and justifies the exploration of systemic small-molecule HIF-P4H-2 inhibitors for ischemic heart disease.

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Tian, He, Liangliang Wei und Limin He. „Phase Composition and Stability, Sintering and Thermal Conductivity of Gd2O3 and Yb2O3 Co-Doped YSZ“. Coatings 13, Nr. 1 (28.12.2022): 53. http://dx.doi.org/10.3390/coatings13010053.

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Y2O3-stabilized ZrO2 (YSZ) has been the material of choice for thermal barrier coatings (TBCs) in the past decades, yet its phase decomposition limits its application above 1200 °C. In this study, Gd2O3 and Yb2O3 co-doped YSZ powders were produced, in which some amounts of monoclinic (m) phase were introduced into the cubic (c) phase matrix. XRD results showed that the fabricated powders obtained by a solid phase synthesis were composed of m and c phases, and hat the m phase content decreased in a sequence of 4Gd-2Yb-4Y, 2Gd-2Yb-6Y and 2Gd-4Yb-4Y powders. This indicated that Yb3+ is an excellent stabilizer in the ZrO2-based lattice, which could largely suppress the formation of the m phase. The m phase content in the powders was almost kept unchanged with heating at 1300 °C, which could provide a toughening effect to the ceramic. All the powders exhibited no obvious sintering at 1300 °C for 150 h. As compared to YSZ, the three fabricated ceramics had lower thermal conductivities, and they increased in a sequence of 4Gd-2Yb-4Y, 2Gd-4Yb-4Y and 2Gd-2Yb-6Y.

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Dudnikova V. B, Antonov D. I., Zharikov E. V. und Eremin N. N. „CaMoO-=SUB=-4-=/SUB=--NaGd(MoO-=SUB=-4-=/SUB=-)-=SUB=-2-=/SUB=- Solid Solutions: simulation of properties and local structure by the method of interatomic potentials“. Physics of the Solid State 64, Nr. 11 (2022): 1713. http://dx.doi.org/10.21883/pss.2022.11.54195.413.

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Simulation of CaMoO4-NaGd(MoO4)2 solid solutions by the method of interatomic potentials is carried out. It is shown that solid solutions exist in the entire range of compositions and are close to ideal. Dependences on the composition of the lattice parameters and volume of the unit cell, density, bulk modulus, enthalpy, vibrational entropy and heat capacity are obtained. Temperature dependences of heat capacity and vibrational entropy are constructed. Analysis of the local structure and its changes depending on the composition of the Ca1-xNax/2Gdx/2MoO4 solid solution showed that in solid solution the interatomic distances of Gd-O are on average 2.62% less, and Na-O is 3.15% greater than the distances of Ca-O. In general, this leads to an increase in the lattice parameters and volume of the unit cell during the formation of Ca1-xNax/2Gdx/2MoO4 solid solutions compared to CaMoO4. Keywords: simulation, molybdates, the solid solutions, local structure.

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Laitala, Anu, Ellinoora Aro, Gail Walkinshaw, Joni M. Mäki, Maarit Rossi, Minna Heikkilä, Eeva-Riitta Savolainen et al. „Transmembrane prolyl 4-hydroxylase is a fourth prolyl 4-hydroxylase regulating EPO production and erythropoiesis“. Blood 120, Nr. 16 (18.10.2012): 3336–44. http://dx.doi.org/10.1182/blood-2012-07-441824.

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AbstractAn endoplasmic reticulum transmembrane prolyl 4-hydroxylase (P4H-TM) is able to hydroxylate the α subunit of the hypoxia-inducible factor (HIF) in vitro and in cultured cells, but nothing is known about its roles in mammalian erythropoiesis. We studied such roles here by administering a HIF-P4H inhibitor, FG-4497, to P4h-tm−/− mice. This caused larger increases in serum Epo concentration and kidney but not liver Hif-1α and Hif-2α protein and Epo mRNA levels than in wild-type mice, while the liver Hepcidin mRNA level was lower in the P4h-tm−/− mice than in the wild-type. Similar, but not identical, differences were also seen between FG-4497–treated Hif-p4h-2 hypomorphic (Hif-p4h-2gt/gt) and Hif-p4h-3−/− mice versus wild-type mice. FG-4497 administration increased hemoglobin and hematocrit values similarly in the P4h-tm−/− and wild-type mice, but caused higher increases in both values in the Hif-p4h-2gt/gt mice and in hematocrit value in the Hif-p4h-3−/− mice than in the wild-type. Hif-p4h-2gt/gt/P4h-tm−/− double gene-modified mice nevertheless had increased hemoglobin and hematocrit values without any FG-4497 administration, although no such abnormalities were seen in the Hif-p4h-2gt/gt or P4h-tm−/− mice. Our data thus indicate that P4H-TM plays a role in the regulation of EPO production, hepcidin expression, and erythropoiesis.

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Hu, Yaobo, Chao Zhang, Tianxu Zheng, Fusheng Pan und Aitao Tang. „Strengthening Effects of Zn Addition on an Ultrahigh Ductility Mg-Gd-Zr Magnesium Alloy“. Materials 11, Nr. 10 (11.10.2018): 1942. http://dx.doi.org/10.3390/ma11101942.

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A newly developed Mg-2Gd-0.5Zr-xZn (x = 0.5, 1.0, 2.0, 3.0 wt %) alloy system exhibits significant strengthening by doping with Zn. In order to understand the strengthening mechanism, the microstructure, texture evolution, and mechanical properties of ultrahigh ductility Mg-2Gd-0.5Zr alloys with a Zn addition were systematically investigated. The addition of Zn results in the formation of Mg-Gd-Zn intermetallic compounds along grain boundaries, which encourages grain refinement during hot extrusion via the particle stimulated nucleation (PSN) mechanism. Furthermore, during texture sharpening the pole changes from <20 2 ¯ 1> to <01 1 ¯ 0>, which also occurred in the extruded alloys with Zn addition, which is unfavorable for the basal slip and tensile twinning. Mg-2Gd-0.5Zr-3Zn shows well-balanced strength and ductility with a tensile yield strength (YS) and ultimate tensile strength (UTS) of 285 and 314 MPa, accompanied by a high tensile elongation of 24%. They are superior to those of commercial AZ31. The enhanced strength is attributed to grain refinement, precipitation strengthening, and texture sharpening induced by alloying with Zn. The research result is also of great value to the development of low rare-earth, high strength, and high room temperature ductility magnesium alloy.

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Myllymäki, Mikko, Jenni Määttä, Elitsa Dimova, Valerio Izzi, Timo Väisänen, Johanna Myllyharju, Peppi Koivunen und Raisa Serpi. „Extramedullary Erythropoiesis in Spleen of HIF Prolyl 4-Hydroxylase-2 Deficient Mice Is Mediated By Notch Signaling Downregulation“. Blood 128, Nr. 22 (02.12.2016): 2656. http://dx.doi.org/10.1182/blood.v128.22.2656.2656.

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Abstract Erythrocytosis, an increase in absolute red cell mass, is mainly driven by erythropoietin, while hypoxia-inducible factor (HIF) regulates the expression of a number of genes involved in it, including erythropoietin. Mutations in HIF prolyl 4-hydroxylase 2 (HIF-P4H-2/PHD2/EGLN1), the major regulator of the stability of HIFα subunits, are found in familiar erythrocytosis, and large-spectrum conditional inactivation of HIF-P4H-2 in mice leads to severe erythrocytosis and premature death. Although bone marrow is the primary site for erythropoiesis, spleen retains a capability for extramedullary erythropoiesis. We studied HIF-P4H-2 hypomorphic mice (Hif-p4h-2gt/gt) which show slightly induced erythropoiesis only upon aging despite no increased erythropoietin levels. Spleen was identified as the site of extramedullary erythropoiesis in these mice. Hematopoietic stem cells (HSCs) from spleens of the Hif-p4h-2gt/gt mice showed increased growth of BFU-Es and the mice were protected against anemia by induced extramedullary erythropoiesis. HIF-1α and HIF-2α were stabilized in the spleens, while the Notch ligands and target Jag1, Jag2, Dll1 and Hes1 became downregulated upon aging dependent on HIF-2α. Inhibition of Notch signaling in wild-type spleen HSCs phenocopied the increased growth of BFU-Es in the Hif-p4h-2gt/gt mice. We conclude that HIFα stabilization can mediate non-erythropoietin-driven extramedullary erythropoiesis in the spleen via altered Notch signaling. Disclosures Myllyharju: FibroGen Inc.: Equity Ownership, Research Funding.

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Barik, Subrat K., R. N. P. Choudhary und P. K. Mahapatra. „Structural and electrical properties of Na1/2Gd1/2TiO3 nanoceramics“. Journal of Alloys and Compounds 459, Nr. 1-2 (Juli 2008): 35–40. http://dx.doi.org/10.1016/j.jallcom.2007.04.301.

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Liu, Jianxin, Jun Chen, Quanan Li, Xiaoya Chen und Ziyan Zhang. „Effect of aging treatment on corrosion behavior of Mg-4Nd-2Gd-0.5Zr alloy“. Materials Research Express 9, Nr. 1 (01.01.2022): 016503. http://dx.doi.org/10.1088/2053-1591/ac452c.

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Abstract The effects of aging time on corrosion behavior of Mg-4Nd-2Gd-0.5Zr alloy in 3.5% NaCl solution were investigated by microanalysis, weight loss test and electrochemical test. The results show that the corrosion rate of Mg-4Nd-2Gd-0.5Zr alloy decreases first and then increases with the extension of aging time. Aging treatment alters the grain size and the distribution of the second phases. The second phases and grain size are the key factors affecting the corrosion rate of magnesium alloy. Among the tested alloys, the T6-8 h alloy shows the lowest corrosion rate, which is mainly attributed to the continuous distribution of second phases restricting the expansion of corrosion, hence the T6-8 h alloy showed the highest corrosion resistance. The corrosion rate of T6-16 h alloy increases obviously because of the growth of the grain size and the segregation of second phases, which accelerates the corrosion progress.

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Maridaki-Kassotaki, Katerina, und Norman H. Freeman. „Concepts of Pictures on Display“. Empirical Studies of the Arts 18, Nr. 2 (Juli 2000): 151–58. http://dx.doi.org/10.2190/24y7-2gdj-ax1a-0rg2.

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When do viewers acquire a fully explicit unprompted concept of what is communicatively important about displays of pictures? On two trials, one week apart, 120 Greek informants explained what a kadro is. The Greek term kadro literally means frame, but also means “that which has been framed as a display piece.” Children aged four and eight years represented these important artefacts only as furnishings. Adults and adolescents referred to 1) commemoration of artists' achievement, and 2) public display of taste and judgment.

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Rudlowski, MD, Christian, Albert J. Becker, Willibald Schroder, Werner Rath, MD, Reinhard BÜttner, MD und Markus Moser, PhD. „GLUT1 Messenger RNA and Protein Induction Relates to the Malignant Transformation of Cervical Cancer“. American Journal of Clinical Pathology 120, Nr. 5 (01.11.2003): 691–98. http://dx.doi.org/10.1309/4kyn-qm58-62jw-2gd7.

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Vladimirova, Liubov Yu, und Oleg I. Kit. „Long-term results of capicitabine application in metastatic breast cancer patients.“ Journal of Clinical Oncology 30, Nr. 15_suppl (20.05.2012): e11558-e11558. http://dx.doi.org/10.1200/jco.2012.30.15_suppl.e11558.

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e11558 Background: Options available after the failure of anthracyclines and taxanes are very limited in BC patients. The long-term experience of Cap application brought us to analyse long-term results of the treatment in this patients. Methods: pts progressed after anthracyclines and taxanes were recruited in 2000-2010. Key elegibility criteria included measurable or nonmeasurable triple-negative MBC or locally recurrent disease, ECOG ≤2, no brain metastases. Cap was administered 1250 mg/ m² BID 1-14 days q3w. Treatment was continued until progression or unacceptable toxicity. A total of 266 courses were estimated. Endpoints include response rate, OS, PFS and safety. Results: 63 patients aged 30-80 years were recruited. 92% had infiltrative ductal carcinoma, triple negative. Time to disease progression was 2.5 mon.- 16 years(mean- 2.6 years). 22% (14) had one disease site: liver 5, lung 5, bones 3, lymphonodes 1. The rest 78% (49)had ≥2 disease sites: lung 32(50.8%), bones 30(47.6%), liver 33(52.3%), soft tissues 21(33.3%). Mean # of disease sites = 2.06. Overal RR was 63.5%(40) including 4 CR(6.3%), 6PR(9.5%) and 30SD(47.6%). Med OS= 9mo, Med PFS= 5 mo. For detailed survival analysis patients were devided into two groups: 1) with RR (40 pts); 2) without RR (23 pts). Med OS was 13 v 4 months (p=0.00004), Med PFS was 6 v 3months respectively(p=0.00016). 8 pts(12.7%) are alive till the abstract submission. Main hematological toxicity was leucopenia1/2 Gd-28.6%, neutropenia 1/2Gd.-26.3%, anemia 1/2 Gd.-19.9%, thrombocytopenia 1/2Gd.- 3.1% courses. Nonhematological toxicity included nausea 1/2 Gd.- 28.5%, vomiting 1/2Gd.- 12.5% and diarrhea 1/2 -16%, hand-foot syndrome 1/2 Gd.-16.9%, thrombophlebitis-3.8%, myalgia and ossalgia -15%, headache 3 Gd. prevented to continue Cap intake in 1 case(1.57%). No significant long-term toxicity was recorded. Conclusions: Cap has a satisfactory effect as well as controlled toxicity. The favorable long-term PFS and OS allow to use Cap in this heavily pretreated pts.

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Hyatt, N. C., M. C. Stennett, Ewan R. Maddrell und William Edward Lee. „Single Phase Ceramic Wasteforms for Plutonium Disposition“. Advances in Science and Technology 45 (Oktober 2006): 2004–11. http://dx.doi.org/10.4028/www.scientific.net/ast.45.2004.

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Four single phase ceramic formulations were investigated as potential wasteforms for plutonium disposition, using Ce as a Pu surrogate: pyrochlore, Gd2(Zr1-2xCexHfx)O7; zirconolite, (Ca1-x/2Gdx/2)(Zr1-5x/2CexHfxGdx/2)Ti2O7; britholite, (Ca2+xY8-2xCex)Si6O26; and kosnarite, Na(Zr2-xCex)P3O12. The single phase solid solution limits for each formulation were established and the processing parameters required to produce high quality ceramic specimens were optimised. This was achieved within the constraints of a generic processing route suitable for fabrication of Pu bearing samples. Whereas the pyrochlore, zirconolite and britholite formulations show considerable promise as single phase ceramic wasteforms, the kosnarite formulation was found to be unsuitable.

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Lin, Li, Feng Wang, Lin Yang, Li Jia Chen und Zheng Liu. „Solute Pre-Precipitation and Phase Transformation in a Mg-Zn-Gd Alloy“. Advanced Materials Research 152-153 (Oktober 2010): 864–67. http://dx.doi.org/10.4028/www.scientific.net/amr.152-153.864.

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A novel precipitation sequence, super-saturated-solution → stacking faults → Mg3Gd, i.e. S.S.S. → SF → β1, was established for a Mg-3Zn-2Gd (wt%) alloy. Solute pre-precipitation can occur during the solidification of as-cast alloy and subsequent solution-treatment, resulting in the formation of lamella structures with …ABCABC… stacking sequence. The lamella structure will transform to the Mg3Gd phase, even that Mg3Gd is not the most stable phase in this serial alloys.

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Leclercq, S., S. Matamoros, P. D. Cani, P. Stärkel, F. Bäckhed, V. Tremaroli, K. Windey, K. Verbeke, N. M. Delzenne und P. de Timary. „SY19-2GUT BACTERIAL DYSBIOSIS IS RELATED TO THE SEVERITY OF ALCOHOL-DEPENDENCE“. Alcohol and Alcoholism 50, suppl 1 (September 2015): i22.1—i22. http://dx.doi.org/10.1093/alcalc/agv076.79.

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Bolshchikov, F. A., Evgeny V. Zharikov, N. G. Zakharov, Denis A. Lis, P. A. Ryabochkina, Kirill A. Subbotin und Oleg L. Antipov. „Two-micron lasing in NaLa1/2Gd1/2(WO4)2crystalsdoped with Tm3+ions“. Quantum Electronics 40, Nr. 2 (28.02.2010): 101–2. http://dx.doi.org/10.1070/qe2010v040n02abeh014242.

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Zhong, Shiyu, Dingfei Zhang, Junyao Xu, Jie Zhou, Yang Zhao, Jingkai Feng, Yongqin Wang, Bin Jiang und Fusheng Pan. „Enhanced Degradability of Mg-2Gd Alloy by Alloying Cu“. Journal of The Electrochemical Society 168, Nr. 7 (01.07.2021): 071504. http://dx.doi.org/10.1149/1945-7111/ac0f5e.

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Tripathy, Diptimayee, Jyotshna Saikia, Amarjyoti Saikia und Arvind Pandey. „On the structure and ionic conductivity of Bi2V1-xTix/2Gdx/2O5.5-δ system“. Physica B: Condensed Matter 627 (Februar 2022): 413596. http://dx.doi.org/10.1016/j.physb.2021.413596.

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Дудникова, В. Б., und Е. В. Жариков. „Атомистическое моделирование натрий-гадолиниевого молибдата стехиометрического (Na-=SUB=-1/2-=/SUB=-Gd-=SUB=-1/2-=/SUB=-MoO-=SUB=-4-=/SUB=-) и катион-дефицитного (Na-=SUB=-2/7-=/SUB=-Gd-=SUB=-4/7-=/SUB=-MoO-=SUB=-4-=/SUB=-) составов“. Физика твердого тела 59, Nr. 5 (2017): 847. http://dx.doi.org/10.21883/ftt.2017.05.44370.359.

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Методом межатомных потенциалов проведено моделирование кристаллов натрий-гадолиниевых молибдатов как стехиометрического (Na1/2Gd1/2MoO4), так и катион-дефицитного (Na2/7Gd4/7MoO4) составов, в последнем из которых 1/7 соответствующих катионных позиций остается незанятой. Для катион-дефицитных кристаллов было рассмотрено два вида позиционного распределения катионов: статистическое распределение натрия, гадолиния и незанятых катионных позиций в структуре I41/a, а также частичное их упорядочение в рамках пространственной группы I4. В результате моделирования получены структурные характеристики натрий-гадолиниевых молибдатов, которые неплохо воспроизводят известные экспериментальные данные. Кроме того, предсказан ряд важных упругих и термодинамических свойств этих соединений. Сравниваются результаты, полученные в приближении частичной заселенности позиций и при конструировании сверхъячейки 7x2x2. Детально проанализирована локальная структура натрий-гадолиниевых молибдатов. Обсуждается вопрос влияния отклонения от стехиометрии и катионного упорядочения на свойства этих кристаллов. Работа выполнена при финансовой поддержке РФФИ, проект N 15-05-06742. DOI: 10.21883/FTT.2017.05.44370.359

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Fan, Jianyong, und Huilan Yang. „Construction and immune response of HSV–2gD–Hsp70 DNA vaccine“. Journal of Dermatological Science 57, Nr. 1 (Januar 2010): 64–66. http://dx.doi.org/10.1016/j.jdermsci.2009.10.012.

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Tang, Xiaoyan, Ye Xu, Wenpeng Ye, Yan Tang, Yunsheng Ma und Rongxin Yuan. „Mn(II)2Gd(III)3 Phosphonate as a Molecular Refrigerant“. Australian Journal of Chemistry 68, Nr. 12 (2015): 1926. http://dx.doi.org/10.1071/ch15520.

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3d-Gd phosphonate clusters are attractive for their potential applications as magnetic coolers. A new pentanuclear cluster [Mn(II)2Gd(III)3(OH)(dtbmfPO3)2(tBuCO2)8(HO2CtBu)(H2O)2]·HO2CtBu·CH3CN (1) (dtbmfPO3H2 = (2,7-di-tert-butyl-9-methyl-9H-fluoren-9-yl)phosphonic acid) has been synthesised and characterised. The cluster has a planar structure in which the trinuclear {MnGd2(OH)} and dinuclear {MnGdO2} units are joined together by two phosphonate groups. The magnetic studies reveal that 1 shows antiferromagnetic interactions and a large magnetocaloric effect (ΔS = 20.9 J kg–1 K–1 at ΔH = 7 T).

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Li, J. H., J. Barrirero, G. Sha, H. Aboulfadl, F. Mücklich und P. Schumacher. „Precipitation hardening of an Mg–5Zn–2Gd–0.4Zr (wt. %) alloy“. Acta Materialia 108 (April 2016): 207–18. http://dx.doi.org/10.1016/j.actamat.2016.01.053.

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García Blancas, Jesús, Omar Arturo Domínguez und Luis Enrique Ramos-Velasco. „Control Proporcional Multiresolución para un Robot de 2GDL a través de un Sistema BCI“. Pädi Boletín Científico de Ciencias Básicas e Ingenierías del ICBI 7, Especial (04.09.2019): 111–15. http://dx.doi.org/10.29057/icbi.v7iespecial.4395.

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Las complicaciones que presentan muchas personas con algún tipo de discapacidad motriz a la hora de hacer sus tareas cotidianas, ha despertado el interés de investigar los comandos cerebrales y entender las señales cerebrales generadas por una tarea definida, el objetivo es transformar estos comandos cerebrales en comandos de entrada a sistemas robóticos que ayuden a mejorar la calidad de vida de las personas de forma automática. Actualmente existe una gran cantidad de investigaciones que abordan el tema de los sistemas BCI, estos siguen presentando limitaciones a la hora de la implementación en tiempo real por la caracterización de las señales EEG y por el alto consumo computacional. El objetivo principal de este trabajo es mostrar la herramienta de multiresolución wavelet para el procesamiento de las señales cerebrales y, por otro lado, la implementación de un Control Multiresolución Proporcional que facilita cerrar el lazo del sistema BCI en tiempo real, y así mejorar los resultados actuales.

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Hernández García, Daniel Alberto, und Arturo Tena Colunga. „ESTUDIO PARAMÉTRICO DE MODELOS REPRESENTATIVOS DE ESTRUCTURAS PROPENSAS A DESARROLLAR PISOS SUAVES ANTE EXCITACIONES SÍSMICAS DE SUELO BLANDOS“. Revista de Ingeniería Sísmica, Nr. 95 (31.12.2016): 53–80. http://dx.doi.org/10.18867/ris.95.405.

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Se presenta un estudio paramétrico en modelos simplificados de dos grados de libertad (2gdl) que representan estructuras con disposición a desarrollar pisos suaves o débiles, donde se han variado las relaciones de rigideces y resistencia lateral entre ambos niveles de los modelos. Se condujeron análisis dinámicos no lineales paso a paso, utilizando 10 registros de aceleración sintéticos correspondientes a la zona III-a del lago de la ciudad de México y asociados al espectro de diseño del Apéndice A de las Normas Técnicas Complementarias para Diseño por Sismo del Reglamento para las Construcciones del Distrito Federal vigente. Con base en el estudio de los resultados obtenidos, en particular curvas de ductilidades y distorsiones máximas resultantes de estos análisis, se puede concluir que el mecanismo de piso suave o débil se previene o amplifica con una combinación adecuada de las propiedades mecánicas (rigidez y resistencia) de la estructura muy cercana a lo que actualmente proponen los reglamentos de diseño sísmico de México.

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Nie, Jing Jiang, Liang Meng, Xiu Rong Zhu, Yong Dong Xu, Yue Yi Wu, Rong Wang, Jun Wang, Hua Zhang, Min Chen und Li Jun Zhang. „Effect of Solution Treatment and Extrusion on the Microstructure and Mechanical Properties of a Mg-2Gd-Nd-0.4Zn-0.3Zr Alloy“. Advanced Materials Research 197-198 (Februar 2011): 1125–28. http://dx.doi.org/10.4028/www.scientific.net/amr.197-198.1125.

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The effect of the combined action of hot work and heat treatment on the microstructure and mechanical properties of a Mg-2Gd-Nd-0.4Zn-0.3Zr (wt. %) (E21) alloy was investigated. Results showed that the solution treatment time of the ingot played a great effect on the mechanical properties of the extruded alloy. With solution treating time of the ingot increasing, the tensile strength of the extruded alloy decreased gradually, but the elongation increased greatly. The best combination of strength and ductility was achieved for the extruded alloy after the ingot solution treated at 520°C for 3 h, extrusion at 400°C and aging at 200°C for 16 h, namely ultimate tensile strength = 331MPa and elongation = 7.1%.

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Aguirre Valverde, Jack Lut, Marco Antonio Becerra Pérez, Cristian Rafael Columna Zavaleta, Sthefanny Beatriz Reyna Rodríguez, Josmell Henry Alva Alcántara und Edgar André Manzano Ramos. „CONTROL ÓPTIMO LQR PARA ORIENTAR LA PLATAFORMA MÓVIL DE UN ROBOT PARALELO DE 2GDL EXPERIMENTAL“. Revista de Investigaciones 10, Nr. 4 (31.12.2021): 360–69. http://dx.doi.org/10.26788/riepg.v10i4.3500.

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El control de la orientación es una de las partes cruciales al momento de diseñar sistemas con una plataforma móvil, como en el caso de simuladores de vuelo o antenas de comunicación, ya que este control debe brindar precisión y estabilidad al sistema. El presente proyecto propone desarrollar el diseño de un sistema de control en base al regulador óptimo cuadrático lineal, con el objetivo de controlar la orientación de la plataforma móvil de un robot paralelo de 2 grados de libertad experimental. Nuestra metodología inicia con la construcción del robot paralelo, para luego poder obtener el modelo matemático que represente la dinámica del mismo, el cual nos permitirá realizar el control del sistema mediante el uso del regulador cuadrático lineal (LQR), con la finalidad de obtener respuestas rápidas y minimizar la aparición de sobre picos, obteniendo movimientos suaves; y, con ello, lograr la estabilidad completa del sistema. Este sistema de control propuesto se validará mediante datos de la orientación, obtenidos desde un sensor acelerómetro, con los cuales se verificará que el sistema mantenga una correcta orientación, evitando la generación de vibraciones en la plataforma móvil y haciendo una comparación con un controlador PID.

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Yang, Guang Yu, Jie Hua Li, Wan Qi Jie und Zhong Yu. „Study on Mechanical Properties and Microstructures of Mg-6Zn-2Gd-0.6Zr New Sand-Casting Magnesium Alloy“. Materials Science Forum 654-656 (Juni 2010): 651–54. http://dx.doi.org/10.4028/www.scientific.net/msf.654-656.651.

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A new composition sand-casting magnesium alloy, Mg-6Zn-2Gd-0.6Zr, was developed. It was found that the room temperature mechanical properties of the alloy were superior: b=270MPa, 0.2=175MPa, =8%. Meanwhile, the elevated-temperature strength and creep resistance were significantly improved, comparing with Mg-5Zn-0.6Zr (ZK51) commercial magnesium alloy. The as-cast microstructure of the alloy was mainly consisted of (Mg) matrix, (+Mg3Gd2Zn3+Mg3Gd) eutectic phase, which was distributed along the (Mg) grain boundary with coarse netted shape. After solid-solution treatment and subsequently aging treatment for the alloy, the secondary phases re-precipitated as fine discontinues semi-netted or short rod-like precipitations, also including some fine spherical precipitations in the  matrix, which were responsible for the properties improvement of the alloy.

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Zhao, Tianshuo, Yaobo Hu, Bing He, Chao Zhang, Tianxu Zheng und Fusheng Pan. „Effect of manganese on microstructure and properties of Mg-2Gd magnesium alloy“. Materials Science and Engineering: A 765 (September 2019): 138292. http://dx.doi.org/10.1016/j.msea.2019.138292.

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Zheng, Qiuxia, Zhanhui Wang, Zongbin Sun, Jiuba Wen, Tinghe Duan und Bingbing Zhang. „In vivo and in vitro performances of chitosan-coated Mg–Zn–Zr–Gd–Ca alloys as bone biodegradable materials in rat models“. Journal of Biomaterials Applications 36, Nr. 10 (11.03.2022): 1786–99. http://dx.doi.org/10.1177/08853282211052385.

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Mg alloys have attracted significant attention as promising biomedical materials, specifically as fixation materials for promoting fracture healing. However, their unsatisfactory corrosion resistances hinder further clinical applications and thus require attention. This study aims to determine the performance of novel chitosan-coated Mg–1Zn–0.3Zr–2Gd–1Ca alloy and its ability to promote the healing of osteoporotic fractures. Moreover, its corrosion resistance and biocompatibility were assessed. Performance degradations of the samples were measured via electrochemical tests, weight loss test and morphological analysis, and the uncoated and chitosan-coated fixations were compared based on their effects on biocompatibility via the cytotoxicity test, X-rays, and hematoxylin and eosin staining. The effect of bone growth and healing was investigated via immunohistochemical test. Results of the electrochemical tests indicated that compared with the bare body, chitosan-coated Mg–Zn–Ca–Zr–Gd alloys improved by one order of magnitude. Additionally, scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS), and weight loss test demonstrated that the corrosion resistance of the chitosan-coated Mg alloy is better than that of the uncoated alloy. In addition, cytotoxicity analysis indicated that the viability and morphology of the chitosan-coated alloy groups were superior to the uncoated groups in vitro. During in vivo analysis, chitosan-coated and uncoated Mg–1Zn–0.3Zr–2Gd–1Ca alloys were implanted into ovariectomized SD female rats with osteoporotic fractures for 1, 2, and 3 weeks. No displacement and shedding were observed through X-rays, and pathological analyses proved that the material was not harmful for liver and kidney tissues. Immunohistochemistry revealed that the chitosan-coated Mg–Zn–Ca–Zr–Gd alloy material contributed to the healing of osteoporotic fractures in the SD rat models. In conclusion, this study demonstrated the chitosan-coated Mg–Zn–Ca–Zr–Gd alloys have improved corrosion resistance and biocompatibility. Moreover, the alloy was found to accelerate the healing of osteoporotic fractures in SD rat models. Therefore, it has significant potential as a fixation material for osteoporotic fractures.

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Guo, Yong Chun, Jian Ping Li, Jin Shan Li, Zhong Yang und Ping Wang. „Phase Diagram of Mg-Zn-Gd System Alloy at Mg Rich Corner and its Application in the Development of Two New Alloys“. Materials Science Forum 765 (Juli 2013): 3–7. http://dx.doi.org/10.4028/www.scientific.net/msf.765.3.

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The Mg-rich corner of the equilibrium phase diagram of the Mg-Zn-Gd system has been calculated in detail using the phase diagram calculation software PANDAT and the thermodynamic database for Mg alloys. The calculated phase diagram includes the liquidus projection, isothermal sections and vertical sections. It is found that an increase of Zn content in the Mg-Gd alloy reduces the phase field of α-Mg + GdMg5. Based on the calculated phase diagrams, two alloys, Mg-5.5Zn-2Gd-0.5Zr and Mg-1.6Gd-5.5Zn-0.5Zr (wt.%), denoted as ZGK620 and ZGK616, were developed and their solidification and precipitation processes were analyzed in detail. The optimized thermal mechanical processing and heat-treatment processes were defined by referring to the calculated phase diagrams of the Mg-Zn-Gd system.

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Petrosyants, Svetlana P., Konstantin A. Babeshkin, Andrey B. Ilyukhin, Pavel S. Koroteev und Nikolay N. Efimov. „Something You Need Might Be under Your Feet: Molecular Magnetism of Heavy Kramers Lanthanide Hydrated Chlorides and Their Complexes with Polydentate Terpy Ligand“. Magnetochemistry 9, Nr. 1 (12.01.2023): 31. http://dx.doi.org/10.3390/magnetochemistry9010031.

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A study of the molecular magnetism of the hydrated salts [Ln(H2O)6Cl2]Cl (Ln = Gd (1Gd), Dy (1Dy), Er (1Er), Yb (1Yb)) and lanthanide chloride complexes with 2,2′;6′,2″-terpyridine (terpy) synthesized on their basis, [Ln(H2O)4(terpy)Cl]Cl2·3H2O (Ln = Gd (2Gd), Dy (2Dy), Er (2Er), and Yb (2Yb), was carried out. It was found that both the initial hydrated chlorides containing Dy, Er, Yb, and their derivatives with terpyridine exhibit the properties of single-molecule magnets. For the complexes with terpyridine, the values of the remagnetization barriers increase from Er to Dy, while for the aquachlorides, the corresponding values increase in the series Ueff (1Dy) < Ueff (1Er). It was found that magnetic relaxation in Yb complexes mostly proceeds according to the Raman mechanism.

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Liu, Ke, und Jian Meng. „Microstructures and mechanical properties of the extruded Mg-4Y-2Gd-xZn-0.4Zr alloys“. Journal of Alloys and Compounds 509, Nr. 7 (Februar 2011): 3299–305. http://dx.doi.org/10.1016/j.jallcom.2010.12.015.

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Niu, Hao-Yi, Fang-Fang Cao, Kun-Kun Deng, Kai-Bo Nie, Jin-Wen Kang und Hong-Wei Wang. „Microstructure and Corrosion Behavior of the As-Extruded Mg–4Zn–2Gd–0.5Ca Alloy“. Acta Metallurgica Sinica (English Letters) 33, Nr. 3 (19.12.2019): 362–74. http://dx.doi.org/10.1007/s40195-019-00984-2.

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Swami, Ashishkumar, Sangita Sharma und Liggy Andrews. „ASSESSMENT OF SOME NATURAL BIOACTIVE COMPOUNDS FOR INHIBITORY ACTIVITY AGAINST NOVEL COVID-19: A COMPUTATIONAL STUDY“. International Journal of Advanced Research 8, Nr. 9 (30.09.2020): 1201–21. http://dx.doi.org/10.21474/ijar01/11777.

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COVID-19 is a new coronavirus originated from Wuhan, China. In 2019. Twenty eight natural bioactive compounds (namely Amentoflavone, Apigenin, Bilobalide, Bilobetin, Catechin, Epigallocatechin, Fustin, Gallocatechin, Ginkgetin, Ginkgolide A, Ginkgolide B, Ginkgolide C, Glycitein, Isoginkgetin, Isorhamnetin, Kaempferol, Luteolin, Myricetin, Nobiletin, Procyanidin, Quercetin, Quercitrin, Rutin, Sciadopitysin, Tamarixetin, Ginkgolide J, Ginkgolide M, and Ginkgolide K) are selected for computational theoretical calculations of molecular docking with crestal structure of COVID-19 Main Protease 6LU7 and COVID-19 chymotrypsin-like protease Kinase- 2GTB. Lipinski\'s rule of five for drug likeness is applied to consider bioactive molecule as potential drug molecule. The interaction study is carried to assess to deactivate progression of COVID-19 using Auto Dock (4.2). Calculations are carried out on efficient shape-based search lemarckian genetic algorithm principle and a score base function. The binding energies are found between -5.59 to -1.75 in COVID-19 Main Protease 6LU7 and between -6.35 to -2.08 in chymotrypsin-like Protease 2GBT. Results from calculated data reveal that there is hydrogen bonding, electrostatic and vanderwaals are possible types of interactions. This data can help in identify best antiviral drug and consider some of the natural bioactive molecules as food supplements for development of inhibitor in the treatment of covid-19 stains.

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Moraes, Yuri José Oliveira, Antonio Almeida Silva, Marcelo Cavalcanti Rodrigues, Rômulo Pierre Dos Reis und Pedro Igor Moreira. „Análise dinâmica aplicada ao controle de vibrações em protótipo de edifício incorporando molas LMF superelásticas“. Revista Principia - Divulgação Científica e Tecnológica do IFPB 1, Nr. 45 (28.06.2019): 90. http://dx.doi.org/10.18265/1517-03062015v1n45p90-101.

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<p class="HOLOS-ResumoeAbstract"><span>O aumento da flexibilidade de estruturas civis em função de construções cada vez mais altas, esbeltas e com vãos maiores, resulta em uma vulnerabilidade do sistema à ação de cargas dinâmicas de causa humana ou natural. Essas estruturas, quando submetidas a essas forças, podem causar desconforto aos usuários e até seu colapso. Neste contexto, o controle destas vibrações faz-se necessário como forma de garantir ou evitar danos e falhas estruturais ao sistema. No presente trabalho estuda-se a aplicação de um sistema de controle passivo de vibrações através da incorporação de materiais inteligentes, como minimolas de uma Liga com Memória de Forma (LMF) em seu estado de superelasticidade. Numa primeira fase foram realizados estudos de modelagem analítica e numérica do sistema sem os elementos passivos e posteriormente testes dinâmicos experimentais para fins de validação do mecanismo de controle num pórtico de Dois Graus de Liberdade (2GDL), através da incorporação de fios de aço acoplados com as minimolas LMF, visando aumentar o amortecimento estrutural e reduzir a transmissibilidade de deslocamento do sistema. Nesse estudo foi concluído que a incorporação destes elementos pode apresentar resultados bastante satisfatórios para o controle de vibração em estruturas, quando esta é submetida à excitação dinâmica.</span></p>

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Hoseini-Athar, M. M., R. Mahmudi, R. Prasath Babu und P. Hedström. „Microstructure and superplasticity of Mg–2Gd–xZn alloys processed by equal channel angular pressing“. Materials Science and Engineering: A 808 (März 2021): 140921. http://dx.doi.org/10.1016/j.msea.2021.140921.

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Trivedi, Pramanshu, und Krishna C. Nune. „Bioactivity, cytocompatibility and effect of cells on degradation behavior of Mg–2Zn–2Gd alloy“. Nanomaterials and Energy 8, Nr. 2 (01.12.2019): 117–25. http://dx.doi.org/10.1680/jnaen.18.00019.

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Cao, Fang-fang, Kun-kun Deng, Kai-bo Nie, Jin-wen Kang und Hao-yi Niu. „Microstructure and corrosion properties of Mg-4Zn-2Gd-0.5Ca alloy influenced by multidirectional forging“. Journal of Alloys and Compounds 770 (Januar 2019): 1208–20. http://dx.doi.org/10.1016/j.jallcom.2018.08.191.

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Dudnikova, V. B., und E. V. Zharikov. „Atomistic simulation of sodium–gadolinium molybdate of stoichiometric (Na1/2Gd1/2MoO4) and cation-deficient (Na2/7Gd4/7MoO4) compositions“. Physics of the Solid State 59, Nr. 5 (Mai 2017): 866–77. http://dx.doi.org/10.1134/s1063783417050110.

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Šašek, Stanislav, Peter Minárik, Jitka Stráská, Klára Hosová, Jozef Veselý, Jiří Kubásek, Robert Král, Tomáš Krajňák und Dalibor Vojtěch. „Novel Ultrafine-Grain Mg-Gd/Nd-Y-Ca Alloys with an Increased Ignition Temperature“. Materials 16, Nr. 3 (03.02.2023): 1299. http://dx.doi.org/10.3390/ma16031299.

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Two novel ignition-resistant magnesium alloys, Mg-2Gd-2Y-1Ca and Mg-2Nd-1Y-1Ca, were prepared in the ultrafine-grain condition by equal channel angular pressing (ECAP). In addition, four commercial alloys—AZ31, AX41, AE42 and WE43—were prepared similarly as a reference. The microstructure, mechanical properties and ignition temperature were thoroughly investigated. Both novel alloys exhibited a mean grain size of ~1 µm and dense distribution of small secondary phase particles. The mechanical strength measured by the tensile deformation test showed that the novel alloys are much stronger (~290 MPa) than all commercial alloys except WE43. However, Ca segregation into the grain boundaries caused a significant decrease in ductility (<6%). The ignition temperature of the novel alloys (~950 °C) was considerably improved by the presence of Gd/Nd, Y and Ca. This study showed that both novel alloys exhibit high strength and high ignition temperature in the ultrafine-grain condition.

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Fujii, Shin, Takaaki Furubayashi und Toshihiko Nakata. „Design and Analysis of District Heating Systems Utilizing Excess Heat in Japan“. Energies 12, Nr. 7 (28.03.2019): 1202. http://dx.doi.org/10.3390/en12071202.

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District heating systems (DHSs) which utilize excess heat play an important role in energy infrastructure in many European countries. In contrast to Europe, the DHS is not common and excess heat is not reused effectively in Japan. Almost all the DHSs in Japan were designed as first-generation district heating (1GDH) systems or 2GDH systems. No 4GDH systems have been introduced in Japan. The present study designs a 4GDH system utilizing excess heat from a wide area of Northern Japan and evaluates its feasibility. First, available heat amounts from two excess heat resources were calculated: waste incineration plants and thermal power plants. Second, heat demand from both residential and commercial sectors was estimated using a 1 km mesh, and a heat load curve was created for each mesh based on load curve data. Third, the DHS was designed with excess heat plants as a supply-side heat resource, and spatial information of the demand side made use of the geographical information system (GIS). Further analysis was conducted on selected DHSs in three cities in order to evaluate those systems’ feasibility based on energy efficiency, CO2 emissions, and economic aspects. The result shows that 70.5 PJ of heat can be supplied by DHS in Northern Japan, replacing imported fossil fuels such as petroleum and LPG with regional excess heat. The designed DHS could supply heat with equivalent costs compared to European countries.

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Klyndyuk, A. I. „Structure and electrical conductivity of the ferrocuprate solid solutions Sm1/2Gd1/2BaCuFeO5.05, Gd1/2Yb1/2BaCuFeO5.02 and Ho1/3Yb2/3BaCuFeO5.05“. Russian Journal of Inorganic Chemistry 52, Nr. 3 (März 2007): 321–25. http://dx.doi.org/10.1134/s0036023607030047.

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Meng, Cheng, Wenqi Li, Chunrong Ren und Junchuan Zhao. „Structure and chemical durability studies of powellite ceramics Ca1−xLix/2Gdx/2MoO4 (0 ≤ x ≤ 1) for radioactive waste storage“. Journal of Materials Science 55, Nr. 7 (02.12.2019): 2741–49. http://dx.doi.org/10.1007/s10853-019-04223-y.

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Li, X., C. Liu und T. Al-Samman. „Microstructure and mechanical properties of Mg –2Gd –3Y –0.6Zr alloy upon conventional and hydrostatic extrusion“. Materials Letters 65, Nr. 11 (Juni 2011): 1726–29. http://dx.doi.org/10.1016/j.matlet.2011.02.073.

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Xiao, Lei, Guangyu Yang, Yang Liu, Shifeng Luo und Wanqi Jie. „Microstructure evolution, mechanical properties and diffusion behaviour of Mg-6Zn-2Gd-0.5Zr alloy during homogenization“. Journal of Materials Science & Technology 34, Nr. 12 (Dezember 2018): 2246–55. http://dx.doi.org/10.1016/j.jmst.2018.05.003.

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Zhang, Meng, Wei-Lin Deng, Xiao-Ning Yang, Yong-Kang Wang, Xiang-Yu Zhang, Rui-Qiang Hang, Kun-Kun Deng und Xiao-Bo Huang. „In vitro biodegradability of Mg–2Gd–xZn alloys with different Zn contents and solution treatments“. Rare Metals 38, Nr. 7 (07.03.2019): 620–28. http://dx.doi.org/10.1007/s12598-019-01220-7.

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Li, Lin, und Ping Shen. „Electrically driven wetting of high-entropy (Zr1/3Hf1/3Ce1/3)1-(Y1/2Gd1/2) O2-δ ceramics by molten Cu“. Scripta Materialia 233 (August 2023): 115518. http://dx.doi.org/10.1016/j.scriptamat.2023.115518.

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